NO20071936L - Polymorphs of the cysteine protease inhibitor N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl-2 (R) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) propionamide - Google Patents

Polymorphs of the cysteine protease inhibitor N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl-2 (R) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) propionamide

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Publication number
NO20071936L
NO20071936L NO20071936A NO20071936A NO20071936L NO 20071936 L NO20071936 L NO 20071936L NO 20071936 A NO20071936 A NO 20071936A NO 20071936 A NO20071936 A NO 20071936A NO 20071936 L NO20071936 L NO 20071936L
Authority
NO
Norway
Prior art keywords
polymorphs
cyanocyclopropyl
propionamide
trifluoro
cyclopropylmethanesulfonyl
Prior art date
Application number
NO20071936A
Other languages
Norwegian (no)
Inventor
Sheila M Zipfel
Soon H Woo
Donglai Yang
Simon Bates
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/943,768 external-priority patent/US7547701B2/en
Priority claimed from PCT/US2005/033074 external-priority patent/WO2006034006A1/en
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of NO20071936L publication Critical patent/NO20071936L/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Foreliggende oppfinnelse er rettet mot polymorfer av N-(1-cyansyklopropyl)-3-syklopropylmetansulfonyl2(R)-(2,2,2-trifluor-l(S)-4-fluorfenyletylamino)propionamid, metoder for anvendelse av disse for å behandle en sykdom formidlet av cathepsin S, farmasøytiske preparater omfattende slike polymorfer, og fremgangsmåter for fremstilling av disse.The present invention is directed to polymorphs of N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl2 (R) - (2,2,2-trifluoro-1 (S) -4-fluorophenylethylamino) propionamide, methods of using them to treat a disease mediated by cathepsin S, pharmaceutical compositions comprising such polymorphs, and methods for their preparation.

NO20071936A 2004-09-17 2007-04-16 Polymorphs of the cysteine protease inhibitor N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl-2 (R) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) propionamide NO20071936L (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/943,768 US7547701B2 (en) 2003-09-18 2004-09-17 Haloalkyl containing compounds as cysteine protease inhibitors
PCT/US2004/030442 WO2005028429A2 (en) 2003-09-18 2004-09-17 Haloalkyl containing compounds as cysteine protease inhibitors
US66424405P 2005-03-21 2005-03-21
PCT/US2005/033074 WO2006034006A1 (en) 2004-09-17 2005-09-16 Polymorphs of the cysteine protease inhibitor n- (1-cyanocyclopropyl)-3-cyclopropylmethansulfonyl-2 (r) - (2,2,2-trifluoro-1 (s) - (4-fluorophenyl) ethylamino) propionamide

Publications (1)

Publication Number Publication Date
NO20071936L true NO20071936L (en) 2007-06-12

Family

ID=38325575

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071936A NO20071936L (en) 2004-09-17 2007-04-16 Polymorphs of the cysteine protease inhibitor N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl-2 (R) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) propionamide

Country Status (5)

Country Link
BR (1) BRPI0515449A2 (en)
IL (1) IL181791A0 (en)
MX (1) MX2007003112A (en)
NO (1) NO20071936L (en)
ZA (1) ZA200703104B (en)

Also Published As

Publication number Publication date
BRPI0515449A2 (en) 2008-12-16
IL181791A0 (en) 2007-07-04
ZA200703104B (en) 2008-09-25
MX2007003112A (en) 2007-05-21

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