NO801014L - PROCEDURE FOR THE PREPARATION OF NEW PIPERIDE INGREDIENTS - Google Patents

PROCEDURE FOR THE PREPARATION OF NEW PIPERIDE INGREDIENTS

Info

Publication number
NO801014L
NO801014L NO801014A NO801014A NO801014L NO 801014 L NO801014 L NO 801014L NO 801014 A NO801014 A NO 801014A NO 801014 A NO801014 A NO 801014A NO 801014 L NO801014 L NO 801014L
Authority
NO
Norway
Prior art keywords
procedure
preparation
new
piperide
ingredients
Prior art date
Application number
NO801014A
Other languages
Norwegian (no)
Other versions
NO154521C (en
NO154521B (en
Inventor
Albert A Carr
Joseph E Dolfini
George J Wright
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21845568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO801014(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of NO801014L publication Critical patent/NO801014L/en
Publication of NO154521B publication Critical patent/NO154521B/en
Publication of NO154521C publication Critical patent/NO154521C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO801014A 1979-04-10 1980-04-09 ANALOGY PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE PIPERIDE INGREDIENTS. NO154521C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/028,813 US4254129A (en) 1979-04-10 1979-04-10 Piperidine derivatives

Publications (3)

Publication Number Publication Date
NO801014L true NO801014L (en) 1980-10-13
NO154521B NO154521B (en) 1986-06-30
NO154521C NO154521C (en) 1986-10-08

Family

ID=21845568

Family Applications (2)

Application Number Title Priority Date Filing Date
NO801014A NO154521C (en) 1979-04-10 1980-04-09 ANALOGY PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE PIPERIDE INGREDIENTS.
NO1998017C NO1998017I1 (en) 1979-04-10 1998-05-29 Fexofenadine

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO1998017C NO1998017I1 (en) 1979-04-10 1998-05-29 Fexofenadine

Country Status (19)

