NO20055601L - Pharmaceutical preparation in the form of a hydrogel for transdermal administration of active ingredients - Google Patents

Pharmaceutical preparation in the form of a hydrogel for transdermal administration of active ingredients

Info

Publication number
NO20055601L
NO20055601L NO20055601A NO20055601A NO20055601L NO 20055601 L NO20055601 L NO 20055601L NO 20055601 A NO20055601 A NO 20055601A NO 20055601 A NO20055601 A NO 20055601A NO 20055601 L NO20055601 L NO 20055601L
Authority
NO
Norway
Prior art keywords
hydrogel
active ingredients
pharmaceutical preparation
transdermal administration
active ingredient
Prior art date
Application number
NO20055601A
Other languages
Norwegian (no)
Other versions
NO20055601D0 (en
Inventor
Patrick Franke
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33395772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20055601(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20055601D0 publication Critical patent/NO20055601D0/en
Publication of NO20055601L publication Critical patent/NO20055601L/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Abstract

Farmasøytisk preparat i form av en hydrogel omfattende karboksylsyreester, C-C-alkylalkohol, virkestoff og polymermatriks. Det beskrives også anvendelse av en karboksylsyreester som transdermalt permeeringsmiddel for et virkestoff i et farmasøytisk preparat i form av en hydrogel, hvor preparatet omfatter en polymermatriks Og C-C-alkylalkohol. Videre beskrives et svettebestandig preparat i form av en hydrogel omfattende en akrylsyre kombinert med et cellulosederivat.Pharmaceutical composition in the form of a hydrogel comprising carboxylic acid ester, C 1 -C 4 alkyl alcohol, active ingredient and polymer matrix. It is also described the use of a carboxylic acid ester as a transdermal permeating agent for an active ingredient in a pharmaceutical composition in the form of a hydrogel, the composition comprising a polymer matrix and C 1 -C 4 alkyl alcohol. Furthermore, a sweat-resistant preparation in the form of a hydrogel comprising an acrylic acid combined with a cellulose derivative is described.

NO20055601A 2003-04-28 2005-11-25 Pharmaceutical preparation in the form of a hydrogel for transdermal administration of active ingredients NO20055601L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03008856 2003-04-28
PCT/EP2004/004224 WO2004096191A1 (en) 2003-04-28 2004-04-21 Pharmaceutical composition in the form of a hydrogel for transdermal administration of active substances

Publications (2)

Publication Number Publication Date
NO20055601D0 NO20055601D0 (en) 2005-11-25
NO20055601L true NO20055601L (en) 2006-01-26

Family

ID=33395772

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055601A NO20055601L (en) 2003-04-28 2005-11-25 Pharmaceutical preparation in the form of a hydrogel for transdermal administration of active ingredients

Country Status (33)

Country Link
EP (2) EP1617827B1 (en)
JP (2) JP4829102B2 (en)
KR (1) KR101093999B1 (en)
CN (1) CN1780610B (en)
AR (1) AR044113A1 (en)
AT (2) ATE467412T1 (en)
AU (1) AU2004233572B2 (en)
BR (1) BRPI0409918A (en)
CA (1) CA2523734C (en)
CL (1) CL2004000884A1 (en)
CO (1) CO5640075A2 (en)
CR (1) CR8059A (en)
CY (1) CY1108069T1 (en)
DE (2) DE502004006196D1 (en)
DK (1) DK1617827T3 (en)
EA (1) EA008686B1 (en)
EC (1) ECSP056186A (en)
ES (2) ES2300763T3 (en)
HK (1) HK1087633A1 (en)
HR (1) HRP20080178T3 (en)
JO (1) JO2492B1 (en)
MX (1) MXPA05011541A (en)
NO (1) NO20055601L (en)
NZ (2) NZ543264A (en)
PE (1) PE20050461A1 (en)
PL (1) PL1617827T3 (en)
PT (1) PT1617827E (en)
RS (1) RS51307B (en)
SI (1) SI1617827T1 (en)
TW (1) TWI343259B (en)
UA (1) UA83036C2 (en)
WO (1) WO2004096191A1 (en)
ZA (1) ZA200509549B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0506139D0 (en) * 2005-03-24 2005-05-04 Transphase Ltd A transdermal topical composition and its uses
GB0506141D0 (en) * 2005-03-24 2005-05-04 Transphase Ltd A topical compostion and its uses
DE102005015128B4 (en) * 2005-03-31 2008-12-11 Bayer Schering Pharma Aktiengesellschaft Wafers containing steroid hormones
DE102005035879A1 (en) * 2005-07-30 2007-02-01 Paul Hartmann Ag Hydrogel useful as a wound filler or dressing comprises a gel-forming polysaccharide, an acrylic acid derivative and an electrolyte mixture
SE536091C2 (en) * 2011-04-14 2013-04-30 Pep Tonic Medical Ab Pharmaceutical composition containing oxytocin or fragments or variants thereof and at least one non-ionic cellulose ether
PL2702982T3 (en) * 2011-04-25 2017-07-31 Jun-Hyoung Park Composition for topical application for preventing hair loss and stimulating hair growth
FR2976808B1 (en) * 2011-06-22 2013-06-28 Urgo Lab FILMOGENE COMPOSITION AND USE THEREOF FOR THE TREATMENT OF HERPES
US9855211B2 (en) * 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
DE102018213754A1 (en) * 2018-08-15 2020-02-20 Henkel Ag & Co. Kgaa "Tris (hydroxymethyl-) aminomethane or its salts as an active ingredient to reduce sweat secretion"

