MX2007003112A - Polymorphs of the cysteine protease inhibitor n- (1-cyanocyclopropyl)-3-cyclopropylmethansulfonyl-2 (r) - (2,2,2-trifluoro-1 (s) - (4-fluorophenyl) ethylamino) propionamide. - Google Patents

Polymorphs of the cysteine protease inhibitor n- (1-cyanocyclopropyl)-3-cyclopropylmethansulfonyl-2 (r) - (2,2,2-trifluoro-1 (s) - (4-fluorophenyl) ethylamino) propionamide.

Info

Publication number
MX2007003112A
MX2007003112A MX2007003112A MX2007003112A MX2007003112A MX 2007003112 A MX2007003112 A MX 2007003112A MX 2007003112 A MX2007003112 A MX 2007003112A MX 2007003112 A MX2007003112 A MX 2007003112A MX 2007003112 A MX2007003112 A MX 2007003112A
Authority
MX
Mexico
Prior art keywords
polymorphs
cyanocyclopropyl
propionamide
trifluoro
cyclopropylmethansulfonyl
Prior art date
Application number
MX2007003112A
Other languages
Spanish (es)
Inventor
Simon Bates
Sheila M Zipfel
Soon H Woo
Donglai Yang
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/943,768 external-priority patent/US7547701B2/en
Application filed by Schering Ag filed Critical Schering Ag
Priority claimed from PCT/US2005/033074 external-priority patent/WO2006034006A1/en
Publication of MX2007003112A publication Critical patent/MX2007003112A/en

Links

Abstract

The present invention is directed to polymorphs of N-(1-cyanocyclopropyl)-3-cyclopropylmethanesulfonyl-2(R)-(2,2,2 -trifluoro-1(S)-4-fluorophenylethylamino)-propionamide, methods of using them to treat a disease mediated by cathepsin S, pharmaceutical compositions comprising such polymorphs, and processes for preparing them.
MX2007003112A 2004-09-17 2005-09-16 Polymorphs of the cysteine protease inhibitor n- (1-cyanocyclopropyl)-3-cyclopropylmethansulfonyl-2 (r) - (2,2,2-trifluoro-1 (s) - (4-fluorophenyl) ethylamino) propionamide. MX2007003112A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/943,768 US7547701B2 (en) 2003-09-18 2004-09-17 Haloalkyl containing compounds as cysteine protease inhibitors
PCT/US2004/030442 WO2005028429A2 (en) 2003-09-18 2004-09-17 Haloalkyl containing compounds as cysteine protease inhibitors
US66424405P 2005-03-21 2005-03-21
PCT/US2005/033074 WO2006034006A1 (en) 2004-09-17 2005-09-16 Polymorphs of the cysteine protease inhibitor n- (1-cyanocyclopropyl)-3-cyclopropylmethansulfonyl-2 (r) - (2,2,2-trifluoro-1 (s) - (4-fluorophenyl) ethylamino) propionamide

Publications (1)

Publication Number Publication Date
MX2007003112A true MX2007003112A (en) 2007-05-21

Family

ID=38325575

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007003112A MX2007003112A (en) 2004-09-17 2005-09-16 Polymorphs of the cysteine protease inhibitor n- (1-cyanocyclopropyl)-3-cyclopropylmethansulfonyl-2 (r) - (2,2,2-trifluoro-1 (s) - (4-fluorophenyl) ethylamino) propionamide.

Country Status (5)

Country Link
BR (1) BRPI0515449A2 (en)
IL (1) IL181791A0 (en)
MX (1) MX2007003112A (en)
NO (1) NO20071936L (en)
ZA (1) ZA200703104B (en)

Also Published As

Publication number Publication date
BRPI0515449A2 (en) 2008-12-16
IL181791A0 (en) 2007-07-04
ZA200703104B (en) 2008-09-25
NO20071936L (en) 2007-06-12

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