Country Link
US (1) US4254129A (en)
JP (1) JPS55141469A (en)
AT (1) AT376208B (en)
AU (1) AU531146B2 (en)
BE (1) BE882703A (en)
CA (1) CA1123438A (en)
CH (1) CH643245A5 (en)
DE (1) DE3007498A1 (en)
DK (1) DK153709C (en)
ES (1) ES8103735A1 (en)
FR (1) FR2453854A1 (en)
IL (1) IL59158A (en)
IT (1) IT1143960B (en)
NL (2) NL190580C (en)
NO (2) NO154521C (en)
NZ (1) NZ192653A (en)
PH (1) PH17023A (en)
SE (1) SE448726B (en)
ZA (1) ZA80332B (en)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1053570C (en) 1987-10-07 2000-06-21 默尔多药物公司 Pharmaceutical composition for piperidinoalkanol-decongestant combination
AR240018A1 (en) * 1987-10-07 1990-01-31 Merrell Pharma Inc PROCEDURE FOR PREPARING A COMPOSITION THAT INCLUDES DERIVATIVES OF PIPERIDINOALCANOL.
US4929605A (en) * 1987-10-07 1990-05-29 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol derivatives
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
ZA90341B (en) * 1989-01-23 1990-10-31 Merrell Dow Pharma Liquid pharmaceutical composition for piperidinoalkanol derivatives
DE3917241A1 (en) * 1989-05-26 1990-11-29 Schaper & Bruemmer Gmbh 4- (HYDROXYDIPHENYLMETHYL) -1-PIPERIDYL-PHENYLALKANE DERIVATIVES
US5190029A (en) * 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US5182097A (en) * 1991-02-14 1993-01-26 Virginia Commonwealth University Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
TW198008B (en) * 1991-04-08 1993-01-11 Green Cross Corp
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
CA2129995C (en) * 1992-02-13 2000-04-11 Albert A. Carr Piperidinyl thiacyclic derivatives
US5631375A (en) * 1992-04-10 1997-05-20 Merrell Pharmaceuticals, Inc. Process for piperidine derivatives
AU671822B2 (en) * 1992-04-10 1996-09-12 Aventisub Ii Inc. 4-diphenylmethyl piperidine derivatives and process for their preparation
HU223774B1 (en) * 1992-05-11 2005-01-28 Merrell Dow Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
DE69334008T2 (en) † 1992-08-03 2006-10-19 Sepracor Inc., Marlborough Terfenadine carboxylate and the treatment of allergic diseases
US5654433A (en) * 1993-01-26 1997-08-05 Merrell Pharmaceuticals Inc. Process for piperidine derivatives
CA2147126C (en) * 1993-06-24 1999-08-24 Thomas E. D'ambra Piperidine derivatives and process for their production
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
US6147216A (en) * 1993-06-25 2000-11-14 Merrell Pharmaceuticals Inc. Intermediates useful for the preparation of antihistaminic piperidine derivatives
CA2166059C (en) * 1993-06-25 2005-08-16 Richard Carl Krauss Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
WO1995011677A1 (en) * 1993-10-25 1995-05-04 Merrell Pharmaceuticals Inc. A stable pharmaceutical composition of terfenadine and ibuprofen
WO1995031436A1 (en) * 1994-05-16 1995-11-23 Merrell Pharmaceuticals Inc. PROCESS AND DIASTEREOMERIC SALTS USEFUL FOR THE OPTICAL RESOLUTION OF RACEMIC α-[4-(1,1-DIMETHYLETHYL)PHENYL]-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINEBUTANOL AND DERIVATIVE COMPOUNDS
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
CN101497581B (en) * 1994-05-18 2012-07-11 安万特萨博Ⅱ有限公司 Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
CA2189007C (en) * 1994-05-18 2004-03-02 Daniel R. Henton Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
ATE177095T1 (en) 1994-08-25 1999-03-15 Merrell Pharma Inc SUBSTITUTED PIPERIDINE FOR THE TREATMENT OF ALLERGIC DISEASES
MX9706449A (en) * 1995-02-28 1997-11-29 Hoechst Marion Roussel Inc Pharmaceutical composition for piperidinoalkanol compounds.
HUP9801254A3 (en) * 1995-05-08 1998-09-28 Aventis Pharmaceuticals Inc Br Alpha-(substituted alkylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidine butanol derivatives, their preparation and their use as anti-histamines, anti-allergy agents and bronchodilators
US5574045A (en) * 1995-06-06 1996-11-12 Hoechst Marion Roussel, Inc. Oral pharmaceutical composition of piperidinoalkanol compounds in solution form
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
US6211199B1 (en) 1995-11-17 2001-04-03 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6201124B1 (en) * 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US6153754A (en) * 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5925761A (en) * 1997-02-04 1999-07-20 Sepracor Inc. Synthesis of terfenadine and derivatives
ATE260983T1 (en) * 1997-03-11 2004-03-15 Aventis Pharma Inc METHOD FOR PRODUCING 4-(4-(4-(HYDROXYDIPHENYL)-1-PIPERIDINYL)-1-HYDROXYBUTYL - ALPHA,ALPHA-DIMENTHYLPHENYLACETIC ACID AND PHOSPHORYLATED DERIVATIVES
US6451815B1 (en) 1997-08-14 2002-09-17 Aventis Pharmaceuticals Inc. Method of enhancing bioavailability of fexofenadine and its derivatives
WO1999009957A1 (en) * 1997-08-26 1999-03-04 Hoechst Marion Roussel, Inc. Pharmaceutical composition for combination of piperidinoalkanol-decongestant
ATE243191T1 (en) * 1997-12-17 2003-07-15 Aventis Pharma Gmbh METHOD FOR ALKYLATING ALKYL OR BENZYLCYANDER DERIVATIVES IN THE PRESENCE OF TRIALKYLAMINES OR PHOSPHINES
ID26390A (en) * 1997-12-23 2000-12-21 Schering Corp COMPOSITION FOR TREATMENT AND SKIN DISEASE CONCERNING FROM ONE LEAGOTRIENT ANTAGONIST AND ONE ANTIHISTAMINE
US6194431B1 (en) * 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
US6700012B2 (en) 1998-07-02 2004-03-02 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
US6683094B2 (en) 1998-07-02 2004-01-27 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
IL140649A0 (en) * 1998-07-02 2002-02-10 Aventis Pharma Inc Novel antihistaminic piperidine derivatives and intermediates for the preparation thereof
AU2007200674C1 (en) * 1998-07-02 2011-02-24 Aventisub Llc Novel antihistaminic piperidine derivatives and intermediates for the preparation thereof
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
IN191492B (en) * 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
US6613906B1 (en) * 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
CH695216A5 (en) * 2001-02-23 2006-01-31 Cilag Ag A method for manufacturing a non-hydrated salt of a piperidine derivative and a novel crystalline form thus obtainable of such a salt.
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
US20020177608A1 (en) * 2001-04-09 2002-11-28 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
EE200400010A (en) 2001-06-18 2004-02-16 Dr. Reddy's Laboratories Ltd. Novel crystalline forms of 4- [4- [4- (hydroxydiphenylmethyl) -1-piperidinyl] -1-hydroxybutyl] -α, α-dimethylbenzeneacetic acid and its hydrochloride
US7700779B2 (en) * 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
US20030158227A1 (en) * 2001-11-08 2003-08-21 Barnaba Krochmal Polymorphs of fexofenadine base
CA2465913A1 (en) * 2001-11-08 2003-05-15 Judith Aronhime Polymorphs of fexofenadine base
US6723348B2 (en) * 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