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341557A (en) 1961-06-05 1967-09-12 Upjohn Co 7-methyltestosterones
DE1182229B (en) 1960-11-16 1964-11-26 Upjohn Co Process for the preparation of 7-methyl steroids
US3924004A (en) 1971-11-24 1975-12-02 Syntex Corp Fatty alcohol-propylene carbonate-glycol solvent cream vehicle
US4000273A (en) 1973-11-01 1976-12-28 Richardson-Merrell Inc. Method for the control of fertility
JPS5540604A (en) * 1978-09-14 1980-03-22 Mitsui Toatsu Chem Inc Improved local topicum
FR2518879A1 (en) * 1981-12-30 1983-07-01 Besins Jean Topical oestradiol compsns. - for treatment of disorders associated with menopause
JPS5970612A (en) * 1982-10-13 1984-04-21 Nippon Redarii Kk Gel ointment base
DE3868248D1 (en) * 1987-05-27 1992-03-12 Burghart Kurt TRANSDERMAL THERAPEUTICALLY ACTIVE PHARMACEUTICAL PREPARATION AND DEVICE FOR APPLYING THE PREPARATION.
HU210549B (en) * 1988-10-27 1995-05-29 Schering Ag Process for producing transdermally applicable pharmaceutical composition containing gestodene
JPH08501529A (en) * 1992-06-11 1996-02-20 セラテック・インコーポレイテッド Use of glycerin to alleviate skin-penetrating drug administration
US5460620A (en) * 1992-07-31 1995-10-24 Creative Products Resource, Inc. Method of applying in-tandem applicator pads for transdermal delivery of a therapeutic agent
AU3723695A (en) 1994-09-14 1996-03-29 Minnesota Mining And Manufacturing Company Transdermal device for delivery of levonorgestrel
FR2732223B1 (en) 1995-03-30 1997-06-13 Sanofi Sa PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL ADMINISTRATION
DE19526864A1 (en) 1995-07-22 1997-01-23 Labtec Gmbh Hormone patches
JPH09194396A (en) 1996-01-17 1997-07-29 Pola Chem Ind Inc Matrix for percutaneous patch material
US5733565A (en) 1996-02-23 1998-03-31 The Population Council, Center For Biomedical Research Male contraceptive implant
KR970064620A (en) * 1996-03-05 1997-10-13 임성기 Cyclosporin-containing external-use pharmaceutical composition
US5736128A (en) * 1996-05-14 1998-04-07 Isp Investments Inc. Cosmetic composition for rejuvenation of skin without skin irritation
CA2256365A1 (en) 1996-05-22 1997-11-27 Diversified Pharmaceuticals, Inc. Compositions, methods and devices for the transdermal delivery of drugs
IT1283102B1 (en) * 1996-06-06 1998-04-07 Permatec Nv THERAPEUTIC COMPOSITION FOR THE TRANSDERMAL ADMINISTRATION OF AN ESTROGENIC OR PROGESTINIC ACTIVE SUBSTANCE OR OF THEIR MIXTURES
US5993787A (en) 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
US6767902B2 (en) 1997-09-17 2004-07-27 The Population Council, Inc. Androgen as a male contraceptive and non-contraceptive androgen replacement
US20020012694A1 (en) 1997-09-17 2002-01-31 Alfred J. Moo-Young Transdermal administration of ment
DK1087986T3 (en) 1998-06-19 2002-06-17 Akzo Nobel Nv testosterone derivative
FR2781666B1 (en) * 1998-07-30 2000-09-08 Oreal SOLID COSMETIC COMPOSITION AND USES THEREOF
JP2935113B1 (en) * 1998-09-24 1999-08-16 小林製薬株式会社 Indomethacin transdermal absorbent
AU2003600A (en) 1999-01-13 2000-08-01 Taisho Pharmaceutical Co., Ltd. External steroid preparation
JP2000264899A (en) * 1999-01-13 2000-09-26 Taisho Pharmaceut Co Ltd External preparation of steroid
JP2001139451A (en) * 1999-11-17 2001-05-22 Lion Corp Gelatinous cosmetic
MXPA03005372A (en) 2000-12-15 2004-04-20 Akzo Nobel Nv 14(15)-unsaturated 15- and/or 16- substituted androgens with mixed androgen-progestational profile.
DE10104327A1 (en) * 2001-01-24 2002-07-25 Schering Ag New 11beta-halo-testosterone derivatives useful in male hormone replacement therapy and in male fertility control
DE10107663B4 (en) 2001-02-19 2004-09-09 Lts Lohmann Therapie-Systeme Ag Testosterone-containing transdermal therapeutic system, process for its preparation and its use

