NO1998017I1 - Fexofenadine - Google Patents

Fexofenadine

Info

Publication number
NO1998017I1
NO1998017I1 NO1998017C NO1998017C NO1998017I1 NO 1998017 I1 NO1998017 I1 NO 1998017I1 NO 1998017 C NO1998017 C NO 1998017C NO 1998017 C NO1998017 C NO 1998017C NO 1998017 I1 NO1998017 I1 NO 1998017I1
Authority
NO
Norway
Prior art keywords
fexofenadine
Prior art date
Application number
NO1998017C
Other languages
Norwegian (no)
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21845568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO1998017(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of NO1998017I1 publication Critical patent/NO1998017I1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO1998017C 1979-04-10 1998-05-29 Fexofenadine NO1998017I1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/028,813 US4254129A (en) 1979-04-10 1979-04-10 Piperidine derivatives

Publications (1)

Publication Number Publication Date
NO1998017I1 true NO1998017I1 (en) 1998-05-29

Family

ID=21845568

Family Applications (2)

Application Number Title Priority Date Filing Date
NO801014A NO154521C (en) 1979-04-10 1980-04-09 ANALOGY PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE PIPERIDE INGREDIENTS.
NO1998017C NO1998017I1 (en) 1979-04-10 1998-05-29 Fexofenadine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO801014A NO154521C (en) 1979-04-10 1980-04-09 ANALOGY PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE PIPERIDE INGREDIENTS.

Country Status (19)

