NO822902L - Beta-laktamer. - Google Patents
Beta-laktamer.Info
- Publication number
- NO822902L NO822902L NO822902A NO822902A NO822902L NO 822902 L NO822902 L NO 822902L NO 822902 A NO822902 A NO 822902A NO 822902 A NO822902 A NO 822902A NO 822902 L NO822902 L NO 822902L
- Authority
- NO
- Norway
- Prior art keywords
- manufacture
- lactams
- beta
- readily cleavable
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/14—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH552481 | 1981-08-27 | ||
| CH392582 | 1982-06-25 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO822902L true NO822902L (no) | 1983-02-28 |
| NO159931B NO159931B (no) | 1988-11-14 |
| NO159931C NO159931C (no) | 1989-02-22 |
Family
ID=25694185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO822902A NO159931C (no) | 1981-08-27 | 1982-08-26 | Optisk enhetlige beta-laktamer, samt en fremgangsmaate for fremstilling av disse. |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US4576751A (no) |
| EP (2) | EP0073061B1 (no) |
| KR (1) | KR880000432B1 (no) |
| AT (2) | ATE30017T1 (no) |
| AU (2) | AU555097B2 (no) |
| CA (1) | CA1262128A (no) |
| DE (2) | DE3275543D1 (no) |
| DK (1) | DK168433B1 (no) |
| ES (1) | ES8401935A1 (no) |
| HU (1) | HU190697B (no) |
| IE (1) | IE53791B1 (no) |
| IL (1) | IL66619A0 (no) |
| NO (1) | NO159931C (no) |
| NZ (1) | NZ201660A (no) |
| PH (1) | PH21581A (no) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4782147A (en) * | 1980-12-05 | 1988-11-01 | Takeda Chemical Industries, Ltd. | 1-sulfo-2-oxoazetidine derivatives and their production |
| US4572801A (en) * | 1981-04-30 | 1986-02-25 | Takeda Chemical Industries, Ltd. | 4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production |
| AU564150B2 (en) * | 1982-04-30 | 1987-08-06 | Takeda Chemical Industries Ltd. | 1-sulfo-2-azetidinone derivatives |
| EP0096296B1 (de) * | 1982-06-03 | 1987-07-29 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | 1-Sulfo-2-oxoazetidinderivate |
| CA1204746A (en) * | 1982-08-19 | 1986-05-20 | Hoffmann-La Roche Limited | .beta. LACTAMS |
| US4663469A (en) * | 1982-12-09 | 1987-05-05 | Hoffman-La Roche Inc. | 4-hydroxy-l-threoninamides |
| US4502994A (en) * | 1982-12-09 | 1985-03-05 | Hoffmann-La Roche Inc. | Enantiomeric synthesis of 3-amino-4-carbamoyloxymethyl-2-azetidonone-1-sulfate |
| CA1251454A (en) * | 1983-01-20 | 1989-03-21 | Gerard Schmid | PROCESS FOR THE MANUFACTURE OF .beta.-LACTAMES |
| DK36784A (da) * | 1983-02-25 | 1984-08-26 | Hoffmann La Roche | Fremgangsmaade til fremstilling af chirale aldehyder |
| US4501697A (en) * | 1983-06-17 | 1985-02-26 | E. R. Squibb & Sons, Inc. | 4-[[(Amidomethyl)oxy]methyl]-2-oxo-1-azetidinesulfonic acid salts |
| DK411384A (da) * | 1983-10-03 | 1985-04-04 | Hoffmann La Roche | Fremgangsmaade til fremstilling af azetidinonderivater |
| EP0146735A1 (de) * | 1983-11-23 | 1985-07-03 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Optisch einheitliche beta-Lactame |
| JPS60139667A (ja) * | 1983-12-27 | 1985-07-24 | Takeda Chem Ind Ltd | アゼチジノンの製造法 |
| GB8717446D0 (en) * | 1987-07-23 | 1987-08-26 | Merck Sharp & Dohme | Chemical compounds |
| US4937331A (en) * | 1988-03-25 | 1990-06-26 | President And Fellows Of Harvard College | Chiral azetidinone epoxides |
| PL2197881T3 (pl) * | 2007-09-17 | 2013-09-30 | Basilea Pharmaceutica Ag | Sposób wytwarzania związków pośrednich dla mostkowanych monobaktamów |
| UY34585A (es) | 2012-01-24 | 2013-09-02 | Aicuris Gmbh & Co Kg | Compuestos b-lactámicos sustituidos con amidina, su preparación y uso |
| CN103044416A (zh) * | 2012-12-17 | 2013-04-17 | 浙江华方药业有限责任公司 | 一种卡芦莫南钠的合成方法 |
