NO20090265L - Oral farmasoytisk sammensetning av en enkel vannloselig aktiv substans - Google Patents

Oral farmasoytisk sammensetning av en enkel vannloselig aktiv substans

Info

Publication number
NO20090265L
NO20090265L NO20090265A NO20090265A NO20090265L NO 20090265 L NO20090265 L NO 20090265L NO 20090265 A NO20090265 A NO 20090265A NO 20090265 A NO20090265 A NO 20090265A NO 20090265 L NO20090265 L NO 20090265L
Authority
NO
Norway
Prior art keywords
oral pharmaceutical
soluble active
pharmaceutical composition
active substance
weight
Prior art date
Application number
NO20090265A
Other languages
English (en)
Inventor
Amarjit Singh
Rajesh Jain
Munish Talwar
Henricus R M Gorissen
Kour C Jindal
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Publication of NO20090265L publication Critical patent/NO20090265L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Det beskrives forbedrede, orale farmasøytiske preparater omfattende minst et lite vannoppløselig, aktivt middel, fortrinnsvis endotelinkonverteringsenzym (ECE) inhibitor og/eller nøytral endopeptidase (NEP) inhibitor i en mengde mer enn 10 vekt-% av preparatet. Hvis det benyttes et alkalisystem omfattende en blanding av minst to alkaliske forbindelser i vektforholdet 1:20 til 20:1, er det aktive middel SLV-306 eller farmasøytisk akseptable salter, estere, hydrater, solvater, isomerer eller derivater derav. Det alkaliske system benyttes fortrinnsvis i en mengde større enn 10 vekt-% av preparatet og omfatter fortrinnsvis en blanding av minst to alkaliske forbindelser og eventuelt en eller flere farmasøytisk akseptable eksipienter. Det tilveiebringes videre en fremgangsmåte for fremstilling av slike forbedrede preparater samt en fremgangsmåte for å anvende slike preparater.
NO20090265A 2006-06-22 2009-01-16 Oral farmasoytisk sammensetning av en enkel vannloselig aktiv substans NO20090265L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81557906P 2006-06-22 2006-06-22
IN1473DE2006 2006-06-22
EP06115881 2006-06-22
PCT/EP2007/056207 WO2007147873A1 (en) 2006-06-22 2007-06-21 Oral pharmaceutical composition of a poorly water-soluble active substance

Publications (1)

Publication Number Publication Date
NO20090265L true NO20090265L (no) 2009-01-22

Family

ID=38475974

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090265A NO20090265L (no) 2006-06-22 2009-01-16 Oral farmasoytisk sammensetning av en enkel vannloselig aktiv substans

Country Status (9)

Country Link
EP (1) EP2037890A1 (no)
JP (1) JP2009541267A (no)
KR (1) KR20090033246A (no)
AU (1) AU2007263016A1 (no)
CA (1) CA2654243A1 (no)
EA (1) EA200970045A1 (no)
IL (1) IL195653A0 (no)
NO (1) NO20090265L (no)
WO (1) WO2007147873A1 (no)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1397160A1 (en) * 2001-04-30 2004-03-17 Shire Laboratories Inc. Pharmaceutical composition including ace/nep inhibitors and bioavailability enhancers
AR038681A1 (es) * 2002-02-14 2005-01-26 Solvay Pharm Bv Formulacion oral de solucion solida de una sustancia activa pobremente soluble en agua
WO2004062692A1 (en) * 2003-01-13 2004-07-29 Solvay Pharmaceuticals B.V. Formulation of poorly water-soluble active substances
TW200633713A (en) * 2004-12-23 2006-10-01 Solvay Pharm Bv Oral immediate release formulation of a poorly water-soluble active substance
WO2007054975A1 (en) * 2005-11-08 2007-05-18 Panacea Biotec Ltd Pharmaceutical compositions for the treatment of cardiovascular and other associated disorders

Also Published As

Publication number Publication date
EP2037890A1 (en) 2009-03-25
WO2007147873A1 (en) 2007-12-27
KR20090033246A (ko) 2009-04-01
AU2007263016A1 (en) 2007-12-27
EA200970045A1 (ru) 2009-06-30
JP2009541267A (ja) 2009-11-26
CA2654243A1 (en) 2007-12-27
IL195653A0 (en) 2009-09-01

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application