Country Link
US (1) US4254129A (en)
JP (1) JPS55141469A (en)
AT (1) AT376208B (en)
AU (1) AU531146B2 (en)
BE (1) BE882703A (en)
CA (1) CA1123438A (en)
CH (1) CH643245A5 (en)
DE (1) DE3007498A1 (en)
DK (1) DK153709C (en)
ES (1) ES489934A0 (en)
FR (1) FR2453854A1 (en)
IL (1) IL59158A (en)
IT (1) IT1143960B (en)
NL (2) NL190580C (en)
NO (2) NO154521C (en)
NZ (1) NZ192653A (en)
PH (1) PH17023A (en)
SE (1) SE448726B (en)
ZA (1) ZA80332B (en)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1053570C (en) 1987-10-07 2000-06-21 默尔多药物公司 Pharmaceutical composition for piperidinoalkanol-decongestant combination
US4929605A (en) * 1987-10-07 1990-05-29 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol derivatives
AR240018A1 (en) * 1987-10-07 1990-01-31 Merrell Pharma Inc PROCEDURE FOR PREPARING A COMPOSITION THAT INCLUDES DERIVATIVES OF PIPERIDINOALCANOL.
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
ZA90341B (en) * 1989-01-23 1990-10-31 Merrell Dow Pharma Liquid pharmaceutical composition for piperidinoalkanol derivatives
DE3917241A1 (en) * 1989-05-26 1990-11-29 Schaper & Bruemmer Gmbh 4- (HYDROXYDIPHENYLMETHYL) -1-PIPERIDYL-PHENYLALKANE DERIVATIVES
US5190029A (en) * 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US5182097A (en) * 1991-02-14 1993-01-26 Virginia Commonwealth University Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
TW198008B (en) * 1991-04-08 1993-01-11 Green Cross Corp
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
PT626968E (en) * 1992-02-13 2002-03-28 Merrell Pharma Inc TIACICLIC PIPERIDINYL DERIVATIVES
MX9302076A (en) * 1992-04-10 1994-03-31 Merrell Dow Pharma A NEW PROCESS TO PREPARE PIPERIDINE DERIVATIVES.
US5631375A (en) * 1992-04-10 1997-05-20 Merrell Pharmaceuticals, Inc. Process for piperidine derivatives
DE69320952T2 (en) * 1992-05-11 1999-05-27 Merrell Pharma Inc USE OF TERFENADINE DERIVATIVES AS AN ANTIHISTAMINICS IN LIVER DISEASE PATIENTS
RO116043B1 (en) * 1992-08-03 2000-10-30 Sepracor Inc Pharmaceutical composition
US5654433A (en) * 1993-01-26 1997-08-05 Merrell Pharmaceuticals Inc. Process for piperidine derivatives
US20020007068A1 (en) * 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
WO1995000482A1 (en) * 1993-06-24 1995-01-05 Albany Molecular Research, Inc. Piperidine derivatives and process for their production
US6147216A (en) * 1993-06-25 2000-11-14 Merrell Pharmaceuticals Inc. Intermediates useful for the preparation of antihistaminic piperidine derivatives
CN1159277C (en) 1993-06-25 2004-07-28 默里尔药物公司 New intermediate for preparation of anti-histamine piperidine derivatives
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
HU222887B1 (en) * 1993-10-25 2003-12-29 Merrell Pharmaceuticals Inc. A stable pharmaceutical composition of terfenadine and ibuprofen
CA2189000C (en) * 1994-05-16 2002-08-13 Mitsuo Nakamura Process and diastereomeric salts useful for the optical resolution of racemic .alpha.-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol and derivative compounds
CN101337922A (en) * 1994-05-18 2009-01-07 阿温蒂斯药物公司 Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
AU693892B2 (en) * 1994-05-18 1998-07-09 Aventisub Ii Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
CN1067385C (en) 1994-08-25 2001-06-20 默里尔药物公司 Novel substituted piperidines useful for the treatment of allergic diseases
DE69624559T2 (en) * 1995-02-28 2003-07-10 Aventis Pharma Inc MEDICINAL PREPARATIONS FOR PIPERIDINAL CANOL DERIVATIVES
KR19990008406A (en) * 1995-05-08 1999-01-25 스티븐엘.네스비트 Alpha- (substituted alkylphenyl) -4- (hydroxydiphenylmethyl) -1-piperidine butanol derivatives, methods of their preparation and their use as antihistamines, anti-allergic and bronchial dilators
US5574045A (en) * 1995-06-06 1996-11-12 Hoechst Marion Roussel, Inc. Oral pharmaceutical composition of piperidinoalkanol compounds in solution form
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
US6211199B1 (en) 1995-11-17 2001-04-03 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6153754A (en) 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US6201124B1 (en) 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5925761A (en) * 1997-02-04 1999-07-20 Sepracor Inc. Synthesis of terfenadine and derivatives
PT864653E (en) * 1997-03-11 2004-08-31 Aventis Pharma Inc PROCESS FOR PREPARATION OF 4- (4- (4- (HYDROXIDIFENYL) -1-PIPERIDINYL) -1-HYDROXIBUTIL) -ALFA, ALPHA-DIMETHYLPHENYL ACETATE AND PHOSPHORYLED DERIVATIVES
