NO20090703L - Fremgangsmate for fremstilling av amorfe eller krystallinske former av kandesartan cilexetil ved hjelp av kolonnekromatografi - Google Patents

Fremgangsmate for fremstilling av amorfe eller krystallinske former av kandesartan cilexetil ved hjelp av kolonnekromatografi

Info

Publication number
NO20090703L
NO20090703L NO20090703A NO20090703A NO20090703L NO 20090703 L NO20090703 L NO 20090703L NO 20090703 A NO20090703 A NO 20090703A NO 20090703 A NO20090703 A NO 20090703A NO 20090703 L NO20090703 L NO 20090703L
Authority
NO
Norway
Prior art keywords
amorphous
preparation
column chromatography
crystalline forms
candesartan cilexetil
Prior art date
Application number
NO20090703A
Other languages
English (en)
Inventor
Silvo Zupancic
Anica Pecavar
Primoz Benkic
Tadej Stropnik
Joze Pucelj
Igor Plaper
Miran Hvalec
Matej Smrkolj
Renata Osolnik
Polona Smrkolj
Suzana Senicar
Nives Sostaric-Virc
Jernej Hvala
Original Assignee
Krka Tovarna Zdravil Dd Novo M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SI200600176A external-priority patent/SI22340A/sl
Priority claimed from SI200700068A external-priority patent/SI22491A/sl
Application filed by Krka Tovarna Zdravil Dd Novo M filed Critical Krka Tovarna Zdravil Dd Novo M
Publication of NO20090703L publication Critical patent/NO20090703L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Den foreliggende oppfinnelsen tilveiebringer fremgangsmåter for fremstilling av amorft og krystallinsk kandesartancileksetil med en kvalitet som er overensstemmende med Ph. Eur./ICH-retningslinjer på en økonomisk måte ved å bruke lett tilgjengelige stoffer og rene utgangsforbindelser.
NO20090703A 2006-07-28 2009-02-13 Fremgangsmate for fremstilling av amorfe eller krystallinske former av kandesartan cilexetil ved hjelp av kolonnekromatografi NO20090703L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SI200600176A SI22340A (sl) 2006-07-28 2006-07-28 Postopki za pripravo amorfnih in kristalnih oblikkandesartan cileksetila
SI200700068A SI22491A (sl) 2007-03-20 2007-03-20 Postopeki za pripravo amorfnih in kristalnih oblik kandesartan cileksetila
SI200700126 2007-05-30
PCT/EP2007/057803 WO2008012371A1 (en) 2006-07-28 2007-07-27 Process for the preparation of amorphous and crystalline forms of candesartan cilexetil using column chromatography

Publications (1)

Publication Number Publication Date
NO20090703L true NO20090703L (no) 2009-04-20

Family

ID=38529684

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090703A NO20090703L (no) 2006-07-28 2009-02-13 Fremgangsmate for fremstilling av amorfe eller krystallinske former av kandesartan cilexetil ved hjelp av kolonnekromatografi

Country Status (4)

Country Link
EP (2) EP2049510A1 (no)
EA (1) EA200900068A1 (no)
NO (1) NO20090703L (no)
WO (2) WO2008012371A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1713795A2 (en) 2004-02-11 2006-10-25 Teva Pharmaceutical Industries Ltd. Candesartan cilexetil polymorphs
ES2364011B1 (es) 2009-11-20 2013-01-24 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
JP5850697B2 (ja) * 2011-10-18 2016-02-03 株式会社トクヤマ カンデサルタンシレキセチルの製造方法
CN106770851B (zh) * 2016-12-21 2019-05-03 广东省农业科学院农业生物基因研究中心 一种液相色谱法测定类胡萝卜素的流动相配方及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems
DE69517832T2 (de) * 1994-01-28 2000-11-09 Takeda Chemical Industries, Ltd. Ein Verfahren zur Herstellung von Tetrazolyl-Verbindungen
US20040248941A1 (en) * 2001-09-25 2004-12-09 Keiji Kamiyama Benzimidazone compound, process for producing the same, and use thereof
JP4554926B2 (ja) * 2001-11-16 2010-09-29 富山化学工業株式会社 新規なベンゾフェノン誘導体またはその塩
AU2003278422A1 (en) * 2002-10-31 2004-05-25 Ranbaxy Laboratories Limited Amorphous form of losartan potassium
IL154370A0 (en) * 2003-02-10 2003-09-17 Chemagis Ltd Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same
WO2005037821A2 (en) * 2003-10-16 2005-04-28 Teva Pharmaceutical Industries Ltd. Preparation of candesartan cilexetil
EP1713795A2 (en) * 2004-02-11 2006-10-25 Teva Pharmaceutical Industries Ltd. Candesartan cilexetil polymorphs
US20050250827A1 (en) * 2004-05-05 2005-11-10 Etinger Marina Y Preparation of candesartan cilexetil in high purity
WO2005123720A1 (en) * 2004-06-18 2005-12-29 Ranbaxy Laboratories Limited Fine particles of the angiotensin ii antagonist candesartan cilexetil and process for production thereof
CA2611293A1 (en) * 2005-06-06 2007-07-05 Medichem, S.A. Process for the preparation of tetrazolyl compounds

Also Published As

Publication number Publication date
WO2008012372A1 (en) 2008-01-31
WO2008012371A1 (en) 2008-01-31
EP2049510A1 (en) 2009-04-22
EA200900068A1 (ru) 2009-06-30
EP2066649A1 (en) 2009-06-10

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application