JP4625637B2 (en) 2002-02-22 2011-02-02 シャイア エルエルシー Active substance delivery system and method for protecting and administering an active substance
DE03757471T1 (en) * 2002-06-10 2005-09-01 Teva Pharmaceutical Industries Ltd. POLYMORPH FORM XVI OF FEXOFENADINE HYDROCHLORIDE
BR0317364A (en) * 2002-12-16 2005-11-16 Ranbaxy Lab Ltd Process for the preparation of fexofenadine
WO2004067511A1 (en) * 2003-01-31 2004-08-12 Ranbaxy Laboratories Limited Process for the preparation of fexofenadine
US20050065183A1 (en) * 2003-07-31 2005-03-24 Indranil Nandi Fexofenadine composition and process for preparing
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
GB0319935D0 (en) * 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
CA2560882A1 (en) * 2004-04-26 2005-11-03 Teva Pharmaceutical Industries Ltd. Crystalline forms of fexofenadine hydrochloride and processes for their preparation
WO2006008567A1 (en) * 2004-06-18 2006-01-26 Wockhardt Limited Pharmaceutical compositions for piperidinoalkanol compounds
ITMI20041568A1 (en) * 2004-07-30 2004-10-30 Dipharma Spa "BASE FEXOFENADINA POLYMORPHS"
US7498345B2 (en) * 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US7498443B2 (en) * 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of carebastine
JP2008514641A (en) * 2004-09-28 2008-05-08 テバ ファーマシューティカル インダストリーズ リミティド Crystalline fexofenadine and method for its preparation
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) * 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
PL2522365T3 (en) 2004-11-24 2017-05-31 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
JP2008120684A (en) * 2005-03-07 2008-05-29 Kumamoto Univ Antiallergic drug
WO2007017905A1 (en) * 2005-08-05 2007-02-15 Lupin Limited Oral pharmaceutical suspension compositions of fexofenadine
US20070088065A1 (en) * 2005-10-14 2007-04-19 Jie Du Metaxalone products, method of manufacture, and method of use
US20080292584A1 (en) * 2005-10-14 2008-11-27 Mutual Pharmaceutical Company, Inc. Metaxalone products, method of manufacture, and method of use
WO2007049303A2 (en) * 2005-10-28 2007-05-03 Ind-Swift Laboratories Limited An improved process for the preparation of highly pure fexofenadine
RU2008122978A (en) 2005-11-09 2009-12-20 Комбинаторкс, Инкорпорейтед (Us) METHODS, COMPOSITIONS AND KITS FOR TREATMENT OF MEDICAL CONDITIONS
DOP2006000274A (en) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc FEXOFENADINE SUSPENSION FORMULATION
CN100443470C (en) * 2006-07-21 2008-12-17 杭州保灵有限公司 Prepn of ebastine
ITMI20061492A1 (en) * 2006-07-27 2008-01-28 Archimica Srl PROCESS FOR THE PREPARATION OF FEXOPHENADINE.
ITMI20061491A1 (en) * 2006-07-27 2008-01-28 Archimica Srl PROCESS FOR THE PREPARATION OF FEXOPHENADINE.
US20080161324A1 (en) * 2006-09-14 2008-07-03 Johansen Lisa M Compositions and methods for treatment of viral diseases
CA2874595A1 (en) 2007-04-13 2009-02-19 Southern Research Institute Use of terfenadine for treating breast and ovarian tumors
ITMI20070987A1 (en) * 2007-05-16 2008-11-17 Dipharma Francis Srl PROCEDURE FOR THE PREPARATION OF KETONIC COMPOUNDS
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
EP2105134A1 (en) 2008-03-24 2009-09-30 Ranbaxy Laboratories Limited Stable amorphous fexofenadine hydrochloride
KR20110017365A (en) * 2008-05-30 2011-02-21 페어필드 클리니컬 트라이얼즈 엘엘씨 Method and composition for skin inflammation and discoloration
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
CN101585805B (en) * 2009-06-06 2011-07-06 浙江大学宁波理工学院 Preparation method of an antiallergic agent fexofenadine hydrochloride
EP2289867A3 (en) 2009-08-19 2012-04-25 Jubilant Organosys Limited A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof
CN101671292B (en) * 2009-10-10 2011-09-07 浙江大学宁波理工学院 Synthetic method of fexofenadine hydrochloride
US20110130711A1 (en) * 2009-11-19 2011-06-02 Follica, Inc. Hair growth treatment
EP2371817A1 (en) * 2010-04-01 2011-10-05 Arevipharma GmbH Process for the preparation of 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone and acid addition salts thereof
WO2011158262A1 (en) 2010-06-15 2011-12-22 Chemelectiva S.R.L. Polymorphic form of fexofenadine hydrochloride, intermediates and process for its preparation
KR20140030267A (en) 2011-05-23 2014-03-11 사노피 Process for the preparation of deuterated compounds containing n-alkyl groups
AR088204A1 (en) 2011-09-29 2014-05-14 Shionogi & Co MEDICINES FOR THE TREATMENT OF ALLERGY RHINITIS THAT INCLUDE A PGD2 ANTAGONIST AND A HISTAMINE ANTAGONIST
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
CN102659667B (en) * 2012-04-20 2013-08-14 浙江启明药业有限公司 Synthetic method of fexofenadine intermediate
CN103333100B (en) * 2013-06-06 2016-04-06 池州东升药业有限公司 A kind of synthesis technique of fexofenadine hydrochloride
ITMI20131652A1 (en) 2013-10-07 2015-04-08 Dipharma Francis Srl PROCEDURE FOR THE PURIFICATION OF DERIVATIVES OF 2-PHENYL-2-METHYL-PROPANOIC ACID
CN104557671B (en) * 2013-10-10 2018-04-13 池州东升药业有限公司 A kind of synthetic method of fexofenadine and intermediate
EP2949321A1 (en) 2014-05-26 2015-12-02 Sanovel Ilac Sanayi ve Ticaret A.S. Multilayer formulations of fexofenadine and montelukast
RS58961B1 (en) 2015-01-22 2019-08-30 Sanofi Aventis Deutschland Process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile
HUE047669T2 (en) 2015-10-22 2020-05-28 Sanofi Aventis Deutschland Process for the preparation of fexofenadine and of intermediates used therein
GB202212656D0 (en) 2022-08-31 2022-10-12 Novumgen Ltd An orodispersible tablet of fecofenadine and it process of preparation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242169A (en) * 1969-04-09 1971-08-11 Ucb Sa Piperidine derivatives
BE794598A (en) * 1972-01-28 1973-05-16 Richardson Merrell Inc NEW OLEFINIC DERIVATIVES OF PIPERIDINES SUBSTITUTED IN 4 AND THEIR PREPARATION PROCESS
BE794596A (en) * 1972-01-28 1973-05-16 Richardson Merrell Inc SUBSTITUTED PIPERIDINOALCANONE OXIMES AND THEIR PREPARATION PROCESS
US3806526A (en) * 1972-01-28 1974-04-23 Richardson Merrell Inc 1-aroylalkyl-4-diphenylmethyl piperidines
US3878217A (en) * 1972-01-28 1975-04-15 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
ZA728544B (en) * 1972-01-28 1974-02-27 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
US3965257A (en) * 1972-01-28 1976-06-22 Richardson-Merrell Inc. Compositions and methods for the treatment of the symptoms of histamine induced allergic reactions
US3931197A (en) * 1974-02-08 1976-01-06 Richardson-Merrell Inc. Substituted piperidine derivatives
US3941795A (en) * 1974-02-08 1976-03-02 Richardson-Merrell Inc. α-ARYL-4-SUBSTITUTED PIPERIDINOALKANOL DERIVATIVES
US3946022A (en) * 1974-03-04 1976-03-23 Richardson-Merrell Inc. Piperidine derivatives
US3922276A (en) * 1974-12-11 1975-11-25 Robins Co Inc A H 1-Substituted-4-benzylidenepiperidines
US3956296A (en) * 1974-12-11 1976-05-11 A. H. Robins Company, Incorporated 1-Substituted-4-benzylpiperidines