US6451815B1 (en) 1997-08-14 2002-09-17 Aventis Pharmaceuticals Inc. Method of enhancing bioavailability of fexofenadine and its derivatives
KR100514264B1 (en) * 1997-08-26 2005-09-15 아벤티스 파마슈티칼스 인크. Pharmaceutical Composition For Combination Of Piperidinoalkanol-Decongestant
ATE243191T1 (en) * 1997-12-17 2003-07-15 Aventis Pharma Gmbh METHOD FOR ALKYLATING ALKYL OR BENZYLCYANDER DERIVATIVES IN THE PRESENCE OF TRIALKYLAMINES OR PHOSPHINES
WO1999032125A1 (en) * 1997-12-23 1999-07-01 Schering Corporation Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine
US6194431B1 (en) * 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
US6683094B2 (en) 1998-07-02 2004-01-27 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
AU2007200674C1 (en) * 1998-07-02 2011-02-24 Aventisub Llc Novel antihistaminic piperidine derivatives and intermediates for the preparation thereof
US6689898B2 (en) 1998-07-02 2004-02-10 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
DK1091938T3 (en) * 1998-07-02 2011-02-07 Aventisub Ii Inc Antihistamine piperidine derivatives and intermediates for their preparation
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
IN191492B (en) * 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
US6613906B1 (en) * 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
CH695216A5 (en) * 2001-02-23 2006-01-31 Cilag Ag A method for manufacturing a non-hydrated salt of a piperidine derivative and a novel crystalline form thus obtainable of such a salt.
CA2444456A1 (en) * 2001-04-09 2002-10-17 Teva Pharmaceutical Industries Ltd. Polymorphs of fexofenadine hydrochloride
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
EP2261209A1 (en) 2001-06-18 2010-12-15 Dr. Reddy's Laboratories Ltd. Novel crystalline forms of 4-[4-[4- hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-alpha, alpha-dimethylbenene acetic acid and its hydrochloride
US7700779B2 (en) 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
US20030158227A1 (en) * 2001-11-08 2003-08-21 Barnaba Krochmal Polymorphs of fexofenadine base
WO2003039482A2 (en) * 2001-11-08 2003-05-15 Teva Pharmaceutical Industries Ltd. Polymorphs of fexofenadine base
US6723348B2 (en) * 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
AU2003217676B2 (en) 2002-02-22 2009-06-11 Takeda Pharmaceutical Company Limited Active agent delivery systems and methods for protecting and administering active agents
WO2003104197A1 (en) * 2002-06-10 2003-12-18 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
US20060173042A1 (en) * 2002-12-16 2006-08-03 Sharma Mukesh K Process for the preparation of fexofenadine
CN1756743A (en) * 2003-01-31 2006-04-05 兰贝克赛实验室有限公司 Process for the preparation of fexofenadine
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
US20050065183A1 (en) * 2003-07-31 2005-03-24 Indranil Nandi Fexofenadine composition and process for preparing
GB0319935D0 (en) * 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
MXPA06012281A (en) * 2004-04-26 2007-07-18 Teva Pharma Crystalline forms of fexofenadine hydrochloride and processes for their preparation.
WO2006008567A1 (en) * 2004-06-18 2006-01-26 Wockhardt Limited Pharmaceutical compositions for piperidinoalkanol compounds
ITMI20041568A1 (en) * 2004-07-30 2004-10-30 Dipharma Spa "BASE FEXOFENADINA POLYMORPHS"
US7498443B2 (en) * 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of carebastine
US7498345B2 (en) * 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of piperidine derivatives
EP1685106A2 (en) * 2004-09-28 2006-08-02 Teva Pharmaceutical Industries, Inc. Fexofendadine crystal form and processes for its preparation thereof
US20070020330A1 (en) * 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
ES2704482T3 (en) 2004-11-24 2019-03-18 Meda Pharmaceuticals Inc Compositions comprising azelastine and its methods of use
JP2008120684A (en) * 2005-03-07 2008-05-29 Kumamoto Univ Antiallergic drug
WO2007017905A1 (en) * 2005-08-05 2007-02-15 Lupin Limited Oral pharmaceutical suspension compositions of fexofenadine
US20080292584A1 (en) * 2005-10-14 2008-11-27 Mutual Pharmaceutical Company, Inc. Metaxalone products, method of manufacture, and method of use
US20070088065A1 (en) * 2005-10-14 2007-04-19 Jie Du Metaxalone products, method of manufacture, and method of use
WO2007049303A2 (en) * 2005-10-28 2007-05-03 Ind-Swift Laboratories Limited An improved process for the preparation of highly pure fexofenadine
CA2628570A1 (en) 2005-11-09 2007-05-18 Combinatorx, Incorporated Methods, compositions, and kits for the treatment of medical conditions