| AU2015236369B2 (en) | 2014-03-24 | 2017-02-16 | Novartis Ag | Monobactam organic compounds for the treatment of bacterial infections |
| AU2016327264B2 (en) | 2015-09-23 | 2019-06-27 | Novartis Ag | Salts and solid forms of monobactam antibiotic |
| US11414411B2 (en) | 2017-08-02 | 2022-08-16 | Novartis Ag | Chemical process for manufacturing monobactam antibiotic and intermediates thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK194776A (da) * | 1975-05-05 | 1976-11-06 | Smithkline Corp | Antibakterielle midler og mellemprodukter dertil |
| GB1570278A (en) * | 1975-10-06 | 1980-06-25 | Fujisawa Pharmaceutical Co | O-substituted-2-azetidinone derivatives and the preparation thereof |
| JPS609514B2 (ja) * | 1976-08-05 | 1985-03-11 | 塩野義製薬株式会社 | ７−アミノ−３′−ノルセファロスポラン酸類 |
| US4202978A (en) * | 1978-02-08 | 1980-05-13 | Hoffmann-La Roche Inc. | (S)-1-[2-(4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines |
| US4473502A (en) * | 1981-04-08 | 1984-09-25 | Merck & Co., Inc. | Synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid |
-
1982
- 1982-07-29 CA CA000408343A patent/CA1262128A/en not_active Expired
- 1982-08-11 US US06/407,027 patent/US4576751A/en not_active Expired - Fee Related
- 1982-08-19 DK DK373082A patent/DK168433B1/da not_active IP Right Cessation
- 1982-08-20 NZ NZ201660A patent/NZ201660A/en unknown
- 1982-08-23 AU AU87523/82A patent/AU555097B2/en not_active Ceased
- 1982-08-23 IL IL66619A patent/IL66619A0/xx not_active IP Right Cessation
- 1982-08-24 HU HU822715A patent/HU190697B/hu not_active IP Right Cessation
- 1982-08-25 AT AT84115022T patent/ATE30017T1/de not_active IP Right Cessation
- 1982-08-25 EP EP82107790A patent/EP0073061B1/de not_active Expired
- 1982-08-25 AT AT82107790T patent/ATE25676T1/de active
- 1982-08-25 EP EP84115022A patent/EP0156976B1/de not_active Expired
- 1982-08-25 DE DE8282107790T patent/DE3275543D1/de not_active Expired
- 1982-08-25 DE DE8484115022T patent/DE3277410D1/de not_active Expired
- 1982-08-26 PH PH27783A patent/PH21581A/en unknown
- 1982-08-26 ES ES515255A patent/ES8401935A1/es not_active Expired
- 1982-08-26 NO NO822902A patent/NO159931C/no unknown
- 1982-08-26 IE IE2067/82A patent/IE53791B1/en not_active IP Right Cessation
- 1982-08-27 KR KR8203877A patent/KR880000432B1/ko active
-
1985
- 1985-08-26 US US06/769,536 patent/US4617150A/en not_active Expired - Fee Related
- 1985-08-26 US US06/769,634 patent/US4699986A/en not_active Expired - Lifetime
-
1986
- 1986-03-12 AU AU54671/86A patent/AU576951B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0073061B1 (de) | 1987-03-04 |
| ES515255A0 (es) | 1984-01-16 |
| NO159931C (no) | 1989-02-22 |
| ATE30017T1 (de) | 1987-10-15 |
| IE822067L (en) | 1983-02-27 |
| KR880000432B1 (ko) | 1988-03-24 |
| EP0073061A3 (en) | 1983-06-15 |
| CA1262128A (en) | 1989-10-03 |
| US4576751A (en) | 1986-03-18 |
| EP0156976A2 (de) | 1985-10-09 |
| DK168433B1 (da) | 1994-03-28 |
| PH21581A (en) | 1987-12-11 |
| US4699986A (en) | 1987-10-13 |
| DK373082A (da) | 1983-02-28 |
| EP0156976B1 (de) | 1987-09-30 |
| IL66619A0 (en) | 1982-12-31 |
| ES8401935A1 (es) | 1984-01-16 |
| AU8752382A (en) | 1983-03-03 |
| NZ201660A (en) | 1986-01-24 |
| IE53791B1 (en) | 1989-02-15 |
| DE3275543D1 (en) | 1987-04-09 |
| EP0073061A2 (de) | 1983-03-02 |
| DE3277410D1 (en) | 1987-11-05 |
| AU555097B2 (en) | 1986-09-11 |
| HU190697B (en) | 1986-10-28 |
| AU5467186A (en) | 1986-07-31 |
| NO159931B (no) | 1988-11-14 |
| US4617150A (en) | 1986-10-14 |
| ATE25676T1 (de) | 1987-03-15 |
| EP0156976A3 (en) | 1986-06-04 |
| AU576951B2 (en) | 1988-09-08 |
| KR840001135A (ko) | 1984-03-28 |
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