NO20082288L - Monoklonalt anti-ADDL-antistoff og anvendelse derav - Google Patents
Monoklonalt anti-ADDL-antistoff og anvendelse deravInfo
- Publication number
- NO20082288L NO20082288L NO20082288A NO20082288A NO20082288L NO 20082288 L NO20082288 L NO 20082288L NO 20082288 A NO20082288 A NO 20082288A NO 20082288 A NO20082288 A NO 20082288A NO 20082288 L NO20082288 L NO 20082288L
- Authority
- NO
- Norway
- Prior art keywords
- addl
- types
- antibodies
- disease
- monoclonal anti
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2005381125 | 2005-10-21 | ||
PCT/US2006/040508 WO2007050359A2 (fr) | 2005-10-21 | 2006-10-17 | Anticorps monoclonal anti-addl et leur utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082288L true NO20082288L (no) | 2008-05-19 |
Family
ID=39671607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082288A NO20082288L (no) | 2005-10-21 | 2008-05-19 | Monoklonalt anti-ADDL-antistoff og anvendelse derav |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1940466B1 (fr) |
JP (1) | JP5289963B2 (fr) |
CN (1) | CN101291692A (fr) |
AU (1) | AU2006306553B9 (fr) |
CA (1) | CA2626783A1 (fr) |
NO (1) | NO20082288L (fr) |
RU (1) | RU2008120027A (fr) |
WO (1) | WO2007050359A2 (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001268005A1 (en) | 2000-07-07 | 2002-01-21 | Lars Lannfelt | Prevention and treatment of alzheimer's disease |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
SE0401601D0 (sv) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
DK1976877T4 (en) | 2005-11-30 | 2017-01-16 | Abbvie Inc | Monoclonal antibodies to amyloid beta protein and uses thereof |
KR20080090408A (ko) | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
CN101421303B (zh) | 2006-03-23 | 2013-06-12 | 生命北极神经科学公司 | 改进的初原纤维选择性抗体及其用途 |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
US20100311767A1 (en) | 2007-02-27 | 2010-12-09 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
US8323654B2 (en) | 2007-05-14 | 2012-12-04 | Medtronic, Inc. | Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules |
US7931899B2 (en) | 2007-05-14 | 2011-04-26 | Medtronic, Inc | Humanized anti-amyloid beta antibodies |
KR20150055103A (ko) * | 2007-06-12 | 2015-05-20 | 에이씨 이뮨 에스.에이. | 아밀로이드 베타에 대해 인간화된 항체 |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
US9403902B2 (en) | 2007-10-05 | 2016-08-02 | Ac Immune S.A. | Methods of treating ocular disease associated with amyloid-beta-related pathology using an anti-amyloid-beta antibody |
WO2009070648A2 (fr) * | 2007-11-27 | 2009-06-04 | Medtronic, Inc. | Anticorps anti-amyloïde bêta humanisés |
US9217024B2 (en) | 2007-12-18 | 2015-12-22 | Acumen Pharmaceuticals, Inc. | ADDL receptor polypeptides, polynucleotides and host cells for recombinant production |
US20110144311A1 (en) * | 2008-08-14 | 2011-06-16 | Rebecca Chmielowski | Methods for purifying antibodies using protein a affinity chromatography |
DK2510359T3 (en) | 2009-12-11 | 2015-12-07 | Araclón Biotech S L | METHODS AND REAGENTS FOR IMPROVED DETECTION OF AMYLOID-BETA PEPTIDES |
JP2013523182A (ja) | 2010-04-15 | 2013-06-17 | アボット・ラボラトリーズ | アミロイドベータ結合タンパク質 |
US9176151B2 (en) | 2010-07-14 | 2015-11-03 | Acumen Pharmaceuticals, Inc. | Antibodies, kit and method for detecting amyloid beta oligomers |
MX338640B (es) * | 2010-07-14 | 2016-04-25 | Merck Sharp & Dohme | Anticuerpo monoclonal anti-ligando difundible derivado de amiloide beta y usos de los mismos. |
US9320793B2 (en) | 2010-07-14 | 2016-04-26 | Acumen Pharmaceuticals, Inc. | Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42 |
JP6081356B2 (ja) | 2010-07-30 | 2017-02-15 | エーシー イミューン エス.エー. | 安全で機能的なヒト化抗βアミロイド抗体 |
CN105348387B (zh) | 2010-08-14 | 2020-08-25 | Abbvie 公司 | β淀粉样蛋白结合蛋白 |
US20140302532A1 (en) | 2011-04-12 | 2014-10-09 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury |
EP2511296A1 (fr) | 2011-04-12 | 2012-10-17 | Araclón Biotech, S. L. | Anticorps, kit et procédé pour déterminer des peptides amyloïdes |
JP2014521089A (ja) * | 2011-07-13 | 2014-08-25 | メルク・シャープ・アンド・ドーム・コーポレーション | 液体試料中のアミロイドベータオリゴマーの検出方法およびその使用 |
SI3166970T1 (sl) | 2014-07-10 | 2021-09-30 | Bioarctic Ab | Izboljšana A-beta protofibril vezavna protitelesa |
WO2018156180A1 (fr) * | 2017-02-24 | 2018-08-30 | Kindred Biosciences, Inc. | Anticorps anti-il31 à usage vétérinaire |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE239797T1 (de) * | 1993-01-25 | 2003-05-15 | Takeda Chemical Industries Ltd | Antikörper gegen beta-amyloid oder derivative davon und seine verwendung |
