NO20063456L - Azadecalin glukokortikoid reseptor modulatorer - Google Patents

Azadecalin glukokortikoid reseptor modulatorer

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Publication number
NO20063456L
NO20063456L NO20063456A NO20063456A NO20063456L NO 20063456 L NO20063456 L NO 20063456L NO 20063456 A NO20063456 A NO 20063456A NO 20063456 A NO20063456 A NO 20063456A NO 20063456 L NO20063456 L NO 20063456L
Authority
NO
Norway
Prior art keywords
receptor modulators
glucocorticoid receptor
azadecaline
compounds
methods
Prior art date
Application number
NO20063456A
Other languages
English (en)
Inventor
Robin Douglas Clark
Paul Blaney
Nicholas C Ray
Christopher Hurley
Karen Williams
Hazel Hunt
David Clark
Original Assignee
Corcept Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corcept Therapeutics Inc filed Critical Corcept Therapeutics Inc
Publication of NO20063456L publication Critical patent/NO20063456L/no

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    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
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    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
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Abstract

Foreliggende oppfinnelse tilveiebringer en ny klasse av azadecalinforbindelser og fremgangsmåter for , anvendelse av forbindelsene som glukokortikoidreseptormodulatorer.
NO20063456A 2004-01-09 2006-07-26 Azadecalin glukokortikoid reseptor modulatorer NO20063456L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53546004P 2004-01-09 2004-01-09
PCT/US2005/000607 WO2005070893A2 (en) 2004-01-09 2005-01-10 Azadecalin glucocorticoid receptor modulators

Publications (1)

Publication Number Publication Date
NO20063456L true NO20063456L (no) 2006-09-26

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NO20063456A NO20063456L (no) 2004-01-09 2006-07-26 Azadecalin glukokortikoid reseptor modulatorer

Country Status (19)

Country Link
US (2) US7678813B2 (no)
EP (1) EP1761497B1 (no)
JP (1) JP4851345B2 (no)
KR (1) KR101135885B1 (no)
CN (1) CN101119970A (no)
AT (1) ATE407122T1 (no)
AU (1) AU2005206497B2 (no)
CA (1) CA2552419C (no)
CY (1) CY1110491T1 (no)
DE (1) DE602005009530D1 (no)
DK (1) DK1761497T3 (no)
ES (1) ES2313296T3 (no)
HK (1) HK1097409A1 (no)
IL (1) IL176706A (no)
NO (1) NO20063456L (no)
NZ (1) NZ548374A (no)
PT (1) PT1761497E (no)
WO (1) WO2005070893A2 (no)
ZA (1) ZA200605634B (no)

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TW200820977A (en) 2006-08-08 2008-05-16 Organon Nv Use of glucocorticoid receptor antagonists for treatment of infectious conditions
EP2008600B1 (en) * 2007-06-25 2010-09-22 Terumo Kabushiki Kaisha Medical device
EP2211845B1 (en) * 2007-10-17 2017-02-22 Laboratoire HRA Pharma Glucocorticoid receptor antagonists such as mifepristone for treating cushing's syndrome
AU2009267016B2 (en) * 2008-07-01 2014-07-03 Corcept Therapeutics, Inc. Use of mifepristone for the treatment of Amyotrophic Lateral Sclerosis
SG187909A1 (en) * 2010-08-27 2013-03-28 Corcept Therapeutics Inc Pyridyl-amine fused azadecalin modulators
EP2661175A4 (en) 2011-01-07 2013-12-04 Corcept Therapeutics Inc COMBINATION STEROID AND GLUCOCORTICOID RECEPTORANT AGONIST THERAPY
WO2012129074A1 (en) * 2011-03-18 2012-09-27 Corcept Therapeutics, Inc. Pyrimidine cyclohexyl glucocorticoid receptor modulators
US8859774B2 (en) 2012-05-25 2014-10-14 Corcept Therapeutics, Inc. Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
AU2014352915B2 (en) 2013-11-25 2018-03-15 Corcept Therapeutics, Inc. Octahydro fused azadecalin glucocorticoid receptor modulators
US9829495B2 (en) 2015-08-13 2017-11-28 Corcept Therapeutics, Inc. Method for differentially diagnosing ACTH-dependent Cushing's syndrome
JP6765443B2 (ja) 2016-01-19 2020-10-07 コーセプト セラピューティクス, インコーポレイテッド 異所性クッシング症候群の鑑別診断
KR102342620B1 (ko) 2017-03-31 2021-12-22 코어셉트 쎄라퓨틱스 인코포레이티드 자궁경부암을 치료하기 위한 글루코코르티코이드 수용체 조정제
WO2020132046A1 (en) 2018-12-19 2020-06-25 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
US11234971B2 (en) 2018-12-19 2022-02-01 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
CN113194931B (zh) 2018-12-19 2023-11-10 科塞普特治疗公司 含有瑞拉可兰、杂芳基-酮稠合的氮杂十氢化萘化合物的药物制剂
JP2022523376A (ja) 2019-02-22 2022-04-22 コーセプト セラピューティクス, インコーポレイテッド レラコリラント、ヘテロアリール-ケトン縮合アザデカリングルココルチコイド受容体調節物質の治療用途
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CN115361952A (zh) * 2020-01-29 2022-11-18 科赛普特治疗学股份有限公司 用选择性糖皮质激素受体调节剂(sgrm)和抗体检查点抑制剂治疗肾上腺皮质癌
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WO2005070893A2 (en) 2005-08-04
ES2313296T3 (es) 2009-03-01
IL176706A0 (en) 2006-10-31
PT1761497E (pt) 2008-09-25
US20100120759A1 (en) 2010-05-13
IL176706A (en) 2012-06-28
DE602005009530D1 (de) 2008-10-16
JP4851345B2 (ja) 2012-01-11
CA2552419A1 (en) 2005-08-04
US20070203179A1 (en) 2007-08-30
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EP1761497B1 (en) 2008-09-03
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