NO862532D0 - PROCESS FOR THE PREPARATION OF NEW SOLID FORMS OF 2-ETHOXY-4- (N-1 (2-PIPERIDINO-PHENYL) -3-METHYL-1-BUTYL) -AMINOCARBONYLMETHYL) -BENZOIC ACID. - Google Patents

PROCESS FOR THE PREPARATION OF NEW SOLID FORMS OF 2-ETHOXY-4- (N-1 (2-PIPERIDINO-PHENYL) -3-METHYL-1-BUTYL) -AMINOCARBONYLMETHYL) -BENZOIC ACID.

Info

Publication number
NO862532D0
NO862532D0 NO862532A NO862532A NO862532D0 NO 862532 D0 NO862532 D0 NO 862532D0 NO 862532 A NO862532 A NO 862532A NO 862532 A NO862532 A NO 862532A NO 862532 D0 NO862532 D0 NO 862532D0
Authority
NO
Norway
Prior art keywords
aminocarbonylmethyl
piperidino
ethoxy
phenyl
butyl
Prior art date
Application number
NO862532A
Other languages
Norwegian (no)
Other versions
NO168302B (en
NO168302C (en
NO862532L (en
Inventor
Wolfgang Grell
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO862532D0 publication Critical patent/NO862532D0/en
Publication of NO862532L publication Critical patent/NO862532L/en
Publication of NO168302B publication Critical patent/NO168302B/en
Publication of NO168302C publication Critical patent/NO168302C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Glass Compositions (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Lubricants (AREA)

Abstract

1. Two new solid forms of 2-ethoxy-4-[N-(1-(2-piperidino- phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoic acid, the form designated (B) being characterised by the melting point of 140-142 degrees C and by the IR(KBr) spectrum according to Figure B' and the form designated (C) being characterised by a melting point of 75-85 degrees C and by the IR(KBr) spectrum according to Figure C'.
NO862532A 1983-12-30 1986-06-24 PROCEDURE FOR PREPARING CRYSTAL FORM (B) OF 2-ETHOXY-4- (N- (1- (2-PIPERIDINO-PHENYL) -3-METHYL-1-BUTYL) -AMINOCARBONYLMETHYL) -BENZOIC ACID NO168302C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833347565 DE3347565A1 (en) 1983-12-30 1983-12-30 NEW PHENYL ACETIC DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE19853522604 DE3522604A1 (en) 1983-12-30 1985-06-25 NEW SOLID FORMS OF 2- (GAMMA) THOXY-4- (N- (1- (2- (2-PIPERIDINO-PHENYL) -3-METHYL-1-BUTYL) -AMINOCARBONYLMETHYL) -BENZOESIC ACID, MEDICINAL PRODUCTS CONTAINING THESE FORMS

Publications (4)

Publication Number Publication Date
NO862532D0 true NO862532D0 (en) 1986-06-24
NO862532L NO862532L (en) 1986-12-29
NO168302B NO168302B (en) 1991-10-28
NO168302C NO168302C (en) 1992-02-05

Family

ID=37847099

Family Applications (3)

Application Number Title Priority Date Filing Date
NO845282A NO162819C (en) 1983-12-30 1984-12-28 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PHENYLEDIC ACETIC ACID DERIVATIVES.
NO862532A NO168302C (en) 1983-12-30 1986-06-24 PROCEDURE FOR PREPARING CRYSTAL FORM (B) OF 2-ETHOXY-4- (N- (1- (2-PIPERIDINO-PHENYL) -3-METHYL-1-BUTYL) -AMINOCARBONYLMETHYL) -BENZOIC ACID
NO1999016C NO1999016I1 (en) 1983-12-30 1999-07-20 Repaglinide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO845282A NO162819C (en) 1983-12-30 1984-12-28 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PHENYLEDIC ACETIC ACID DERIVATIVES.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO1999016C NO1999016I1 (en) 1983-12-30 1999-07-20 Repaglinide

Country Status (26)