Also Published As

Publication number Publication date
PT1617827E (en) 2008-04-30
AU2004233572B2 (en) 2010-07-15
DK1617827T3 (en) 2008-06-02
CR8059A (en) 2006-05-29
CA2523734C (en) 2009-12-22
TWI343259B (en) 2011-06-11
CO5640075A2 (en) 2006-05-31
RS20050809A (en) 2007-09-21
NZ583760A (en) 2011-10-28
RS51307B (en) 2010-12-31
EP1875905B1 (en) 2010-05-12
EA008686B1 (en) 2007-06-29
CL2004000884A1 (en) 2005-03-11
CN1780610A (en) 2006-05-31
AU2004233572A1 (en) 2004-11-11
ATE467412T1 (en) 2010-05-15
BRPI0409918A (en) 2006-04-25
NO20055601D0 (en) 2005-11-25
PE20050461A1 (en) 2005-08-13
PL1617827T3 (en) 2008-07-31
EP1617827B1 (en) 2008-02-13
EP1617827A1 (en) 2006-01-25
JP2010241824A (en) 2010-10-28
CN1780610B (en) 2010-06-09
ES2300763T3 (en) 2008-06-16
CY1108069T1 (en) 2014-02-12
JP2006524653A (en) 2006-11-02
HRP20080178T3 (en) 2008-05-31
ATE385786T1 (en) 2008-03-15
WO2004096191A1 (en) 2004-11-11
NZ543264A (en) 2010-03-26
SI1617827T1 (en) 2008-06-30
CA2523734A1 (en) 2004-11-11
HK1087633A1 (en) 2006-10-20
ZA200509549B (en) 2007-02-28
AR044113A1 (en) 2005-08-24
MXPA05011541A (en) 2006-05-31
JO2492B1 (en) 2009-10-05
EA200501583A1 (en) 2006-06-30
EP1875905A2 (en) 2008-01-09
TW200524644A (en) 2005-08-01
EP1875905A3 (en) 2008-06-25
JP4829102B2 (en) 2011-12-07
KR20060007403A (en) 2006-01-24
ECSP056186A (en) 2006-04-19
ES2345458T3 (en) 2010-09-23
DE502004011164D1 (en) 2010-06-24
KR101093999B1 (en) 2011-12-15
UA83036C2 (en) 2008-06-10
DE502004006196D1 (en) 2008-03-27

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