NO308545B1 - FremgangsmÕte ved hurtig pÕvisning av soppinfeksjoner, samt et sett for bruk ved en slik fremgangsmÕte - Google Patents
FremgangsmÕte ved hurtig pÕvisning av soppinfeksjoner, samt et sett for bruk ved en slik fremgangsmÕte Download PDFInfo
- Publication number
- NO308545B1 NO308545B1 NO920993A NO920993A NO308545B1 NO 308545 B1 NO308545 B1 NO 308545B1 NO 920993 A NO920993 A NO 920993A NO 920993 A NO920993 A NO 920993A NO 308545 B1 NO308545 B1 NO 308545B1
- Authority
- NO
- Norway
- Prior art keywords
- peroxide
- color
- hydrogen peroxide
- component
- heavy metal
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 34
- 238000001514 detection method Methods 0.000 title claims description 5
- 206010017533 Fungal infection Diseases 0.000 title description 10
- 208000031888 Mycoses Diseases 0.000 title description 10
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 43
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 21
- 150000001875 compounds Chemical class 0.000 claims description 21
- 238000012360 testing method Methods 0.000 claims description 20
- 229910001385 heavy metal Inorganic materials 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 15
- 241000233866 Fungi Species 0.000 claims description 14
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 claims description 14
- 150000003839 salts Chemical class 0.000 claims description 14
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 claims description 14
- 150000002978 peroxides Chemical class 0.000 claims description 13
- 239000000243 solution Substances 0.000 claims description 13
- 108040007629 peroxidase activity proteins Proteins 0.000 claims description 12
- 239000000758 substrate Substances 0.000 claims description 11
- 239000007853 buffer solution Substances 0.000 claims description 10
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 claims description 7
- 102000003992 Peroxidases Human genes 0.000 claims description 7
- 229940074360 caffeic acid Drugs 0.000 claims description 7
- 235000004883 caffeic acid Nutrition 0.000 claims description 7
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 claims description 7
- MHUWZNTUIIFHAS-CLFAGFIQSA-N dioleoyl phosphatidic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(COP(O)(O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC MHUWZNTUIIFHAS-CLFAGFIQSA-N 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 7
- 229960004502 levodopa Drugs 0.000 claims description 7
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical group [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 6
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 6
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 5
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical group [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 5
- 239000000872 buffer Substances 0.000 claims description 5
- 239000002516 radical scavenger Substances 0.000 claims description 5
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 5
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 5
- 239000011545 carbonate/bicarbonate buffer Substances 0.000 claims description 3
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 3
- POECFFCNUXZPJT-UHFFFAOYSA-M sodium;carbonic acid;hydrogen carbonate Chemical compound [Na+].OC(O)=O.OC([O-])=O POECFFCNUXZPJT-UHFFFAOYSA-M 0.000 claims description 3
- 239000012266 salt solution Substances 0.000 claims description 2
- 230000002000 scavenging effect Effects 0.000 claims description 2
- 229960002163 hydrogen peroxide Drugs 0.000 claims 6
- 229960001484 edetic acid Drugs 0.000 claims 3
- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 claims 2
- 239000007791 liquid phase Substances 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 15
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 8
- 102000013415 peroxidase activity proteins Human genes 0.000 description 8
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 description 7
- 238000006243 chemical reaction Methods 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 6
- 244000005700 microbiome Species 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 241000222120 Candida <Saccharomycetales> Species 0.000 description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 4
- 239000004202 carbamide Substances 0.000 description 4
- 210000000214 mouth Anatomy 0.000 description 4
- 108700020962 Peroxidase Proteins 0.000 description 3
- 238000004061 bleaching Methods 0.000 description 3
- 230000002538 fungal effect Effects 0.000 description 3
- 239000002054 inoculum Substances 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 102000004400 Aminopeptidases Human genes 0.000 description 2
- 108090000915 Aminopeptidases Proteins 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 102000003896 Myeloperoxidases Human genes 0.000 description 2
- 108090000235 Myeloperoxidases Proteins 0.000 description 2
- 206010046914 Vaginal infection Diseases 0.000 description 2
- 201000008100 Vaginitis Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000000265 leukocyte Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 150000003668 tyrosines Chemical class 0.000 description 2
- ZGPHAZHLWWSPMV-UHFFFAOYSA-N 1-amino-3,4,5-trihydroxypentan-2-one Chemical compound NCC(=O)C(O)C(O)CO ZGPHAZHLWWSPMV-UHFFFAOYSA-N 0.000 description 1
- BDOYKFSQFYNPKF-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid;sodium Chemical compound [Na].[Na].OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O BDOYKFSQFYNPKF-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 238000008940 Alkaline Phosphatase assay kit Methods 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- 102100038609 Lactoperoxidase Human genes 0.000 description 1