Country Link
EP (2) EP0147850B1 (en)
JP (2) JPH0623200B2 (en)
KR (1) KR900005320B1 (en)
AT (1) ATE44027T1 (en)
AU (2) AU577815B2 (en)
BG (1) BG61519B2 (en)
CA (2) CA1225398A (en)
CS (1) CS409791A3 (en)
DD (1) DD231348A5 (en)
DE (4) DE3347565A1 (en)
DK (2) DK167439B1 (en)
ES (7) ES8605500A1 (en)
FI (2) FI80447C (en)
GR (2) GR82614B (en)
HK (1) HK87492A (en)
HU (1) HU194548B (en)
IE (1) IE57700B1 (en)
IL (2) IL73963A (en)
LU (1) LU90301I2 (en)
MX (1) MX9202772A (en)
NL (1) NL980034I1 (en)
NO (3) NO162819C (en)
NZ (2) NZ210657A (en)
PT (2) PT79772B (en)
SG (1) SG55492G (en)
ZA (2) ZA8410103B (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3347565A1 (en) * 1983-12-30 1985-07-11 Thomae Gmbh Dr K NEW PHENYL ACETIC DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE3523466A1 (en) * 1985-07-01 1987-01-08 Thomae Gmbh Dr K NEW PHENYL ACETIC DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
AU660930B2 (en) * 1991-06-21 1995-07-13 Novo Nordisk A/S (S)(+)-2-ethoxy-4-(N-(1-(2-piperidinophenyl)-3-methyl-1- butyl)aminocarbonylmethyl)benzoic acid
ES2136600T3 (en) * 1991-06-21 1999-12-01 Boehringer Ingelheim Pharma USE OF ACID (S) (+) - 2-ETOXI-4- (N- (1- (2-PIPERIDINO-FENIL) -3-METHYL-1-BUTYL) AMINO CARBONYL METHYL) -BENZOIC FOR THE PREPARATION OF A LONG ANTIDIABETIC DURATION.
FR2763590B1 (en) * 1997-05-22 2000-03-24 Synthelabo ACID DERIVATIVES [[[(ARYLMETHYL) AMINO] CARBONYL] ALKYL] - AROMATICS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
PT1248604E (en) 2000-01-21 2007-01-31 Novartis Ag Combinations comprising dipeptidylpeptidase-iv inhibitors and antidiabetic agents
AU2003260078A1 (en) * 2002-08-23 2004-03-11 Dr. Reddy's Laboratories Limited Crystalline and amorphous forms of (s) -repaglinide and the processes for preparation thereof
WO2004101540A2 (en) * 2003-05-14 2004-11-25 Cilag Ag Method for the production of phenylacetic acid derivatives
WO2004103983A1 (en) * 2003-05-26 2004-12-02 Biocon Limited Process for the preparation of s(+)-2-ethoxy-4-[n-{1-(2-piperidinophelyl)-3-methyl-1- butyl} aminocarbonylmethyl]benzoic acid derivatives
CA2526506A1 (en) * 2003-06-09 2004-12-16 Boehringer Ingelheim International Gmbh Inhibitors of papilloma virus
FR2875805B1 (en) * 2004-09-27 2006-12-29 Genfit S A SUBSTITUTED N- (BENZYL) PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION AND USES
CN1305863C (en) * 2004-12-27 2007-03-21 浙江大学 Method for synthesizing (S)-isopropyl-(2-piperidine) phenyl-methylhistamine
GT200600381A (en) 2005-08-25 2007-03-28 ORGANIC COMPOUNDS
ES2445180T5 (en) 2005-09-14 2022-02-01 Takeda Pharmaceuticals Co Administration of dipeptidyl peptidase inhibitors
EP2177221A1 (en) 2008-10-20 2010-04-21 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of substantially optically pure Repaglinide and precursors thereof
MA33358B1 (en) 2009-05-15 2012-06-01 Novartis Ag Arylperidine as aldosterone synthase inhibitors
AU2010247391A1 (en) 2009-05-15 2011-12-01 Novartis Ag Benzoxazolone derivatives as aldosterone synthase inhibitors
SG176010A1 (en) 2009-05-28 2011-12-29 Novartis Ag Substituted aminobutyric derivatives as neprilysin inhibitors
ME01923B (en) 2009-05-28 2015-05-20 Novartis Ag Substituted aminopropionic derivatives as neprilysin inhibitors
WO2011041293A1 (en) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
CN102712589B (en) 2009-11-17 2015-05-13 诺华股份有限公司 Aryl-pyridine derivatives as aldosterone synthase inhibitors
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors
JP5575913B2 (en) 2009-11-30 2014-08-20 ノバルティス アーゲー Imidazole derivatives as aldosterone synthase inhibitors
ES2445917T3 (en) 2010-02-03 2014-03-06 Takeda Pharmaceutical Company Limited Inhibitors of apoptosis signal regulatory kinase 1
US8877815B2 (en) 2010-11-16 2014-11-04 Novartis Ag Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
US8673974B2 (en) 2010-11-16 2014-03-18 Novartis Ag Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
WO2012095548A2 (en) 2011-01-13 2012-07-19 Centro De Investigación Biomédica En Red De Enfermedades Neurodegenerativas (Ciberned) Compounds for treating neurodegenerative disorders
UY35144A (en) 2012-11-20 2014-06-30 Novartis Ag APELINE SYNTHETIC LINEAR MIMETICS FOR THE CARDIAC INSUFFICIENCY TREATMENT
MA38330B1 (en) 2013-02-14 2016-09-30 Novartis Ag Butanoic phosphonic acid derivatives of bisphenol substituted as nep inhibitors (neutral endopeptidase)
EP3024845A1 (en) 2013-07-25 2016-06-01 Novartis AG Cyclic polypeptides for the treatment of heart failure
CN105705167A (en) 2013-07-25 2016-06-22 诺华股份有限公司 Bioconjugates of synthetic APELIN polypeptides
JP2018507187A (en) 2015-01-23 2018-03-15 ノバルティス アーゲー Synthetic apelin fatty acid conjugates with improved half-life
UY38072A (en) 2018-02-07 2019-10-01 Novartis Ag COMPOSITIONS DERIVED FROM BUTANOIC ESTER SUBSTITUTED WITH BISPHENYL AS INHIBITORS OF NEP, COMPOSITIONS AND COMBINATIONS OF THE SAME