DOP2006000274A (en) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc FEXOFENADINE SUSPENSION FORMULATION
CN100443470C (en) * 2006-07-21 2008-12-17 杭州保灵有限公司 Prepn of ebastine
ITMI20061492A1 (en) * 2006-07-27 2008-01-28 Archimica Srl PROCESS FOR THE PREPARATION OF FEXOPHENADINE.
ITMI20061491A1 (en) * 2006-07-27 2008-01-28 Archimica Srl PROCESS FOR THE PREPARATION OF FEXOPHENADINE.
US20080161324A1 (en) * 2006-09-14 2008-07-03 Johansen Lisa M Compositions and methods for treatment of viral diseases
EP2420239B1 (en) 2007-04-13 2015-01-14 Southern Research Institute Clomipramine as anti-angiogenic agent
ITMI20070987A1 (en) * 2007-05-16 2008-11-17 Dipharma Francis Srl PROCEDURE FOR THE PREPARATION OF KETONIC COMPOUNDS
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
US20090306135A1 (en) 2008-03-24 2009-12-10 Mukesh Kumar Sharma Stable amorphous fexofenadine hydrochloride
AU2009251743A1 (en) * 2008-05-30 2009-12-03 Fairfield Clinical Trials, Llc Method and composition for skin inflammation and discoloration
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
CN101585805B (en) * 2009-06-06 2011-07-06 浙江大学宁波理工学院 Preparation method of an antiallergic agent fexofenadine hydrochloride
EP2289867A3 (en) 2009-08-19 2012-04-25 Jubilant Organosys Limited A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof
CN101671292B (en) * 2009-10-10 2011-09-07 浙江大学宁波理工学院 Synthetic method of fexofenadine hydrochloride
US20110130711A1 (en) * 2009-11-19 2011-06-02 Follica, Inc. Hair growth treatment
EP2371817A1 (en) * 2010-04-01 2011-10-05 Arevipharma GmbH Process for the preparation of 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone and acid addition salts thereof
US9216955B2 (en) 2010-06-15 2015-12-22 Chemelectiva S.R.L. Polymorphic form of Fexofenadine hydrochloride, intermediates and process for its preparation
CN103702961A (en) 2011-05-23 2014-04-02 赛诺菲 Process for the preparation of deuterated compounds containing n-alkyl groups
TW201318624A (en) 2011-09-29 2013-05-16 Shionogi & Co Drug for the treatment of allergic rhinitis comprising pgd2 antagonist and histamine antagonist
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
CN102659667B (en) * 2012-04-20 2013-08-14 浙江启明药业有限公司 Synthetic method of fexofenadine intermediate
CN103333100B (en) * 2013-06-06 2016-04-06 池州东升药业有限公司 A kind of synthesis technique of fexofenadine hydrochloride
ITMI20131652A1 (en) 2013-10-07 2015-04-08 Dipharma Francis Srl PROCEDURE FOR THE PURIFICATION OF DERIVATIVES OF 2-PHENYL-2-METHYL-PROPANOIC ACID
CN104557671B (en) * 2013-10-10 2018-04-13 池州东升药业有限公司 A kind of synthetic method of fexofenadine and intermediate
EP2949321A1 (en) 2014-05-26 2015-12-02 Sanovel Ilac Sanayi ve Ticaret A.S. Multilayer formulations of fexofenadine and montelukast
HUE044642T2 (en) 2015-01-22 2019-11-28 Sanofi Aventis Deutschland Process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile
ES2770341T3 (en) 2015-10-22 2020-07-01 Sanofi Aventis Deutschland Process for the preparation of fexofenadine and the intermediates used in it
GB202212656D0 (en) 2022-08-31 2022-10-12 Novumgen Ltd An orodispersible tablet of fecofenadine and it process of preparation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242169A (en) * 1969-04-09 1971-08-11 Ucb Sa Piperidine derivatives
BE794596A (en) * 1972-01-28 1973-05-16 Richardson Merrell Inc SUBSTITUTED PIPERIDINOALCANONE OXIMES AND THEIR PREPARATION PROCESS
BE794598A (en) * 1972-01-28 1973-05-16 Richardson Merrell Inc NEW OLEFINIC DERIVATIVES OF PIPERIDINES SUBSTITUTED IN 4 AND THEIR PREPARATION PROCESS
US3806526A (en) * 1972-01-28 1974-04-23 Richardson Merrell Inc 1-aroylalkyl-4-diphenylmethyl piperidines
ZA728544B (en) * 1972-01-28 1974-02-27 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
US3878217A (en) * 1972-01-28 1975-04-15 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
US3965257A (en) * 1972-01-28 1976-06-22 Richardson-Merrell Inc. Compositions and methods for the treatment of the symptoms of histamine induced allergic reactions
US3931197A (en) * 1974-02-08 1976-01-06 Richardson-Merrell Inc. Substituted piperidine derivatives
US3941795A (en) * 1974-02-08 1976-03-02 Richardson-Merrell Inc. α-ARYL-4-SUBSTITUTED PIPERIDINOALKANOL DERIVATIVES
US3946022A (en) * 1974-03-04 1976-03-23 Richardson-Merrell Inc. Piperidine derivatives
US3922276A (en) * 1974-12-11 1975-11-25 Robins Co Inc A H 1-Substituted-4-benzylidenepiperidines
US3956296A (en) * 1974-12-11 1976-05-11 A. H. Robins Company, Incorporated 1-Substituted-4-benzylpiperidines