US5786180A (en) * | 1995-02-14 | 1998-07-28 | Bayer Corporation | Monoclonal antibody 369.2B specific for β A4 peptide |
US20030068316A1 (en) * | 1997-02-05 | 2003-04-10 | Klein William L. | Anti-ADDL antibodies and uses thereof |
JP3816111B2 (ja) * | 1997-04-09 | 2006-08-30 | インテレクト・ニューロサイエンシズ・インコーポレーテッド | β−アミロイド末端に特異的な組換え抗体、それをコードするDNA及びその使用法 |
JP2006508072A (ja) * | 2002-10-01 | 2006-03-09 | ノースウエスタン ユニバーシティ | アミロイドベータ由来拡散性リガンド(ADDLs)、ADDL代替物、ADDL結合性分子、およびそれらの使用 |
PE20050627A1 (es) * | 2003-05-30 | 2005-08-10 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
AU2005306997B2 (en) * | 2004-10-25 | 2012-07-05 | Merck Sharp & Dohme Corp. | Anti-ADDL antibodies and uses thereof |
-
2006
- 2006-10-17 CA CA002626783A patent/CA2626783A1/fr not_active Abandoned
- 2006-10-17 RU RU2008120027/13A patent/RU2008120027A/ru not_active Application Discontinuation
- 2006-10-17 AU AU2006306553A patent/AU2006306553B9/en not_active Expired - Fee Related
- 2006-10-17 EP EP06836346A patent/EP1940466B1/fr active Active
- 2006-10-17 JP JP2008536730A patent/JP5289963B2/ja active Active
- 2006-10-17 WO PCT/US2006/040508 patent/WO2007050359A2/fr active Application Filing
- 2006-10-17 CN CNA2006800392637A patent/CN101291692A/zh active Pending
-
2008
- 2008-05-19 NO NO20082288A patent/NO20082288L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2007050359A2 (fr) | 2007-05-03 |
AU2006306553B2 (en) | 2011-08-25 |
EP1940466A2 (fr) | 2008-07-09 |
EP1940466B1 (fr) | 2012-11-28 |
CN101291692A (zh) | 2008-10-22 |
AU2006306553A1 (en) | 2007-05-03 |
CA2626783A1 (fr) | 2007-05-03 |
RU2008120027A (ru) | 2009-11-27 |
JP2009519895A (ja) | 2009-05-21 |
WO2007050359A8 (fr) | 2008-05-08 |
WO2007050359A3 (fr) | 2007-06-21 |
EP1940466A4 (fr) | 2010-04-07 |
AU2006306553B9 (en) | 2011-09-29 |
JP5289963B2 (ja) | 2013-09-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20082288L (no) | Monoklonalt anti-ADDL-antistoff og anvendelse derav | |
NO20072700L (no) | Anti-ADDL antistoffer og anvendelser derav | |
MX2022005782A (es) | Anticuerpos monoclonales contra la proteina amiloide beta y usos de los mismos. | |
MX2009012950A (es) | ANTICUERPOS HUMANIZADOS CONTRA EL GLOBULOMERO Aß (20-42) Y SUS USOS. | |
MX2009012949A (es) | Anticuerpos humanizados que enlazan a ab (1-42) globulomero y usos de los mismos. | |
LUC00053I9 (fr) | Anticorps diriges contre cd38 pour le traitement du myelome multiple | |
WO2012045882A3 (fr) | Composition pharmaceutique | |
WO2010115843A3 (fr) | Composition pharmaceutique | |
MA45655A (fr) | Anticorps spécifiques de la protéine tau hyperphosphorylée et leurs procédés d'utilisation | |
MX354662B (es) | Anticuerpos fosfoespecificos que reconocen la tau. | |
MX338640B (es) | Anticuerpo monoclonal anti-ligando difundible derivado de amiloide beta y usos de los mismos. | |
WO2005018424A3 (fr) | Anticorps specifiques de la proteine amyloide fibrillaire et procedure permettant de detecter des depots de proteines amyloides fibrillaires | |
TR201800669T4 (tr) | Alzheimer hastaliğinda tau-aracili patoloji̇ni̇n tanilanmasi ve protei̇n bazli tedavi̇si̇ | |
WO2006099698A3 (fr) | Nouvel anticorps anti-plgf | |
WO2007062245A3 (fr) | Anticorps monoclonal humain cd134 (ox40) et procedes de fabrication et d'utilisation de celui-ci | |
AR083819A1 (es) | UN ANTICUERPO QUE SE UNE A BACE1 (ENZIMA 1 DE DISOCIACION DE PROTEINA PRECURSORA DEL AMILOIDE DE SITIO b), METODOS Y COMPOSICIONES PARA INMUNOTERAPIA PARA ENFERMEDAD NEURAL | |
NZ596409A (en) | Anti macrophage migration inhibitory factor antibodies | |
EA200901436A1 (ru) | Антигенсвязывающие белки, связывающие par-2 | |
EA200801343A1 (ru) | Иммуноглобулины, направленные против nogo | |
CR20210492A (es) | ANTICUERPOS CONTRA AMILOIDES-ß CON PIROGLUTAMATO Y USOS DE ESTOS | |
EA201290671A1 (ru) | Антигенсвязывающие белки, специфические в отношении сывороточного амилоидного компонента р | |
WO2008051326A3 (fr) | Identification de contactines et de cams l1 en tant que ligands pour la protéine précurseur amyloïde | |
WO2017027685A3 (fr) | Molécules à base d'anticorps spécifiques de l'épitope asp421 tronqué de la protéine tau et leurs utilisations dans le diagnostic et le traitement de tauopathie | |
WO2014159244A3 (fr) | Anticorps tau d'o-glcnac et son utilisation | |
EA200702634A1 (ru) | Гуманизированные антитела, специфичные в отношении nogo-a, и их фармацевтические применения |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |