NO335602B1 - Farmasøytisk sammensetning for nedregulering av amyloid inneholdende et immunogen omfattende en polyaminosyre som induserer produksjon av antistoff mot dyrets autologe amyloid forløperprotein (APP) eller amyloid-beta (A-beta), nukleinsyrefragment kodende for polyaminosyren, vektor og transformert celle. - Google Patents

Farmasøytisk sammensetning for nedregulering av amyloid inneholdende et immunogen omfattende en polyaminosyre som induserer produksjon av antistoff mot dyrets autologe amyloid forløperprotein (APP) eller amyloid-beta (A-beta), nukleinsyrefragment kodende for polyaminosyren, vektor og transformert celle. Download PDF

Info

Publication number
NO335602B1
NO335602B1 NO20040431A NO20040431A NO335602B1 NO 335602 B1 NO335602 B1 NO 335602B1 NO 20040431 A NO20040431 A NO 20040431A NO 20040431 A NO20040431 A NO 20040431A NO 335602 B1 NO335602 B1 NO 335602B1
Authority
NO
Norway
Prior art keywords
app
amino acid
cell
amyloid
nucleic acid
Prior art date
Application number
NO20040431A
Other languages
English (en)
Norwegian (no)
Other versions
NO20040431L (no
Inventor
Martin Roland Jensen
Klaus Gregorius Nielsen
Peter Birk Rasmussen
Peter Koefoed
Florence Dal Degan
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2002/000547 external-priority patent/WO2003015812A2/en
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20040431L publication Critical patent/NO20040431L/no
Publication of NO335602B1 publication Critical patent/NO335602B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087Polysaccharides; Lipopolysaccharides [LPS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/64Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
NO20040431A 2001-08-20 2004-01-30 Farmasøytisk sammensetning for nedregulering av amyloid inneholdende et immunogen omfattende en polyaminosyre som induserer produksjon av antistoff mot dyrets autologe amyloid forløperprotein (APP) eller amyloid-beta (A-beta), nukleinsyrefragment kodende for polyaminosyren, vektor og transformert celle. NO335602B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101231 2001-08-20
PCT/DK2002/000547 WO2003015812A2 (en) 2001-08-20 2002-08-20 Beta-amyloid-analogue-t-cell epitop vaccine

Publications (2)

Publication Number Publication Date
NO20040431L NO20040431L (no) 2004-04-16
NO335602B1 true NO335602B1 (no) 2015-01-12

Family

ID=35160895

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20040431A NO335602B1 (no) 2001-08-20 2004-01-30 Farmasøytisk sammensetning for nedregulering av amyloid inneholdende et immunogen omfattende en polyaminosyre som induserer produksjon av antistoff mot dyrets autologe amyloid forløperprotein (APP) eller amyloid-beta (A-beta), nukleinsyrefragment kodende for polyaminosyren, vektor og transformert celle.

Country Status (10)

Country Link
EP (1) EP1363664A2 (https=)
JP (1) JP2004529881A (https=)
CN (1) CN100562338C (https=)
AU (1) AU2002233166B2 (https=)
CA (1) CA2440197A1 (https=)
IL (1) IL157475A0 (https=)
NO (1) NO335602B1 (https=)
NZ (1) NZ527720A (https=)
WO (1) WO2002066056A2 (https=)
ZA (1) ZA200400895B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1539232A1 (en) * 2002-09-12 2005-06-15 Pharmexa A/S Immunization against autologous ghrelin
AU2004281634B2 (en) * 2003-09-03 2011-01-27 Dendritherapeutics, Inc. Multiplex vaccines
CA2545152A1 (en) * 2003-11-07 2005-05-26 Howard J. Federoff Compositions and methods of treating neurological diseases
US20120231044A1 (en) * 2011-03-11 2012-09-13 Flow Pharma, Inc. Vaccine formulation of mannose coated peptide particles
CN103665113A (zh) * 2012-09-14 2014-03-26 深圳市安群生物工程有限公司 人Aβ42抗原决定簇多肽、抗原、抗体、用途及试剂盒
RU2635517C1 (ru) * 2016-09-14 2017-11-13 Закрытое акционерное общество "Институт фармацевтических технологий" (ЗАО "ИФТ") Синтетический иммуноген для защиты и лечения от зависимости от психоактивных веществ
EP3773712A1 (en) 2018-04-10 2021-02-17 AC Immune SA Anti-abeta therapeutic vaccines
CN112165956A (zh) * 2018-04-10 2021-01-01 Ac免疫有限公司 抗Aβ治疗性疫苗

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU685047B2 (en) * 1992-02-11 1998-01-15 Henry M. Jackson Foundation For The Advancement Of Military Medicine Dual carrier immunogenic construct
WO1993023076A1 (en) * 1992-05-20 1993-11-25 The Johns-Hopkins University Alternative receptor therapy
IL141868A0 (en) * 1998-10-05 2002-03-10 M & E Biotech As Novel methods for therapeutic vaccination

Also Published As

Publication number Publication date
CN1893970A (zh) 2007-01-10
NZ527720A (en) 2005-03-24
ZA200400895B (en) 2005-05-03
NO20040431L (no) 2004-04-16
CA2440197A1 (en) 2002-08-29
WO2002066056A3 (en) 2003-01-03
AU2002233166B2 (en) 2006-06-29
CN100562338C (zh) 2009-11-25
IL157475A0 (en) 2004-03-28
WO2002066056A2 (en) 2002-08-29
EP1363664A2 (en) 2003-11-26
WO2002066056A8 (en) 2004-04-29
JP2004529881A (ja) 2004-09-30

Similar Documents

Publication Publication Date Title
KR101057488B1 (ko) 베타-아밀로이드-유사체 - t-세포 에피토프 백신
JP5025871B2 (ja) アミロイドの新規なダウン−レギュレート方法
AU783144B2 (en) Novel method for down-regulation of amyloid
AU2002325199A1 (en) Beta-amyloid-analogue-T-cell epitop vaccine
NO335602B1 (no) Farmasøytisk sammensetning for nedregulering av amyloid inneholdende et immunogen omfattende en polyaminosyre som induserer produksjon av antistoff mot dyrets autologe amyloid forløperprotein (APP) eller amyloid-beta (A-beta), nukleinsyrefragment kodende for polyaminosyren, vektor og transformert celle.
HK1247081A1 (en) Novel method for down-regulation of amyloid
HK1064934B (en) Beta-amyloid-analogue - t-cell epitop vaccine
HK1096288A (en) Beta-amyloid-analogue-t-cell epitop vaccine
HK1089386A (en) Novel method for down-regulation of amyloid

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees