NO20083301L - Karbohydrat-mimetiske peptider samt anvendelse derav i farmasoytiske sammensetninger - Google Patents
Karbohydrat-mimetiske peptider samt anvendelse derav i farmasoytiske sammensetningerInfo
- Publication number
- NO20083301L NO20083301L NO20083301A NO20083301A NO20083301L NO 20083301 L NO20083301 L NO 20083301L NO 20083301 A NO20083301 A NO 20083301A NO 20083301 A NO20083301 A NO 20083301A NO 20083301 L NO20083301 L NO 20083301L
- Authority
- NO
- Norway
- Prior art keywords
- bacterial
- formulations
- serogroup
- bound
- repeating units
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 150000001720 carbohydrates Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 3
- 229960005486 vaccine Drugs 0.000 abstract 3
- 241000588650 Neisseria meningitidis Species 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000004676 glycans Polymers 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 150000004804 polysaccharides Polymers 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Foreliggende oppfinnelse angår farmasøytisk industri og bioteknologi, særlig vaksineantigener anvendt ovenfor bakterielle, virale, kreft eller annen opprinnelsesykdommer. Utvikling av farmasøytiske formuleringer i stand til å beskytte eller å øke det beskyttende spekteret til allerede utviklede vaksiner og å utvikle dem ovenfor flere patogener, ved å bruke som mål for immunresponsen, karbohydrater bestående av repeterende enheter av (a 2-8) bundet N-erstattet neuraminsyre. Flere peptider ble isolert og identifisert som molekylære mimetiske midler til den kapsulære polisakkaridform serogruppe B til Neisseria meningitidis, som består av repeterende enheter av (a 2-8) bundet N-asetyl neuraminsyre. Immunogenisiteten til peptider ble evaluert i dyre modeller, som demonstrerer deres verdi som antigener i stand til å indusere produksjon av antistoffer i stand til spesifikt å gjenkjenne bakterie N. meningitidis fra serogruppe B og å vise bakteriell aktivitet ovenfor samme. De resulterende formuleringene av disse er anvendbare innen farmasøytisk industri som vaksineformuleringer for human anvendelse.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20050283 | 2005-12-29 | ||
| PCT/CU2006/000020 WO2007073706A2 (es) | 2005-12-29 | 2006-12-28 | Péptidos miméticos de carbohidratos y su empleo en formulaciones farmacéuticas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20083301L true NO20083301L (no) | 2008-09-26 |
Family
ID=37946113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20083301A NO20083301L (no) | 2005-12-29 | 2008-07-28 | Karbohydrat-mimetiske peptider samt anvendelse derav i farmasoytiske sammensetninger |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1982994A2 (no) |
| KR (1) | KR20080090477A (no) |
| CN (1) | CN101389643A (no) |
| AR (1) | AR058736A1 (no) |
| AU (1) | AU2006331226A1 (no) |
| BR (1) | BRPI0620937A2 (no) |
| CA (1) | CA2634067A1 (no) |
| MX (1) | MX2008008582A (no) |
| NO (1) | NO20083301L (no) |
| WO (1) | WO2007073706A2 (no) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0611914D0 (en) | 2006-06-15 | 2006-07-26 | Teti Giuseppe | Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU602483B2 (en) * | 1985-01-18 | 1990-10-18 | Immunetech Pharmaceuticals | Immunoregulatory peptides |
| CA2264585C (en) * | 1996-08-27 | 2005-06-14 | Chiron Corporation | Monoclonal antibodies that define unique meningococcal b epitopes and their use in the preparation of vaccine compositions |
| AU9120898A (en) * | 1997-08-27 | 1999-03-16 | Chiron Corporation | Molecular mimetics of meningococcal b epitopes |
| GB0024200D0 (en) * | 2000-10-03 | 2000-11-15 | Smithkline Beecham Sa | Component vaccine |
-
2006
- 2006-12-26 AR ARP060105778A patent/AR058736A1/es unknown
- 2006-12-28 CA CA002634067A patent/CA2634067A1/en not_active Abandoned
- 2006-12-28 AU AU2006331226A patent/AU2006331226A1/en not_active Abandoned
- 2006-12-28 MX MX2008008582A patent/MX2008008582A/es unknown
- 2006-12-28 BR BRPI0620937-8A patent/BRPI0620937A2/pt not_active Application Discontinuation
- 2006-12-28 EP EP06828471A patent/EP1982994A2/en not_active Withdrawn
- 2006-12-28 KR KR1020087018521A patent/KR20080090477A/ko not_active Application Discontinuation
- 2006-12-28 CN CNA2006800534515A patent/CN101389643A/zh active Pending
- 2006-12-28 WO PCT/CU2006/000020 patent/WO2007073706A2/es active Application Filing
-
2008
- 2008-07-28 NO NO20083301A patent/NO20083301L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1982994A2 (en) | 2008-10-22 |
| AR058736A1 (es) | 2008-02-20 |
| CA2634067A1 (en) | 2007-07-05 |
| WO2007073706A3 (es) | 2007-09-13 |
| MX2008008582A (es) | 2008-09-26 |
| WO2007073706A2 (es) | 2007-07-05 |
| AU2006331226A1 (en) | 2007-07-05 |
| BRPI0620937A2 (pt) | 2011-11-29 |
| KR20080090477A (ko) | 2008-10-08 |
| CN101389643A (zh) | 2009-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |