NO305559B1 - Substituerte bifenyl-sulfonamid-endotelin-antagonister - Google Patents

Substituerte bifenyl-sulfonamid-endotelin-antagonister

Info

Publication number
NO305559B1
NO305559B1 NO960473A NO960473A NO305559B1 NO 305559 B1 NO305559 B1 NO 305559B1 NO 960473 A NO960473 A NO 960473A NO 960473 A NO960473 A NO 960473A NO 305559 B1 NO305559 B1 NO 305559B1
Authority
NO
Norway
Prior art keywords
biphenylsulfonamide
substituted
endothelin antagonists
endothelin
antagonists
Prior art date
Application number
NO960473A
Other languages
English (en)
Norwegian (no)
Other versions
NO960473D0 (no
NO960473L (no
Inventor
Natesan Murugesan
Joel C Barrish
Philip D Stein
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/384,066 external-priority patent/US5760038A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO960473D0 publication Critical patent/NO960473D0/no
Publication of NO960473L publication Critical patent/NO960473L/no
Publication of NO305559B1 publication Critical patent/NO305559B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO960473A 1995-02-06 1996-02-05 Substituerte bifenyl-sulfonamid-endotelin-antagonister NO305559B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/384,066 US5760038A (en) 1995-02-06 1995-02-06 Substituted biphenyl sulfonamide endothelin antagonists
SG1996000999A SG46218A1 (en) 1995-02-06 1996-02-06 Substituted biphenyl sulfonamide endothelin antagonists

Publications (3)

Publication Number Publication Date
NO960473D0 NO960473D0 (no) 1996-02-05
NO960473L NO960473L (no) 1996-08-07
NO305559B1 true NO305559B1 (no) 1999-06-21

Family

ID=26665074

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960473A NO305559B1 (no) 1995-02-06 1996-02-05 Substituerte bifenyl-sulfonamid-endotelin-antagonister

Country Status (11)

Country Link
EP (1) EP0725067A1 (zh)
JP (1) JPH08245600A (zh)
CN (1) CN1060172C (zh)
CA (1) CA2168154A1 (zh)
CZ (1) CZ29296A3 (zh)
FI (1) FI960516A (zh)
HU (1) HUP9600256A3 (zh)
IL (1) IL116916A (zh)
NO (1) NO305559B1 (zh)
PL (1) PL183283B1 (zh)
SG (1) SG46218A1 (zh)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962490A (en) 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US6342610B2 (en) 1993-05-20 2002-01-29 Texas Biotechnology Corp. N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US6541498B2 (en) 1993-05-20 2003-04-01 Texas Biotechnology Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6376523B1 (en) 1994-05-20 2002-04-23 Texas Biotechnology Corporation Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6613804B2 (en) 1993-05-20 2003-09-02 Encysive Pharmaceuticals, Inc. Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US6030991A (en) * 1993-05-20 2000-02-29 Texas Biotechnology Corp. Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US5612359A (en) * 1994-08-26 1997-03-18 Bristol-Myers Squibb Company Substituted biphenyl isoxazole sulfonamides
ATE243203T1 (de) * 1995-04-04 2003-07-15 Texas Biotechnology Corp Thienyl-, furyl-, pyrrolyl- und biphenylsulfonamide und derivate zur modulation der endothelin-aktivität
US5846990A (en) * 1995-07-24 1998-12-08 Bristol-Myers Squibb Co. Substituted biphenyl isoxazole sulfonamides
JPH09124620A (ja) * 1995-10-11 1997-05-13 Bristol Myers Squibb Co 置換ビフェニルスルホンアミドエンドセリン拮抗剤
US5856507A (en) * 1997-01-21 1999-01-05 Bristol-Myers Squibb Co. Methods for the preparation of biphenyl isoxazole sulfonamides
CN1211183A (zh) * 1996-02-20 1999-03-17 布里斯托尔-迈尔斯斯奎布公司 联苯基异噁唑磺酰胺的制备方法
US5939446A (en) * 1996-04-09 1999-08-17 Bristol-Myers Squibb Co. Heteroaryl substituted phenyl isoxazole sulfonamide endothelin antagonists
US5804585A (en) * 1996-04-15 1998-09-08 Texas Biotechnology Corporation Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin
AU6187898A (en) * 1997-01-30 1998-08-25 Bristol-Myers Squibb Company Method for preventing or treating low renin hypertension by administering an endothelin antagonist
TW536540B (en) * 1997-01-30 2003-06-11 Bristol Myers Squibb Co Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe
US6030975A (en) * 1997-03-14 2000-02-29 Basf Aktiengesellschaft Carboxylic acid derivatives, their preparation and use in treating cancer
ES2241133T3 (es) 1997-04-28 2005-10-16 Encysive Pharmaceuticals Inc. Sulfamidas para el tratamiento de los trastornos inducidos por la endotelina.
US5783705A (en) 1997-04-28 1998-07-21 Texas Biotechnology Corporation Process of preparing alkali metal salys of hydrophobic sulfonamides
CA2326427A1 (en) * 1998-03-31 1999-10-07 Koichiro Yamada Preventives/remedies for urinary disorder
GEP20033114B (en) * 1998-07-06 2003-11-25 Bristol Myers Squibb Co Biphenyl Sulfonamides as Dual Angiotensin Endothelin Receptor Antagonists, Method for Their Production and Pharmaceutical Compositions Containing the Same
EP1165472A4 (en) 1999-03-19 2002-11-20 Bristol Myers Squibb Co METHOD FOR PRODUCING BIPHENYL ISOXAZOLE
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
US6639082B2 (en) 2000-10-17 2003-10-28 Bristol-Myers Squibb Company Methods for the preparation of biphenyl isoxazole sulfonamides
JP6139272B2 (ja) * 2012-06-01 2017-05-31 株式会社半導体エネルギー研究所 発光素子の作製方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ247440A (en) * 1992-05-06 1995-04-27 Squibb & Sons Inc Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
PL183283B1 (pl) 2002-06-28
CZ29296A3 (en) 1996-09-11
CN1138581A (zh) 1996-12-25
IL116916A0 (en) 1996-05-14
JPH08245600A (ja) 1996-09-24
NO960473D0 (no) 1996-02-05
IL116916A (en) 2000-09-28
PL312650A1 (en) 1996-08-19
SG46218A1 (en) 1998-02-20
HUP9600256A3 (en) 1998-08-28
EP0725067A1 (en) 1996-08-07
FI960516A0 (fi) 1996-02-05
HUP9600256A2 (en) 1997-10-28
HU9600256D0 (en) 1996-03-28
CN1060172C (zh) 2001-01-03
FI960516A (fi) 1996-08-07
NO960473L (no) 1996-08-07
CA2168154A1 (en) 1996-08-07

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Legal Events

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Free format text: LAPSED IN AUGUST 2002