NO20073239L - TNF-antagonister - Google Patents
TNF-antagonisterInfo
- Publication number
- NO20073239L NO20073239L NO20073239A NO20073239A NO20073239L NO 20073239 L NO20073239 L NO 20073239L NO 20073239 A NO20073239 A NO 20073239A NO 20073239 A NO20073239 A NO 20073239A NO 20073239 L NO20073239 L NO 20073239L
- Authority
- NO
- Norway
- Prior art keywords
- tnf
- polypeptides
- treatment
- binding
- tnf antagonists
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4726—Lectins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Rheumatology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Sammendrag TNF-bindende polypeptider basert på humane tetranektin C-type lectinliknende domener (TTLD) med forbedret bindingsegenskaper og forbedret effektivitet. Polypeptidene omfatter et TNF-bindende domene med aminosyresekvensen KRWSRYF (SEQ ID NO: l). Det frembringes også fremgangsmåte for å fremstille polypetiden ifølge oppfinnelsen. Polypeptidene kan anvendes for fremstilling av farmasøytiske sammensetninger, og for behandling av et individ som har en patologi mediert TNF, slik som behandling av reumatoid artritt.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62934304P | 2004-11-22 | 2004-11-22 | |
DKPA200401813 | 2004-11-22 | ||
PCT/DK2005/000742 WO2006053568A1 (en) | 2004-11-22 | 2005-11-21 | Tnf antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20073239L true NO20073239L (no) | 2007-08-17 |
Family
ID=35840156
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20073239A NO20073239L (no) | 2004-11-22 | 2007-06-22 | TNF-antagonister |
Country Status (10)
Country | Link |
---|---|
US (1) | US7820622B2 (no) |
EP (1) | EP1824878A1 (no) |
JP (1) | JP2008520214A (no) |
KR (1) | KR20070095296A (no) |
AU (1) | AU2005306168A1 (no) |
BR (1) | BRPI0518042A (no) |
CA (1) | CA2587948A1 (no) |
NO (1) | NO20073239L (no) |
NZ (1) | NZ555353A (no) |
WO (1) | WO2006053568A1 (no) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ568809A (en) | 2005-12-22 | 2011-08-26 | Genentech Inc | Recovering and purification of VEGF proteins from prokaryotic cells using polyanionic agents |
ZA200900229B (en) | 2006-07-14 | 2010-04-28 | Genentech Inc | Refolding of recombinant proteins |
BRPI0719597A2 (pt) | 2006-11-22 | 2013-12-17 | Adnexus A Bristol Myers Squibb R & D Company | Produtos terapêuticos objetivados baseados em proteínas manipuladas para receptores de quinases de tirosina, incluindo igf-ir |
EP2072527A1 (en) | 2007-12-21 | 2009-06-24 | Altonabiotec AG | Fusion polypeptides comprising a SHBG dimerization component and uses thereof |
JP2011520961A (ja) | 2008-05-22 | 2011-07-21 | ブリストル−マイヤーズ スクイブ カンパニー | 多価フィブロネクチンをベースとする足場ドメインタンパク質 |
WO2010042890A2 (en) * | 2008-10-10 | 2010-04-15 | Anaphore, Inc. | Polypeptides that bind trail-ri and trail-r2 |
US20110086806A1 (en) * | 2009-10-09 | 2011-04-14 | Anaphore, Inc. | Polypeptides that Bind IL-23R |
CN107969128A (zh) | 2015-04-17 | 2018-04-27 | 高山免疫科学股份有限公司 | 具有可调的亲和力的免疫调节蛋白 |
US11124558B2 (en) * | 2017-06-02 | 2021-09-21 | The Feinstein Institutes For Medical Research | Use of tetranectin and peptide agonists to treat inflammatory diseases |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9409768D0 (en) | 1994-05-16 | 1994-07-06 | Medical Res Council | Trimerising polypeptides |
ATE282092T1 (de) | 1997-06-11 | 2004-11-15 | Borean Pharma As | Trimerisierendes modul |
WO2002048189A2 (en) | 2000-12-13 | 2002-06-20 | Borean Pharma A/S | Combinatorial libraries of proteins having the scaffold structure of c-type lectin-like domains |
AU2003225416A1 (en) | 2002-06-25 | 2004-01-06 | Medical Patents Limited | Injection syringe having a retractable injection needle |
CA2503697A1 (en) | 2002-10-29 | 2004-05-13 | Borean Pharma A/S | Trimeric binding proteins for trimeric cytokines |
-
2005
- 2005-11-21 JP JP2007541691A patent/JP2008520214A/ja active Pending
- 2005-11-21 AU AU2005306168A patent/AU2005306168A1/en not_active Abandoned
- 2005-11-21 WO PCT/DK2005/000742 patent/WO2006053568A1/en active Application Filing
- 2005-11-21 US US11/719,942 patent/US7820622B2/en not_active Expired - Fee Related
- 2005-11-21 KR KR1020077013927A patent/KR20070095296A/ko not_active Application Discontinuation
- 2005-11-21 BR BRPI0518042-2A patent/BRPI0518042A/pt not_active Application Discontinuation
- 2005-11-21 EP EP05803991A patent/EP1824878A1/en not_active Withdrawn
- 2005-11-21 CA CA002587948A patent/CA2587948A1/en not_active Abandoned
- 2005-11-21 NZ NZ555353A patent/NZ555353A/en not_active IP Right Cessation
-
2007
- 2007-06-22 NO NO20073239A patent/NO20073239L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BRPI0518042A (pt) | 2008-10-28 |
WO2006053568A1 (en) | 2006-05-26 |
KR20070095296A (ko) | 2007-09-28 |
NZ555353A (en) | 2009-12-24 |
JP2008520214A (ja) | 2008-06-19 |
EP1824878A1 (en) | 2007-08-29 |
US7820622B2 (en) | 2010-10-26 |
US20090155843A1 (en) | 2009-06-18 |
CA2587948A1 (en) | 2006-05-26 |
AU2005306168A1 (en) | 2006-05-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CREP | Change of representative |
Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA, 0125 OSLO, NO |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |