NO327854B1 - DNA-sekvens, replikerbar ekspresjonsvektor, transformert eukaryot eller prokaryot vertscelle; RAP-2 protein, isoform, fragment, funksjonell analog eller derivater derav samt fremgangsmate for fremstilling og anvendelse derav; farmasoytisk preparat, anvendelse av en rekombinant dyrevirusvektor og en vektor kodende for ribozym sekvens. - Google Patents

DNA-sekvens, replikerbar ekspresjonsvektor, transformert eukaryot eller prokaryot vertscelle; RAP-2 protein, isoform, fragment, funksjonell analog eller derivater derav samt fremgangsmate for fremstilling og anvendelse derav; farmasoytisk preparat, anvendelse av en rekombinant dyrevirusvektor og en vektor kodende for ribozym sekvens. Download PDF

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Publication number
NO327854B1
NO327854B1 NO20004649A NO20004649A NO327854B1 NO 327854 B1 NO327854 B1 NO 327854B1 NO 20004649 A NO20004649 A NO 20004649A NO 20004649 A NO20004649 A NO 20004649A NO 327854 B1 NO327854 B1 NO 327854B1
Authority
NO
Norway
Prior art keywords
rap
protein
sequence
cell
rip
Prior art date
Application number
NO20004649A
Other languages
English (en)
Norwegian (no)
Other versions
NO20004649L (no
NO20004649D0 (no
Inventor
David Wallach
Andrei Kovalenko
Marshall S Horwitz
Yongan Li
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12375898A external-priority patent/IL123758A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of NO20004649D0 publication Critical patent/NO20004649D0/no
Publication of NO20004649L publication Critical patent/NO20004649L/no
Publication of NO327854B1 publication Critical patent/NO327854B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Pain & Pain Management (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20004649A 1998-03-19 2000-09-18 DNA-sekvens, replikerbar ekspresjonsvektor, transformert eukaryot eller prokaryot vertscelle; RAP-2 protein, isoform, fragment, funksjonell analog eller derivater derav samt fremgangsmate for fremstilling og anvendelse derav; farmasoytisk preparat, anvendelse av en rekombinant dyrevirusvektor og en vektor kodende for ribozym sekvens. NO327854B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL12375898A IL123758A0 (en) 1998-03-19 1998-03-19 Modulators of the function of receptors of the TNF/NGF receptor family and other proteins
IL12602498A IL126024A0 (en) 1998-03-19 1998-09-01 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
PCT/IL1999/000158 WO1999047672A1 (en) 1998-03-19 1999-03-18 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
CA002323637A CA2323637A1 (en) 1998-03-19 1999-03-18 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins

Publications (3)

Publication Number Publication Date
NO20004649D0 NO20004649D0 (no) 2000-09-18
NO20004649L NO20004649L (no) 2000-10-30
NO327854B1 true NO327854B1 (no) 2009-10-05

Family

ID=39598416

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004649A NO327854B1 (no) 1998-03-19 2000-09-18 DNA-sekvens, replikerbar ekspresjonsvektor, transformert eukaryot eller prokaryot vertscelle; RAP-2 protein, isoform, fragment, funksjonell analog eller derivater derav samt fremgangsmate for fremstilling og anvendelse derav; farmasoytisk preparat, anvendelse av en rekombinant dyrevirusvektor og en vektor kodende for ribozym sekvens.

Country Status (24)