- 108010023244 Lactoperoxidase Proteins 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 206010061372 Streptococcal infection Diseases 0.000 description 1
- 241001255854 Teras Species 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 210000003756 cervix mucus Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 1
- 229960005091 chloramphenicol Drugs 0.000 description 1
- 239000003593 chromogenic compound Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 229940057428 lactoperoxidase Drugs 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000002611 ovarian Effects 0.000 description 1
- 239000007793 ph indicator Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- BFPJYWDBBLZXOM-UHFFFAOYSA-L potassium tellurite Chemical compound [K+].[K+].[O-][Te]([O-])=O BFPJYWDBBLZXOM-UHFFFAOYSA-L 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229960004441 tyrosine Drugs 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 208000010484 vulvovaginitis Diseases 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/554,003 US5098830A (en) | 1990-07-16 | 1990-07-16 | Very rapid detection of fungal infections |
| PCT/US1991/004741 WO1992001373A1 (en) | 1990-07-16 | 1991-07-03 | Very rapid detection of fungal infections |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO920993D0 NO920993D0 (no) | 1992-03-13 |
| NO920993L NO920993L (no) | 1992-05-15 |
| NO308545B1 true NO308545B1 (no) | 2000-09-25 |
Family
ID=24211666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO920993A NO308545B1 (no) | 1990-07-16 | 1992-03-13 | FremgangsmÕte ved hurtig pÕvisning av soppinfeksjoner, samt et sett for bruk ved en slik fremgangsmÕte |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5098830A (de) |
| EP (1) | EP0491936B1 (de) |
| AU (1) | AU655594B2 (de) |
| CA (1) | CA2065401C (de) |
| DE (1) | DE69114457T2 (de) |
| ES (1) | ES2078538T3 (de) |
| MX (1) | MX9100216A (de) |
| NO (1) | NO308545B1 (de) |
| WO (1) | WO1992001373A1 (de) |
| ZA (1) | ZA915312B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9315440D0 (en) * | 1993-07-26 | 1993-09-08 | Cambridge Res & Innovation | An amine tester for diagnosing bacterial vaginosis and vaginitus |
| GB9510513D0 (en) * | 1994-12-16 | 1995-07-19 | Ind Gmbh | Determining the organic content of a fluid |
| EP0781850A3 (de) * | 1995-12-28 | 1998-08-12 | Mochida Pharmaceutical Co., Ltd. | Wasserstoffperoxid-Zusatz verwendendes Assay |
| GB9717209D0 (en) * | 1997-08-14 | 1997-10-22 | Aromascan Plc | Condition detector |
| GB9918945D0 (en) | 1999-08-12 | 1999-10-13 | Biocatalysts Ltd | Hydrogen peroxide monitoring |
| US6603403B2 (en) | 2000-12-12 | 2003-08-05 | Kimberly-Clark Worldwide, Inc. | Remote, wetness signaling system |
| US6583722B2 (en) | 2000-12-12 | 2003-06-24 | Kimberly-Clark Worldwide, Inc. | Wetness signaling device |
| US6494833B1 (en) | 2001-06-19 | 2002-12-17 | Welch Allyn, Inc. | Conditioning apparatus for a chemical sensing instrument |
| JP2005528887A (ja) * | 2002-01-31 | 2005-09-29 | エクスプレッシブ コンストラクツ，インコーポレイテッド | 微生物の検出方法 |
| AU2003291135A1 (en) * | 2002-11-26 | 2004-06-18 | Expressive Constructs, Inc. | Methods, biosensors and kits for detecting and identifying fungi |
| US20050042711A1 (en) * | 2003-08-11 | 2005-02-24 | George Mason University | Field test for fungi |
| DE602005011584D1 (de) * | 2004-03-22 | 2009-01-22 | Evonik Goldschmidt Gmbh | Verfahren und testkit zum nachweis und zur quantifizierung von organismen |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4021538A (en) * | 1975-09-29 | 1977-05-03 | Yu Ruey J | Method for producing pigmentation in hair or skin |
| US4140580A (en) * | 1976-05-03 | 1979-02-20 | Mcdonnell Douglas Corporation | Broth for indicating presence of candida yeast and other yeasts and fungi |
| US4874695A (en) * | 1983-03-08 | 1989-10-17 | American Home Products Corp. | Rapid indentification of yeast and other fungal microorganisms by enzyme detection |
| US4847128A (en) * | 1984-03-22 | 1989-07-11 | Wadley Technologies, Inc. | Miniaturized yeast identification system |
| US4728607A (en) * | 1984-03-22 | 1988-03-01 | J. K. And Susie L. Wadley Research Institute And Blood Bank | Miniaturized yeast identification system |
| EP0213156A1 (de) * | 1985-02-11 | 1987-03-11 | Travenol-Genentech Diagnostics | Stabilisierte enzymsubstratlösungen |
-
1990
- 1990-07-16 US US07/554,003 patent/US5098830A/en not_active Expired - Lifetime
-
1991
- 1991-07-03 EP EP91914292A patent/EP0491936B1/de not_active Expired - Lifetime
- 1991-07-03 AU AU83280/91A patent/AU655594B2/en not_active Ceased
- 1991-07-03 DE DE69114457T patent/DE69114457T2/de not_active Expired - Fee Related
- 1991-07-03 CA CA002065401A patent/CA2065401C/en not_active Expired - Fee Related
- 1991-07-03 ES ES91914292T patent/ES2078538T3/es not_active Expired - Lifetime
- 1991-07-03 WO PCT/US1991/004741 patent/WO1992001373A1/en active IP Right Grant
- 1991-07-09 ZA ZA915312A patent/ZA915312B/xx unknown
- 1991-07-15 MX MX9100216A patent/MX9100216A/es unknown
-
1992
- 1992-03-13 NO NO920993A patent/NO308545B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA915312B (en) | 1992-03-25 |
| US5098830A (en) | 1992-03-24 |
| EP0491936A4 (en) | 1992-08-26 |
| CA2065401C (en) | 2003-06-10 |
| ES2078538T3 (es) | 1995-12-16 |
| EP0491936A1 (de) | 1992-07-01 |
| AU655594B2 (en) | 1995-01-05 |
| NO920993D0 (no) | 1992-03-13 |
| CA2065401A1 (en) | 1992-01-17 |
| DE69114457D1 (de) | 1995-12-14 |
| EP0491936B1 (de) | 1995-11-08 |
| DE69114457T2 (de) | 1996-03-21 |
| MX9100216A (es) | 1992-02-28 |
| WO1992001373A1 (en) | 1992-02-06 |
| NO920993L (no) | 1992-05-15 |
| AU8328091A (en) | 1992-02-18 |
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