NO840131L - Fremgangsmaate ved fremstilling av nye bicyklo (4.2.0)1,3,5-oktarienderivater - Google Patents

Fremgangsmaate ved fremstilling av nye bicyklo (4.2.0)1,3,5-oktarienderivater

Info

Publication number
NO840131L
NO840131L NO840131A NO840131A NO840131L NO 840131 L NO840131 L NO 840131L NO 840131 A NO840131 A NO 840131A NO 840131 A NO840131 A NO 840131A NO 840131 L NO840131 L NO 840131L
Authority
NO
Norway
Prior art keywords
octarian
derivatives
procedure
preparation
carbon atoms
Prior art date
Application number
NO840131A
Other languages
English (en)
Other versions
NO159379B (no
NO159379C (no
Inventor
Charles Malen
Jean-Louis Peglion
Michel Laubie
Jean-Claude Poignant
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of NO840131L publication Critical patent/NO840131L/no
Publication of NO159379B publication Critical patent/NO159379B/no
Publication of NO159379C publication Critical patent/NO159379C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
  • Fats And Perfumes (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Nye bicyklo[4.2.0]1,3,5-oktatrienforbindelser med den generelle formel:I. hvori. og Rhver betyr et hydrogenatom, et halogenatom,. en alkyl- eller alkoksygruppe, en sulfonamidrest som kan være substituert med en alkylrest med fra 1 til 4 kar-bonatomer, eller de betyr tilsammen en metylen-dioksy-rest, n betyr et heltall lik 0 eller 1,. i racemisk form eller i form av optiske isomerer,. og deres addisjonssalter med farmasøytisk fordrage-lige syrer.Fremstilling av forbindelsene er beskrevet. De er anven-delige i behandling spesielt av hypertensjon, depresjon, astma, diabetes.
NO840131A 1983-01-14 1984-01-13 Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye bicyklo (4.2.0)1,3,5-oktatrienderivater. NO159379C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8300502A FR2539415B1 (fr) 1983-01-14 1983-01-14 Derives de la d-2 imidazoline, leur preparation et leur application en therapeutique

Publications (3)

Publication Number Publication Date
NO840131L true NO840131L (no) 1984-07-16
NO159379B NO159379B (no) 1988-09-12
NO159379C NO159379C (no) 1988-12-21

Family

ID=9284924

Family Applications (1)

Application Number Title Priority Date Filing Date
NO840131A NO159379C (no) 1983-01-14 1984-01-13 Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye bicyklo (4.2.0)1,3,5-oktatrienderivater.

Country Status (17)

Country Link
US (1) US4567181A (no)
EP (1) EP0119107B1 (no)
JP (1) JPS59139361A (no)
AT (1) ATE22557T1 (no)
AU (1) AU562182B2 (no)
CA (1) CA1212111A (no)
DE (1) DE3460834D1 (no)
DK (1) DK12584A (no)
ES (1) ES8503681A1 (no)
FR (1) FR2539415B1 (no)
GR (1) GR79170B (no)
IL (1) IL70684A (no)
NO (1) NO159379C (no)
NZ (1) NZ206833A (no)
OA (1) OA07633A (no)
PT (1) PT77961B (no)
ZA (1) ZA84261B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166937B1 (en) * 1984-06-06 1991-08-28 Abbott Laboratories Adrenergic compounds
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
US4923444A (en) * 1988-12-19 1990-05-08 Ivac Corporation Negative pressure measurement system
CA1321751C (en) * 1989-02-21 1993-08-31 Eugene C. Crichlow Mechanism mediating ruminal stasis in ruminal lactic acidosis
JP3761960B2 (ja) * 1996-03-19 2006-03-29 仁美 鈴木 ガス中の二酸化炭素の除去方法
FR2935381B1 (fr) * 2008-08-29 2010-12-17 Servier Lab Nouveau procede de resolution des enantiomerees du (3,4-dimethoxy-bicyclo°4.2.0!octa-1,3,5-trien-7-yl)nitrile et application a la synthese de l'ivabradine
KR101986859B1 (ko) * 2011-07-04 2019-06-07 캠브리지 디스플레이 테크놀로지 리미티드 중합체, 단량체 및 중합체의 형성 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE551610A (no) * 1955-10-13 1900-01-01
US3287469A (en) * 1963-09-27 1966-11-22 Du Pont Naphthyl-and indanylimidazolines
US3927023A (en) * 1974-05-24 1975-12-16 Warner Lambert Co Imidazolyl benzofurans
US4226876A (en) * 1976-12-20 1980-10-07 Burroughs Wellcome Co. Arthropodicidal imidazoline derivatives
DE2933962A1 (de) * 1979-08-22 1981-03-26 Hoechst Ag, 65929 Frankfurt Verfahren zur herstellung von 4,5-dichlor-imidazolen.
NZ201219A (en) * 1981-07-28 1984-10-19 Reckitt & Colmann Prod Ltd Dihydrobenzofuranyl-2-imidazolines and pharmaceutical compositions

