NO20071936L - Polymorphs of the cysteine protease inhibitor N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl-2 (R) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) propionamide - Google Patents
Polymorphs of the cysteine protease inhibitor N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl-2 (R) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) propionamideInfo
- Publication number
- NO20071936L NO20071936L NO20071936A NO20071936A NO20071936L NO 20071936 L NO20071936 L NO 20071936L NO 20071936 A NO20071936 A NO 20071936A NO 20071936 A NO20071936 A NO 20071936A NO 20071936 L NO20071936 L NO 20071936L
- Authority
- NO
- Norway
- Prior art keywords
- polymorphs
- cyanocyclopropyl
- propionamide
- trifluoro
- cyclopropylmethanesulfonyl
- Prior art date
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Foreliggende oppfinnelse er rettet mot polymorfer av N-(1-cyansyklopropyl)-3-syklopropylmetansulfonyl2(R)-(2,2,2-trifluor-l(S)-4-fluorfenyletylamino)propionamid, metoder for anvendelse av disse for å behandle en sykdom formidlet av cathepsin S, farmasøytiske preparater omfattende slike polymorfer, og fremgangsmåter for fremstilling av disse.The present invention is directed to polymorphs of N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl2 (R) - (2,2,2-trifluoro-1 (S) -4-fluorophenylethylamino) propionamide, methods of using them to treat a disease mediated by cathepsin S, pharmaceutical compositions comprising such polymorphs, and methods for their preparation.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/943,768 US7547701B2 (en) | 2003-09-18 | 2004-09-17 | Haloalkyl containing compounds as cysteine protease inhibitors |
PCT/US2004/030442 WO2005028429A2 (en) | 2003-09-18 | 2004-09-17 | Haloalkyl containing compounds as cysteine protease inhibitors |
US66424405P | 2005-03-21 | 2005-03-21 | |
PCT/US2005/033074 WO2006034006A1 (en) | 2004-09-17 | 2005-09-16 | Polymorphs of the cysteine protease inhibitor n- (1-cyanocyclopropyl)-3-cyclopropylmethansulfonyl-2 (r) - (2,2,2-trifluoro-1 (s) - (4-fluorophenyl) ethylamino) propionamide |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20071936L true NO20071936L (en) | 2007-06-12 |
Family
ID=38325575
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20071936A NO20071936L (en) | 2004-09-17 | 2007-04-16 | Polymorphs of the cysteine protease inhibitor N- (1-cyanocyclopropyl) -3-cyclopropylmethanesulfonyl-2 (R) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) propionamide |
Country Status (5)
Country | Link |
---|---|
BR (1) | BRPI0515449A2 (en) |
IL (1) | IL181791A0 (en) |
MX (1) | MX2007003112A (en) |
NO (1) | NO20071936L (en) |
ZA (1) | ZA200703104B (en) |
-
2005
- 2005-09-16 MX MX2007003112A patent/MX2007003112A/en unknown
- 2005-09-16 BR BRPI0515449-9A patent/BRPI0515449A2/en not_active Application Discontinuation
-
2007
- 2007-03-08 IL IL181791A patent/IL181791A0/en unknown
- 2007-04-16 NO NO20071936A patent/NO20071936L/en unknown
- 2007-04-16 ZA ZA200703104A patent/ZA200703104B/en unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0515449A2 (en) | 2008-12-16 |
IL181791A0 (en) | 2007-07-04 |
ZA200703104B (en) | 2008-09-25 |
MX2007003112A (en) | 2007-05-21 |
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