NO20062664L - Fremgangsmate for fremstilling av 4-pentafluorid-sulfanyl-benzoylguanidiner - Google Patents

Fremgangsmate for fremstilling av 4-pentafluorid-sulfanyl-benzoylguanidiner

Info

Publication number
NO20062664L
NO20062664L NO20062664A NO20062664A NO20062664L NO 20062664 L NO20062664 L NO 20062664L NO 20062664 A NO20062664 A NO 20062664A NO 20062664 A NO20062664 A NO 20062664A NO 20062664 L NO20062664 L NO 20062664L
Authority
NO
Norway
Prior art keywords
benzoylguanidines
pentafluoride
sulfanyl
preparation
formula
Prior art date
Application number
NO20062664A
Other languages
English (en)
Inventor
Gerrit Schubert
Heinz-Werner Kleemann
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of NO20062664L publication Critical patent/NO20062664L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Det er beskrevet en fremgangsmåte for fremstilling av 4-pentafluoridsulfanylbenzoylguanidiner med formel I, hvor R1 til R4 har betydningen angitt i kravene. Forbindelsene med formel I er NHE1-inhibitorer og kan eksempelvis anvendes for behandling av hjertekretsløpsykdommer.
NO20062664A 2003-11-13 2006-06-09 Fremgangsmate for fremstilling av 4-pentafluorid-sulfanyl-benzoylguanidiner NO20062664L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10353204A DE10353204A1 (de) 2003-11-13 2003-11-13 Verfahren zur Herstellung von 4-Pentafluorsulfanyl-benzoylguanidinen
PCT/EP2004/012395 WO2005047241A1 (de) 2003-11-13 2004-11-03 Verfahren zur herstellung von 4-pentafluorsulfanyl-benzoylguanidinen

Publications (1)

Publication Number Publication Date
NO20062664L true NO20062664L (no) 2006-08-10

Family

ID=34585095

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062664A NO20062664L (no) 2003-11-13 2006-06-09 Fremgangsmate for fremstilling av 4-pentafluorid-sulfanyl-benzoylguanidiner

Country Status (23)

Country Link
EP (1) EP1685097B1 (no)
JP (1) JP4658955B2 (no)
KR (1) KR101207223B1 (no)
CN (2) CN100480237C (no)
AR (1) AR046374A1 (no)
AT (1) ATE386019T1 (no)
AU (1) AU2004288760B2 (no)
BR (1) BRPI0416570A (no)
CA (1) CA2545291C (no)
CY (1) CY1107922T1 (no)
DE (2) DE10353204A1 (no)
DK (1) DK1685097T3 (no)
ES (1) ES2298838T3 (no)
HK (2) HK1095582A1 (no)
IL (1) IL175238A (no)
NO (1) NO20062664L (no)
NZ (1) NZ547170A (no)
PL (1) PL1685097T3 (no)
PT (1) PT1685097E (no)
RU (1) RU2382030C2 (no)
TW (1) TWI334859B (no)
WO (1) WO2005047241A1 (no)
ZA (1) ZA200602575B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7317124B2 (en) * 2003-11-13 2008-01-08 Sanofi-Aventis Deutschland Gmbh Ortho-substituted pentafluorosulfanylbenzenes, process for their preparation and their use as valuable synthetic intermediates
EP2321274A1 (en) * 2008-07-08 2011-05-18 Boehringer Ingelheim International GmbH Pyrrolidinyl and piperidinyl compounds useful as nhe-1 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3721268A1 (de) * 1987-06-27 1989-01-12 Merck Patent Gmbh Arylschwefelpentafluoride
ES2097409T3 (es) * 1992-09-22 1997-04-01 Hoechst Ag Benzoilguanidinas, procedimiento para su preparacion, asi como su empleo como antiarritmicos.
GB9306183D0 (en) * 1993-03-25 1993-05-19 Zeneca Ltd Novel compounds
DE4417004A1 (de) * 1994-05-13 1995-11-16 Hoechst Ag Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
GB9606015D0 (en) * 1996-03-22 1996-05-22 Rhone Poulenc Agriculture New herbicides
DE10222192A1 (de) * 2002-05-18 2003-11-27 Aventis Pharma Gmbh Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
CN100480237C (zh) 2009-04-22
AU2004288760A1 (en) 2005-05-26
WO2005047241A1 (de) 2005-05-26
CA2545291A1 (en) 2005-05-26
HK1095582A1 (en) 2007-05-11
PT1685097E (pt) 2008-04-10
DE10353204A1 (de) 2005-06-16
CN101475519A (zh) 2009-07-08
CA2545291C (en) 2012-10-30
KR101207223B1 (ko) 2012-12-03
ZA200602575B (en) 2007-05-30
EP1685097B1 (de) 2008-02-13
TWI334859B (en) 2010-12-21
DE502004006216D1 (de) 2008-03-27
HK1133870A1 (en) 2010-04-09
RU2006120473A (ru) 2007-12-27
CN1878754A (zh) 2006-12-13
DK1685097T3 (da) 2008-06-09
ES2298838T3 (es) 2008-05-16
RU2382030C2 (ru) 2010-02-20
IL175238A (en) 2011-06-30
JP4658955B2 (ja) 2011-03-23
AU2004288760B2 (en) 2011-04-07
EP1685097A1 (de) 2006-08-02
TW200530161A (en) 2005-09-16
CN101475519B (zh) 2012-04-25
KR20060122849A (ko) 2006-11-30
AR046374A1 (es) 2005-12-07
ATE386019T1 (de) 2008-03-15
NZ547170A (en) 2009-12-24
IL175238A0 (en) 2006-09-05
BRPI0416570A (pt) 2007-01-23
CY1107922T1 (el) 2013-09-04
JP2007510685A (ja) 2007-04-26
PL1685097T3 (pl) 2008-06-30

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