Also Published As

Publication number Publication date
PT77961A (fr) 1984-02-01
NO159379B (no) 1988-09-12
PT77961B (fr) 1986-06-18
IL70684A0 (en) 1984-04-30
JPS632957B2 (no) 1988-01-21
NZ206833A (en) 1987-02-20
FR2539415B1 (fr) 1985-09-13
ZA84261B (en) 1984-08-29
OA07633A (fr) 1985-05-23
DE3460834D1 (en) 1986-11-06
DK12584A (da) 1984-07-15
EP0119107A1 (fr) 1984-09-19
JPS59139361A (ja) 1984-08-10
FR2539415A1 (fr) 1984-07-20
ES528877A0 (es) 1985-03-01
ES8503681A1 (es) 1985-03-01
ATE22557T1 (de) 1986-10-15
NO159379C (no) 1988-12-21
CA1212111A (fr) 1986-09-30
DK12584D0 (da) 1984-01-12
AU562182B2 (en) 1987-06-04
GR79170B (no) 1984-10-02
AU2327784A (en) 1984-07-19
IL70684A (en) 1987-07-31
EP0119107B1 (fr) 1986-10-01
US4567181A (en) 1986-01-28

Similar Documents

Publication Publication Date Title
LU91587I2 (fr) Agomélatine et ses dérivés pharmaceutiquement acceptables (VALDOXAN)
NO162518C (no) Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive 8-klor-1,5-benzothiazepinderivater.
ES510649A0 (es) "procedimiento para la preparacion de 9-(2-(3-indolil)-etil)-1-oxa-4,9-diazaspiro (5.5) undecan-3-onas".
ES526318A0 (es) Procedimiento para la obtencion de derivados de 1-hidroxietil-triazolilo sustituidos
IT1171880B (it) Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica e procedimento per la loro produzione
DK160505C (da) Analogifremgangsmaade til fremstilling af 6alfa-methylprednisolonderivater
ES2037098T3 (es) Procedimiento de preparacion de derivados de la decahidroquinoleina.
SE8403801D0 (sv) Nya bensotiazepiner med kardiovaskuler anvendbarhet, forfarande for framstellning derav och farmaceutiska kompositioner som innehaller dem
NO840131L (no) Fremgangsmaate ved fremstilling av nye bicyklo (4.2.0)1,3,5-oktarienderivater
SE8102220L (sv) Anvendning av substituerade derivat av 4-fenyl-4-oxo-2-butensyra sasom lekemedel
NO832333L (no) Analogifremgangsmaate ved fremstilling av terapeutisk virksomme polyolefiniske alfa-alkyl-carboxylsyrer
SE7709158L (sv) Nya substituerade 2-fenylaminoimidazolin-(2)-er, syraadditionssalter derav, lekemedel som innehaller dessa och forfarande for framstellning derav
SE8005686L (sv) Nya halogenvinkamonderivat jemte sett for deras framstellning
SE8803765L (sv) Nya isopolypeptider samt foerfarande foer framstaellning av desamma
SE8005687L (sv) Nya 10-halogen-e-homoeburnaner jemte sett for deras framstellning
FI861934A (fi) Nya isoxazolderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska preparat.
ES519530A0 (es) Procedimiento para la preparacion de tienobenzodiazepinonas sustituidas.
IT1191109B (it) Derivati di acidi aminopiridincarbossilici,loro metodo di sintesi e composizioni farmaceutiche che li contengono
IT1204494B (it) Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci
ES536139A0 (es) Procedimiento para la preparacion de quinolinonas-4
SE7901707L (sv) 2-betoxibensamider
AT383599B (de) Verfahren zur herstellung von neuen racemischen und optisch aktiven e-homo-eburnan-derivaten sowievon saeureadditions-salzen derselben
ES501744A0 (es) Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminas
FI875626A0 (fi) Foerfarande foer framstaellning av dibenzo/be/ixepinaettiksyraderivat.