NO20072445L - Krystallinske former av 3-[5-klor-4-[(2,4-difluorbenzyl)oksy]-6-oksypyrimidin-1 (6H)-yl]-N-(2-hydroksyetyl)-4-metylbenzamid - Google Patents

Krystallinske former av 3-[5-klor-4-[(2,4-difluorbenzyl)oksy]-6-oksypyrimidin-1 (6H)-yl]-N-(2-hydroksyetyl)-4-metylbenzamid

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Publication number
NO20072445L
NO20072445L NO20072445A NO20072445A NO20072445L NO 20072445 L NO20072445 L NO 20072445L NO 20072445 A NO20072445 A NO 20072445A NO 20072445 A NO20072445 A NO 20072445A NO 20072445 L NO20072445 L NO 20072445L
Authority
NO
Norway
Prior art keywords
crystalline forms
difluorobenzyl
methylbenzamide
oxy
hydroxyethyl
Prior art date
Application number
NO20072445A
Other languages
English (en)
Norwegian (no)
Inventor
Jon Gordon Selbo
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of NO20072445L publication Critical patent/NO20072445L/no

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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
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NO20072445A 2004-10-13 2007-05-11 Krystallinske former av 3-[5-klor-4-[(2,4-difluorbenzyl)oksy]-6-oksypyrimidin-1 (6H)-yl]-N-(2-hydroksyetyl)-4-metylbenzamid NO20072445L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61846604P 2004-10-13 2004-10-13
PCT/IB2005/003030 WO2006040649A1 (fr) 2004-10-13 2005-10-03 Formes cristallines de 3-[5-chloro-4-[(2,4-difluorobenzyl) oxy]-6-oxopyrimidin-1(6h)-yl]-n-(2-hydroxyethyl)-4-methylbenzamide

Publications (1)

Publication Number Publication Date
NO20072445L true NO20072445L (no) 2007-07-09

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NO20072445A NO20072445L (no) 2004-10-13 2007-05-11 Krystallinske former av 3-[5-klor-4-[(2,4-difluorbenzyl)oksy]-6-oksypyrimidin-1 (6H)-yl]-N-(2-hydroksyetyl)-4-metylbenzamid

Country Status (16)

Country Link
US (2) US8324230B2 (fr)
EP (2) EP1802589B1 (fr)
JP (1) JP4937129B2 (fr)
KR (1) KR100872675B1 (fr)
CN (1) CN101039921A (fr)
AR (1) AR051384A1 (fr)
AU (1) AU2005293290A1 (fr)
BR (1) BRPI0516001A (fr)
CA (1) CA2584246C (fr)
ES (1) ES2463681T3 (fr)
IL (1) IL181815A0 (fr)
MX (1) MX2007004514A (fr)
NO (1) NO20072445L (fr)
TW (1) TWI303633B (fr)
WO (1) WO2006040649A1 (fr)
ZA (1) ZA200701999B (fr)

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FR2849029B1 (fr) 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
EP1992344A1 (fr) 2007-05-18 2008-11-19 Institut Curie P38 alpha comme cible therapeutique pour les maladies associées á une mutation de FGFR3
PE20120003A1 (es) * 2009-01-30 2012-02-12 Glaxosmithkline Llc Hidrocloruro de n-{(1s)-2-amino-1-[(3-fluorofenil)metil)etil}-5-cloro-4-(4-cloro-1-metil-1h-pirazol-5-il)-2-tiofenocarboxamida cristalino
HUE029371T2 (en) 2009-11-27 2017-02-28 Genzyme Corp GENZ 112638 For treatment of Gaucher or Fabry disease in combination therapy
SG10201600077RA (en) 2011-01-11 2016-02-26 Glaxosmithkline Llc Combination
KR101252711B1 (ko) * 2011-03-31 2013-04-09 김두철 가구용 경첩
MX2015000830A (es) 2012-07-18 2015-10-26 Sunshine Lake Pharma Co Ltd Derivados heterociclicos nitrogenosos y su aplicacion en farmacos.
ES2663806T3 (es) 2013-12-19 2018-04-17 unshine Lake Pharma Co., Ltd. Derivados heterocíclicos nitrogenados y su aplicación en el tratamiento de la fibrosis tisular

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JPS61205261A (ja) 1985-03-08 1986-09-11 Sagami Chem Res Center ６―置換―５―フルオロウラシル誘導体
AU7798994A (en) 1993-10-20 1995-05-08 Upjohn Company, The Pyrimidinones as antiarthritic and anti-inflammatories
AU735901C (en) 1996-12-05 2004-02-12 Amgen, Inc. Substituted pyrimidinone and pyridone compounds and methods of use
JP2002517486A (ja) * 1998-06-12 2002-06-18 バーテックス ファーマシューティカルズ インコーポレイテッド ｐ３８のインヒビター
WO2001029010A1 (fr) * 1999-10-21 2001-04-26 Merck & Co., Inc. Composes antibacteriens a selectivite gram-positif, compositions contenant ces composes et methodes therapeutiques
EP1553949B1 (fr) 2002-08-13 2007-04-18 Warner-Lambert Company LLC Derives de pyrimidine 2,4-diones, utilises comme inhibiteurs de metalloproteinase matricielle
US7183287B2 (en) * 2003-04-03 2007-02-27 Pharmacia Corporation Substituted pyrimidinones
US20070167621A1 (en) 2003-04-03 2007-07-19 Pharmacia Corporation Substituted pyrimidinones

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KR20070083663A (ko) 2007-08-24
KR100872675B1 (ko) 2008-12-10
US20080269264A1 (en) 2008-10-30
EP1802589B1 (fr) 2014-04-09
CA2584246C (fr) 2011-08-09
EP1802589A1 (fr) 2007-07-04
JP2008515963A (ja) 2008-05-15
MX2007004514A (es) 2007-05-09
IL181815A0 (en) 2007-07-04
AR051384A1 (es) 2007-01-10
TWI303633B (en) 2008-12-01
TW200626562A (en) 2006-08-01
US8324230B2 (en) 2012-12-04
CA2584246A1 (fr) 2006-04-20
ES2463681T3 (es) 2014-05-28
US8933088B2 (en) 2015-01-13
ZA200701999B (en) 2008-10-29
AU2005293290A1 (en) 2006-04-20
EP2708531A1 (fr) 2014-03-19
US20130158053A1 (en) 2013-06-20
BRPI0516001A (pt) 2008-08-19
JP4937129B2 (ja) 2012-05-23
CN101039921A (zh) 2007-09-19

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