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DK153709B (en) 1988-08-22
NL980013I1 (en) 1998-06-02
JPH0132823B2 (en) 1989-07-10
FR2453854B1 (en) 1983-06-24
IT8048245A0 (en) 1980-03-24
SE448726B (en) 1987-03-16
CA1123438A (en) 1982-05-11
BE882703A (en) 1980-07-31
NL8000754A (en) 1980-10-14
FR2453854A1 (en) 1980-11-07
ATA144880A (en) 1984-03-15
JPS55141469A (en) 1980-11-05
ES489934A0 (en) 1981-03-16
ES8103735A1 (en) 1981-03-16
PH17023A (en) 1984-05-11
IT1143960B (en) 1986-10-29
NZ192653A (en) 1982-03-16
NL980013I2 (en) 1998-10-01
IL59158A (en) 1984-04-30
DE3007498A1 (en) 1980-10-23
DK132980A (en) 1980-10-11
DK153709C (en) 1988-12-27
DE3007498C2 (en) 1989-09-07
NL190580C (en) 1994-05-02
NO154521C (en) 1986-10-08
AT376208B (en) 1984-10-25
NL190580B (en) 1993-12-01
AU5501680A (en) 1980-10-16
IL59158A0 (en) 1980-05-30
NO154521B (en) 1986-06-30
NO1998017I1 (en) 1998-05-29
US4254129A (en) 1981-03-03
SE8002634L (en) 1980-10-11
ZA80332B (en) 1981-01-28
CH643245A5 (en) 1984-05-30
AU531146B2 (en) 1983-08-11

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