NO319331B1 - Fremgangsmate for fremstilling av terapeutisk middel bestaende av antigenspesifikke, cytotoksiske T-celler. - Google Patents

Fremgangsmate for fremstilling av terapeutisk middel bestaende av antigenspesifikke, cytotoksiske T-celler. Download PDF

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Publication number
NO319331B1
NO319331B1 NO19964896A NO964896A NO319331B1 NO 319331 B1 NO319331 B1 NO 319331B1 NO 19964896 A NO19964896 A NO 19964896A NO 964896 A NO964896 A NO 964896A NO 319331 B1 NO319331 B1 NO 319331B1
Authority
NO
Norway
Prior art keywords
cells
antigen
ctl
vector
cell
Prior art date
Application number
NO19964896A
Other languages
English (en)
Norwegian (no)
Other versions
NO964896L (no
NO964896D0 (no
Inventor
Claudio Bordignon
Fulvio Mavilio
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of NO964896L publication Critical patent/NO964896L/no
Publication of NO964896D0 publication Critical patent/NO964896D0/no
Publication of NO319331B1 publication Critical patent/NO319331B1/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48Blood cells, e.g. leukemia or lymphoma
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO19964896A 1994-05-16 1996-11-18 Fremgangsmate for fremstilling av terapeutisk middel bestaende av antigenspesifikke, cytotoksiske T-celler. NO319331B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1994/001573 WO1995031208A1 (en) 1994-05-16 1994-05-16 Method of immunomodulation by means of adoptive transfer of antigen-specific cytotoxic t-cells

Publications (3)

Publication Number Publication Date
NO964896L NO964896L (no) 1996-11-18
NO964896D0 NO964896D0 (no) 1996-11-18
NO319331B1 true NO319331B1 (no) 2005-07-18

Family

ID=8165855

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19964896A NO319331B1 (no) 1994-05-16 1996-11-18 Fremgangsmate for fremstilling av terapeutisk middel bestaende av antigenspesifikke, cytotoksiske T-celler.

Country Status (11)

Country Link
EP (1) EP0804210B1 (da)
JP (1) JP3288708B2 (da)
KR (1) KR100219258B1 (da)
AT (1) ATE228368T1 (da)
AU (1) AU691501B2 (da)
DE (1) DE69431808T2 (da)
DK (1) DK0804210T3 (da)
ES (1) ES2186686T3 (da)
NO (1) NO319331B1 (da)
PT (1) PT804210E (da)
WO (1) WO1995031208A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063375A (en) * 1996-09-10 2000-05-16 Medical University Of South Carolina Semiallogeneic cell hybrids and related methods for treating cancer
GB0224442D0 (en) 2002-10-21 2002-11-27 Molmed Spa A delivery system
KR100882445B1 (ko) 2007-03-16 2009-02-09 울산대학교 산학협력단 항―4-1bb 항체를 이용한 항원 특이적 자가유래cd8+t 세포의 분리 및 증식 방법
EP3101122B1 (en) 2009-08-24 2023-06-14 Baylor College of Medicine Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses
GB201121308D0 (en) 2011-12-12 2012-01-25 Cell Medica Ltd Process
PL3591047T3 (pl) 2012-02-09 2022-12-05 Baylor College Of Medicine Mieszanki peptydowe do wytwarzania wielowirusowych ctl o szerokiej swoistości
EP3350600A4 (en) 2015-09-18 2019-04-17 Baylor College of Medicine DISTINCTION OF AN IMMUNOGENIC ANTIGEN OF A PATHOGEN AND CORRELATION WITH CLINICAL EFFECTIVENESS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992005262A1 (en) * 1990-09-14 1992-04-02 The John Hopkins University Methods and compositions for genetic therapy and potentiation of anti-tumor immunity
US5529774A (en) * 1991-08-13 1996-06-25 The Regents Of The University Of California In vivo transfer of the HSV-TK gene implanted retroviral producer cells

Also Published As

Publication number Publication date
DE69431808T2 (de) 2003-09-18
EP0804210B1 (en) 2002-11-27
DK0804210T3 (da) 2003-03-10
KR100219258B1 (ko) 1999-09-01
ES2186686T3 (es) 2003-05-16
JPH09507643A (ja) 1997-08-05
PT804210E (pt) 2003-04-30
EP0804210A1 (en) 1997-11-05
AU691501B2 (en) 1998-05-21
JP3288708B2 (ja) 2002-06-04
NO964896L (no) 1996-11-18
NO964896D0 (no) 1996-11-18
WO1995031208A1 (en) 1995-11-23
DE69431808D1 (de) 2003-01-09
ATE228368T1 (de) 2002-12-15
AU6928194A (en) 1995-12-05

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