DK1617827T3 - Pharmaceutical composition in the form of a hydrogel for the transdermal administration of active substances - Google Patents

Pharmaceutical composition in the form of a hydrogel for the transdermal administration of active substances

Info

Publication number
DK1617827T3
DK1617827T3 DK04728563T DK04728563T DK1617827T3 DK 1617827 T3 DK1617827 T3 DK 1617827T3 DK 04728563 T DK04728563 T DK 04728563T DK 04728563 T DK04728563 T DK 04728563T DK 1617827 T3 DK1617827 T3 DK 1617827T3
Authority
DK
Denmark
Prior art keywords
hydrogel
pharmaceutical composition
active substances
transdermal administration
transdermal
Prior art date
Application number
DK04728563T
Other languages
Danish (da)
Inventor
Patrick Franke
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33395772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1617827(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of DK1617827T3 publication Critical patent/DK1617827T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK04728563T 2003-04-28 2004-04-21 Pharmaceutical composition in the form of a hydrogel for the transdermal administration of active substances DK1617827T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03008856 2003-04-28
PCT/EP2004/004224 WO2004096191A1 (en) 2003-04-28 2004-04-21 Pharmaceutical composition in the form of a hydrogel for transdermal administration of active substances

Publications (1)

Publication Number Publication Date
DK1617827T3 true DK1617827T3 (en) 2008-06-02

Family

ID=33395772

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04728563T DK1617827T3 (en) 2003-04-28 2004-04-21 Pharmaceutical composition in the form of a hydrogel for the transdermal administration of active substances

Country Status (33)

Country Link
EP (2) EP1875905B1 (en)
JP (2) JP4829102B2 (en)
KR (1) KR101093999B1 (en)
CN (1) CN1780610B (en)
AR (1) AR044113A1 (en)
AT (2) ATE385786T1 (en)
AU (1) AU2004233572B2 (en)
BR (1) BRPI0409918A (en)
CA (1) CA2523734C (en)
CL (1) CL2004000884A1 (en)
CO (1) CO5640075A2 (en)
CR (1) CR8059A (en)
CY (1) CY1108069T1 (en)
DE (2) DE502004011164D1 (en)
DK (1) DK1617827T3 (en)
EA (1) EA008686B1 (en)
EC (1) ECSP056186A (en)
ES (2) ES2345458T3 (en)
HK (1) HK1087633A1 (en)
HR (1) HRP20080178T3 (en)
JO (1) JO2492B1 (en)
MX (1) MXPA05011541A (en)
NO (1) NO20055601L (en)
NZ (2) NZ543264A (en)
PE (1) PE20050461A1 (en)
PL (1) PL1617827T3 (en)
PT (1) PT1617827E (en)
RS (1) RS51307B (en)
SI (1) SI1617827T1 (en)
TW (1) TWI343259B (en)
UA (1) UA83036C2 (en)
WO (1) WO2004096191A1 (en)
ZA (1) ZA200509549B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0506141D0 (en) * 2005-03-24 2005-05-04 Transphase Ltd A topical compostion and its uses
GB0506139D0 (en) * 2005-03-24 2005-05-04 Transphase Ltd A transdermal topical composition and its uses
DE102005015128B4 (en) * 2005-03-31 2008-12-11 Bayer Schering Pharma Aktiengesellschaft Wafers containing steroid hormones
DE102005035879A1 (en) * 2005-07-30 2007-02-01 Paul Hartmann Ag Hydrogel useful as a wound filler or dressing comprises a gel-forming polysaccharide, an acrylic acid derivative and an electrolyte mixture
SE536091C2 (en) * 2011-04-14 2013-04-30 Pep Tonic Medical Ab Pharmaceutical composition containing oxytocin or fragments or variants thereof and at least one non-ionic cellulose ether
JP5934781B2 (en) * 2011-04-25 2016-06-15 パーク、ジュン−ヒョン External preparation composition for preventing hair loss and promoting hair growth
FR2976808B1 (en) * 2011-06-22 2013-06-28 Urgo Lab FILMOGENE COMPOSITION AND USE THEREOF FOR THE TREATMENT OF HERPES
US9855211B2 (en) * 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
DE102018213754A1 (en) * 2018-08-15 2020-02-20 Henkel Ag & Co. Kgaa "Tris (hydroxymethyl-) aminomethane or its salts as an active ingredient to reduce sweat secretion"

