NO2399993T3 - - Google Patents

Info

Publication number
NO2399993T3
NO2399993T3 NO10743584A NO10743584A NO2399993T3 NO 2399993 T3 NO2399993 T3 NO 2399993T3 NO 10743584 A NO10743584 A NO 10743584A NO 10743584 A NO10743584 A NO 10743584A NO 2399993 T3 NO2399993 T3 NO 2399993T3
Authority
NO
Norway
Application number
NO10743584A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO2399993T3 publication Critical patent/NO2399993T3/no

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6891Pre-targeting systems involving an antibody for targeting specific cells
    • A61K47/6897Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies
    • A61K47/6898Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies using avidin- or biotin-conjugated antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/14Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
NO10743584A 2009-02-20 2010-02-19 NO2399993T3 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009037750 2009-02-20
PCT/JP2010/001100 WO2010095455A1 (ja) 2009-02-20 2010-02-19 低免疫原性ストレプトアビジンおよびその利用

Publications (1)

Publication Number Publication Date
NO2399993T3 true NO2399993T3 (no) 2018-02-17

Family

ID=42633742

Family Applications (1)

Application Number Title Priority Date Filing Date
NO10743584A NO2399993T3 (no) 2009-02-20 2010-02-19

Country Status (7)

Country Link
US (1) US8546537B2 (no)
EP (1) EP2399993B1 (no)
JP (1) JP5472754B2 (no)
CN (1) CN102325884B (no)
CA (1) CA2753048C (no)
NO (1) NO2399993T3 (no)
WO (1) WO2010095455A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10065996B2 (en) * 2012-11-16 2018-09-04 Iba Gmbh Streptavidin muteins and methods of using them
JP6178586B2 (ja) 2013-02-20 2017-08-09 サヴィッド・セラピューティックス株式会社 ビオチン改変体、ストレプトアビジン変異体およびそれらの利用
EP3842440A3 (en) 2014-02-18 2021-07-07 Savid Therapeutics Inc. Modified biotin, streptavidin mutant, and usage of them
CN108291214A (zh) * 2015-09-23 2018-07-17 欧洲分子生物学实验室 抗蛋白酶的链霉亲和素
CN109983024A (zh) 2016-11-25 2019-07-05 赛威德医疗公司 清除剂
CN112243441A (zh) 2018-05-30 2021-01-19 国立大学法人东京大学 经卤化的生物素修饰二聚体及其应用
JPWO2021210573A1 (no) 2020-04-14 2021-10-21
CA3196969A1 (en) 2020-10-30 2022-05-05 Tod SPEER Oligonucleotide-based therapeutics and uses thereof
JPWO2023008515A1 (no) 2021-07-29 2023-02-02

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4135543A1 (de) 1991-10-28 1993-04-29 Boehringer Mannheim Gmbh Rekombinantes core-streptavidin
US5608060A (en) 1992-06-09 1997-03-04 Neorx Corporation Biotinidase-resistant biotin-DOTA conjugates
CA2222035A1 (en) 1995-04-11 1997-03-27 Trustees Of Boston University Streptavidin mutants
AU724942B2 (en) * 1997-02-10 2000-10-05 Her Majesty The Queen In Right Of Canada As Represented By The Department Of Agriculture And Agri-Food Canada Transgenic potatoes having reduced levels of alpha glucan L- or H-type tuber phosphorylase activity with reduced cold-sweetening
AU5597500A (en) * 1999-06-07 2000-12-28 Neorx Corporation Streptavidin expressed gene fusions and methods of use thereof
US20030143233A1 (en) 1999-06-07 2003-07-31 Neorx Corporation Streptavidin expressed gene fusions and methods of use thereof
US7148051B2 (en) * 2004-08-16 2006-12-12 E. I. Du Pont De Nemours And Company Production of 3-hydroxycarboxylic acid using nitrilase
JP5117765B2 (ja) 2007-05-28 2013-01-16 国立大学法人 東京大学 抗robo1抗体を含むpet用腫瘍診断剤

Also Published As

Publication number Publication date
WO2010095455A1 (ja) 2010-08-26
EP2399993A4 (en) 2013-07-03
CA2753048A1 (en) 2010-08-26
EP2399993B1 (en) 2017-09-20
US20120039879A1 (en) 2012-02-16
JP5472754B2 (ja) 2014-04-16
JPWO2010095455A1 (ja) 2012-08-23
CN102325884A (zh) 2012-01-18
EP2399993A1 (en) 2011-12-28
EP2399993A9 (en) 2012-07-18
CA2753048C (en) 2015-11-03
US8546537B2 (en) 2013-10-01
CN102325884B (zh) 2013-11-20

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