Country Link
US (1) US6734174B1 (xx)
EP (1) EP1062336B1 (xx)
JP (1) JP4351389B2 (xx)
KR (1) KR100748293B1 (xx)
CN (1) CN1232641C (xx)
AT (1) ATE318310T1 (xx)
AU (1) AU760900B2 (xx)
BG (2) BG64990B1 (xx)
BR (1) BR9909659A (xx)
CA (2) CA2323637A1 (xx)
DE (1) DE69929958T2 (xx)
DK (1) DK1062336T3 (xx)
EA (1) EA004062B1 (xx)
EE (1) EE200000538A (xx)
ES (1) ES2258838T3 (xx)
HK (1) HK1034995A1 (xx)
HU (1) HUP0101612A3 (xx)
IL (1) IL126024A0 (xx)
NO (1) NO327854B1 (xx)
NZ (2) NZ525566A (xx)
PL (1) PL200763B1 (xx)
PT (1) PT1062336E (xx)
SK (1) SK285804B6 (xx)
WO (1) WO1999047672A1 (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189832B1 (en) * 1998-08-20 2007-03-13 The Regents Of The University Of California Gamma subunit of cytokine responsive IκB-alpha kinase complex and methods of using same
US7745579B1 (en) 1998-09-01 2010-06-29 David Wallach Inhibitor of NF-KB activation
SG2011076551A (en) 2001-06-26 2015-08-28 Amgen Inc Antibodies to opgl
US7521534B1 (en) * 2003-03-03 2009-04-21 The University Board Of Regents Of Texas System IKK gamma gene products and methods for making and using same
US7700553B2 (en) 2003-09-24 2010-04-20 Institut Pasteur Selective inhibition of NF-κB activation by peptides designed to disrupt nemo oligomerization
JP5746191B2 (ja) 2009-10-19 2015-07-08 ハナル バイオファーマ カンパニーリミテッドHanAll Biopharma Co., Ltd. 修飾されたヒト腫瘍壊死因子受容体−1ポリペプチドまたはその断片及びその製造方法
CN102399819B (zh) * 2011-08-24 2013-06-19 西北农林科技大学 一种质粒型腺病毒载体pAd-NRIP1及其构建方法
DE102011115480A1 (de) * 2011-10-06 2013-04-11 Biostep Gmbh Substrat und Vorrichtung zur Chemilumineszenzdetektion
AR102981A1 (es) 2014-12-11 2017-04-05 Harvard College Inhibidores de la necrosis celular y métodos de preparación de los mismos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL73883A (en) * 1984-12-20 1990-12-23 Yeda Res & Dev Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha
IL94039A (en) * 1989-08-06 2006-09-05 Yeda Res & Dev Antibodies to tbp - 1 and their use
AU636608B2 (en) * 1989-05-18 1993-05-06 Yeda Research And Development Co. Ltd. Tumor necrosis factor binding protein II, it's purification and antibodies thereto
EP1588712A1 (en) * 1995-02-22 2005-10-26 Yeda Research & Development Company, Ltd. Modulators of regulatory proteins
US5674734A (en) * 1995-05-18 1997-10-07 President And Fellows Of Harvard College Cell death protein
AU7457796A (en) * 1995-10-23 1997-05-15 Tularik Inc. Rip: novel human protein involved in tumor necrosis factor signal transduction, and screening assays
EP0914338A2 (en) 1996-05-29 1999-05-12 Genzyme Corporation Cell growth regulatory genes

Also Published As

Publication number Publication date
WO1999047672A1 (en) 1999-09-23
PL343262A1 (en) 2001-07-30
US6734174B1 (en) 2004-05-11
CN1295614A (zh) 2001-05-16
NO20004649L (no) 2000-10-30
BG104769A (en) 2001-04-30
NO20004649D0 (no) 2000-09-18
IL126024A0 (en) 1999-05-09
CN1232641C (zh) 2005-12-21
ES2258838T3 (es) 2006-09-01
BG64990B1 (bg) 2006-11-30
ATE318310T1 (de) 2006-03-15
KR100748293B1 (ko) 2007-08-09
EA004062B1 (ru) 2003-12-25
CA2625284A1 (en) 1999-09-23
EA200000961A1 (ru) 2001-04-23
SK13762000A3 (sk) 2001-03-12
JP4351389B2 (ja) 2009-10-28
EE200000538A (et) 2002-04-15
BG109537A (en) 2007-11-30
AU760900B2 (en) 2003-05-22
DK1062336T3 (da) 2006-05-29
NZ525566A (en) 2004-12-24
HUP0101612A3 (en) 2005-03-29
PL200763B1 (pl) 2009-02-27
PT1062336E (pt) 2006-05-31
KR20050107527A (ko) 2005-11-11
JP2002506644A (ja) 2002-03-05
EP1062336A1 (en) 2000-12-27
AU2954599A (en) 1999-10-11
DE69929958T2 (de) 2006-11-23
BG65684B1 (bg) 2009-06-30
HUP0101612A2 (hu) 2004-01-28
EP1062336B1 (en) 2006-02-22
BR9909659A (pt) 2000-11-21
CA2323637A1 (en) 1999-09-23
SK285804B6 (sk) 2007-08-02
DE69929958D1 (de) 2006-04-27
NZ506776A (en) 2003-08-29
HK1034995A1 (en) 2001-11-09

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