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341557A (en) 1961-06-05 1967-09-12 Upjohn Co 7-methyltestosterones
DE1182229B (en) 1960-11-16 1964-11-26 Upjohn Co Process for the preparation of 7-methyl steroids
US3924004A (en) 1971-11-24 1975-12-02 Syntex Corp Fatty alcohol-propylene carbonate-glycol solvent cream vehicle
US4000273A (en) 1973-11-01 1976-12-28 Richardson-Merrell Inc. Method for the control of fertility
JPS5540604A (en) * 1978-09-14 1980-03-22 Mitsui Toatsu Chem Inc Improved local topicum
FR2518879A1 (en) * 1981-12-30 1983-07-01 Besins Jean Topical oestradiol compsns. - for treatment of disorders associated with menopause
JPS5970612A (en) 1982-10-13 1984-04-21 Nippon Redarii Kk Gel ointment base
JPH01503281A (en) * 1987-05-27 1989-11-09 ブルグハルト，クルト Pharmaceutical dressings effective for transdermal treatment and devices for applying the same
WO1990004397A1 (en) * 1988-10-27 1990-05-03 Schering Aktiengesellschaft Berlin Und Bergkamen Preparation for transdermal application containing gestodene
JPH08501529A (en) * 1992-06-11 1996-02-20 セラテック・インコーポレイテッド Use of glycerin to alleviate skin-penetrating drug administration
US5460620A (en) * 1992-07-31 1995-10-24 Creative Products Resource, Inc. Method of applying in-tandem applicator pads for transdermal delivery of a therapeutic agent
AU3723695A (en) 1994-09-14 1996-03-29 Minnesota Mining And Manufacturing Company Transdermal device for delivery of levonorgestrel
FR2732223B1 (en) 1995-03-30 1997-06-13 Sanofi Sa PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL ADMINISTRATION
DE19526864A1 (en) 1995-07-22 1997-01-23 Labtec Gmbh Hormone patches
JPH09194396A (en) 1996-01-17 1997-07-29 Pola Chem Ind Inc Matrix for percutaneous patch material
US5733565A (en) 1996-02-23 1998-03-31 The Population Council, Center For Biomedical Research Male contraceptive implant
KR970064620A (en) * 1996-03-05 1997-10-13 임성기 Cyclosporin-containing external-use pharmaceutical composition
US5736128A (en) * 1996-05-14 1998-04-07 Isp Investments Inc. Cosmetic composition for rejuvenation of skin without skin irritation
EP0954260A1 (en) 1996-05-22 1999-11-10 Diversified Pharmaceuticals, Inc. Compositions, methods and devices for the transdermal delivery of drugs
IT1283102B1 (en) * 1996-06-06 1998-04-07 Permatec Nv THERAPEUTIC COMPOSITION FOR THE TRANSDERMAL ADMINISTRATION OF AN ESTROGENIC OR PROGESTINIC ACTIVE SUBSTANCE OR OF THEIR MIXTURES
US5993787A (en) 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
US6767902B2 (en) 1997-09-17 2004-07-27 The Population Council, Inc. Androgen as a male contraceptive and non-contraceptive androgen replacement
US20020012694A1 (en) 1997-09-17 2002-01-31 Alfred J. Moo-Young Transdermal administration of ment
ID27260A (en) 1998-06-19 2001-03-22 Akzo Nobel Nv TESTOSTERON DOWN
FR2781666B1 (en) * 1998-07-30 2000-09-08 Oreal SOLID COSMETIC COMPOSITION AND USES THEREOF
JP2935113B1 (en) * 1998-09-24 1999-08-16 小林製薬株式会社 Indomethacin transdermal absorbent
WO2000041702A1 (en) 1999-01-13 2000-07-20 Taisho Pharmaceutical Co., Ltd. External steroid preparation
JP2000264899A (en) * 1999-01-13 2000-09-26 Taisho Pharmaceut Co Ltd External preparation of steroid
JP2001139451A (en) * 1999-11-17 2001-05-22 Lion Corp Gelatinous cosmetic
AU2002229663A1 (en) 2000-12-15 2002-06-24 Akzo Nobel N.V. 14(15)-unsaturated 15- and/or 16- substituted androgens with mixed androgen-progestational activity profile
DE10104327A1 (en) * 2001-01-24 2002-07-25 Schering Ag New 11beta-halo-testosterone derivatives useful in male hormone replacement therapy and in male fertility control
DE10107663B4 (en) 2001-02-19 2004-09-09 Lts Lohmann Therapie-Systeme Ag Testosterone-containing transdermal therapeutic system, process for its preparation and its use

Also Published As

Publication number Publication date
EP1875905B1 (en) 2010-05-12
CR8059A (en) 2006-05-29
CN1780610A (en) 2006-05-31
JP2010241824A (en) 2010-10-28
EP1617827A1 (en) 2006-01-25
CO5640075A2 (en) 2006-05-31
WO2004096191A1 (en) 2004-11-11
NO20055601D0 (en) 2005-11-25
EA200501583A1 (en) 2006-06-30
HRP20080178T3 (en) 2008-05-31
JP2006524653A (en) 2006-11-02
CA2523734A1 (en) 2004-11-11
NZ543264A (en) 2010-03-26
ECSP056186A (en) 2006-04-19
KR20060007403A (en) 2006-01-24
AU2004233572B2 (en) 2010-07-15
RS51307B (en) 2010-12-31
AU2004233572A1 (en) 2004-11-11
DE502004011164D1 (en) 2010-06-24
CA2523734C (en) 2009-12-22
TW200524644A (en) 2005-08-01
CN1780610B (en) 2010-06-09
CY1108069T1 (en) 2014-02-12
CL2004000884A1 (en) 2005-03-11
NO20055601L (en) 2006-01-26
BRPI0409918A (en) 2006-04-25
RS20050809A (en) 2007-09-21
JO2492B1 (en) 2009-10-05
NZ583760A (en) 2011-10-28
KR101093999B1 (en) 2011-12-15
PL1617827T3 (en) 2008-07-31
PE20050461A1 (en) 2005-08-13
HK1087633A1 (en) 2006-10-20
EP1875905A2 (en) 2008-01-09
PT1617827E (en) 2008-04-30
EP1617827B1 (en) 2008-02-13
AR044113A1 (en) 2005-08-24
ATE385786T1 (en) 2008-03-15
MXPA05011541A (en) 2006-05-31
JP4829102B2 (en) 2011-12-07
EP1875905A3 (en) 2008-06-25
ES2300763T3 (en) 2008-06-16
TWI343259B (en) 2011-06-11
DE502004006196D1 (en) 2008-03-27
ZA200509549B (en) 2007-02-28
EA008686B1 (en) 2007-06-29
ATE467412T1 (en) 2010-05-15
ES2345458T3 (en) 2010-09-23
UA83036C2 (en) 2008-06-10
SI1617827T1 (en) 2008-06-30

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