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3100575A1 (en) * 1981-01-10 1982-09-02 Dr. Karl Thomae Gmbh, 7950 Biberach "NEW BENZOESAEURS, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS"
DE3100535A1 (en) * 1981-01-10 1982-08-12 Dr. Karl Thomae Gmbh, 7950 Biberach "NEW CARBONIC ACID DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS"
DE3375783D1 (en) * 1982-07-06 1988-04-07 Thomae Gmbh Dr K Phenyl-acetic-acid derivatives, their preparation and pharmaceutical compostions containing them
FR2554875B1 (en) * 1983-11-10 1986-02-28 Dba HYDRAULIC BRAKE AMPLIFIER
DE3347565A1 (en) * 1983-12-30 1985-07-11 Thomae Gmbh Dr K NEW PHENYL ACETIC DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE3523466A1 (en) * 1985-07-01 1987-01-08 Thomae Gmbh Dr K NEW PHENYL ACETIC DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
IL73963A (en) 1989-01-31
EP0147850A3 (en) 1985-08-07
NZ210657A (en) 1988-10-28
NO168302B (en) 1991-10-28
IL79217A0 (en) 1986-09-30
AU583631B2 (en) 1989-05-04
JPH0623200B2 (en) 1994-03-30
PT82832B (en) 1988-12-15
DE3347565A1 (en) 1985-07-11
DE3522604A1 (en) 1987-01-08
EP0207331B1 (en) 1990-05-23
JPH0739405B2 (en) 1995-05-01
DK296686A (en) 1986-12-26
HUT37773A (en) 1986-02-28
ES545881A0 (en) 1986-02-01
NO168302C (en) 1992-02-05
CA1292000C (en) 1991-11-12
JPS60158171A (en) 1985-08-19
DE3478682D1 (en) 1989-07-20
DK167573B1 (en) 1993-11-22
ES545882A0 (en) 1986-02-01
NO1999016I1 (en) 1999-07-20
FI845145A0 (en) 1984-12-28
ATE44027T1 (en) 1989-06-15
ES8604545A1 (en) 1986-02-01
AU5913986A (en) 1987-01-08
DD231348A5 (en) 1985-12-24
EP0147850A2 (en) 1985-07-10
ZA8410103B (en) 1986-09-24
IE57700B1 (en) 1993-03-10
ZA864695B (en) 1988-02-24
DK296686D0 (en) 1986-06-24
ES8604544A1 (en) 1986-02-01
KR850004590A (en) 1985-07-25
HU194548B (en) 1988-02-29
DK613184A (en) 1985-07-01
ES8604547A1 (en) 1986-02-01
BG61519B2 (en) 1997-10-31
AU577815B2 (en) 1988-10-06
NO845282L (en) 1985-07-01
DK613184D0 (en) 1984-12-20
MX9202772A (en) 1992-06-30
HK87492A (en) 1992-11-13
PT79772B (en) 1987-01-05
CS409791A3 (en) 1992-07-15
FI82689B (en) 1990-12-31
ES8604546A1 (en) 1986-02-01
NL980034I1 (en) 1999-02-01
NZ216640A (en) 1989-02-24
IL73963A0 (en) 1985-03-31
GR861558B (en) 1986-10-17
EP0207331A1 (en) 1987-01-07
ES539078A0 (en) 1986-03-16
IL79217A (en) 1991-01-31
ES545880A0 (en) 1986-02-01
FI82689C (en) 1991-04-10
ES8802145A1 (en) 1988-04-01
ES545883A0 (en) 1986-02-01
PT79772A (en) 1985-01-01
ES545879A0 (en) 1986-02-01
EP0147850B1 (en) 1989-06-14
GR82614B (en) 1985-05-02
NO862532L (en) 1986-12-29
ES8604548A1 (en) 1986-02-01
DE19875044I2 (en) 2002-07-18
ES8605500A1 (en) 1986-03-16
ES556495A0 (en) 1988-04-01
FI862650A (en) 1986-12-26
PT82832A (en) 1986-07-01
DK167439B1 (en) 1993-11-01
FI845145L (en) 1985-07-01
AU3721084A (en) 1985-08-01
JPS62474A (en) 1987-01-06
NO162819B (en) 1989-11-13
CA1225398A (en) 1987-08-11
KR900005320B1 (en) 1990-07-27
FI80447C (en) 1990-06-11
FI80447B (en) 1990-02-28
NO162819C (en) 1990-02-21
IE843349L (en) 1985-06-30
FI862650A0 (en) 1986-06-23
SG55492G (en) 1992-10-02
LU90301I2 (en) 1998-12-21

Similar Documents

Publication Publication Date Title
NO862532D0 (en) PROCESS FOR THE PREPARATION OF NEW SOLID FORMS OF 2-ETHOXY-4- (N-1 (2-PIPERIDINO-PHENYL) -3-METHYL-1-BUTYL) -AMINOCARBONYLMETHYL) -BENZOIC ACID.

Legal Events

Date Code Title Description
MK1K Patent expired