Also Published As

Publication number Publication date
NO154521B (en) 1986-06-30
NL190580B (en) 1993-12-01
NO801014L (en) 1980-10-13
AT376208B (en) 1984-10-25
DE3007498A1 (en) 1980-10-23
DK153709C (en) 1988-12-27
SE8002634L (en) 1980-10-11
NZ192653A (en) 1982-03-16
ES8103735A1 (en) 1981-03-16
DK132980A (en) 1980-10-11
CH643245A5 (en) 1984-05-30
JPS55141469A (en) 1980-11-05
AU531146B2 (en) 1983-08-11
BE882703A (en) 1980-07-31
NL980013I1 (en) 1998-06-02
ZA80332B (en) 1981-01-28
SE448726B (en) 1987-03-16
NL980013I2 (en) 1998-10-01
NL8000754A (en) 1980-10-14
NO154521C (en) 1986-10-08
IT8048245A0 (en) 1980-03-24
ES489934A0 (en) 1981-03-16
DE3007498C2 (en) 1989-09-07
CA1123438A (en) 1982-05-11
PH17023A (en) 1984-05-11
IT1143960B (en) 1986-10-29
ATA144880A (en) 1984-03-15
AU5501680A (en) 1980-10-16
IL59158A0 (en) 1980-05-30
IL59158A (en) 1984-04-30
NL190580C (en) 1994-05-02
FR2453854B1 (en) 1983-06-24
JPH0132823B2 (en) 1989-07-10
FR2453854A1 (en) 1980-11-07
US4254129A (en) 1981-03-03
DK153709B (en) 1988-08-22

Similar Documents

Publication Publication Date Title
NO1998017I1 (en) Fexofenadine
FI803135L (en) IMIDAZODIAZEPIN-derivate
FI802358A (en) LAMINATMATERIAL
FI800790A (en) FJAERRVAERMEROER
FI800209A (en) LOCKTAONG
FI802122A (en) BRAENSLEPATRON AVSEDD FOER EN KOKARREAKTOR
AT363172B (en) MARKHOEHLENNAGEL
AT359315B (en) MICROHARDENER
FI802576A (en) FEKEREDNADSELEMENT FOER FASADYTOR
FI802119A (en) PARTIKELARTADE BLEKNINGSBLANDNINGAR
FI801104A (en) OELTILLVERKNING
AT369471B (en) FIRMWORK
FI800735A (en) 9-AMINOALKYLFLUORENER
FI800498A (en) EKOBOTTEN
FI801890A (en) AXELTAETNINGSRING
FI803488L (en) INLOPPSLAODA FOER VIRAPRESSAR
FI791906A (en) VEDKLAPPSHUGGARE
FI802943A (en) PIEZOELEKTRISK OMVANDLARE
FI801054A (en) RENINGSFOERFARANDE FOER URSODESOXYCOLSYRA
FI800369A (en) METALLPROFILSTAONG
AT364180B (en) DIARAEHMCHEN
FI802008A (en) BENSIMIDAZOLDERIVAT
FI802450A (en) SKOERDETROESKA
FI800983A (en) couplingThis
FI800533A (en) BILDROER FOER FAERGTELEVISION