NO20054144L - Use of bradykinin-B2 receptor antagonists for the treatment of osteoarthrosis - Google Patents

Use of bradykinin-B2 receptor antagonists for the treatment of osteoarthrosis

Info

Publication number
NO20054144L
NO20054144L NO20054144A NO20054144A NO20054144L NO 20054144 L NO20054144 L NO 20054144L NO 20054144 A NO20054144 A NO 20054144A NO 20054144 A NO20054144 A NO 20054144A NO 20054144 L NO20054144 L NO 20054144L
Authority
NO
Norway
Prior art keywords
bradykinin
diseases
osteoarthrosis
treatment
joint
Prior art date
Application number
NO20054144A
Other languages
Norwegian (no)
Other versions
NO333903B1 (en
Inventor
Karl Rudolphi
Martin Michaelis
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of NO20054144L publication Critical patent/NO20054144L/en
Publication of NO333903B1 publication Critical patent/NO333903B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043Kallidins; Bradykinins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Peptider med bradykinin antagonistiske virking egner seg for fremstilling av legemidler for profilakse og av sykdommer hvis utvikling er forbundet med en forøket aktivitet av matriks-metalkpi.ril hører sykdommer som degenerative leddsykdommer, eksempelvis (N-oon;-trose, spondy.ose saii.L briisksvinn etter leddtraumer eller lengre inaktivitet av ledd etter menisk- eller patellaskader eller håndbrudd.Peptides with bradykinin antagonistic action are suitable for the preparation of drugs for prophylaxis and of diseases whose development is associated with an increased activity of matrix metal chloride, diseases such as degenerative joint diseases, for example (N-oon; L briquette after joint trauma or prolonged inactivity of joint after meniscus or patella injury or hand fracture.

NO20054144A 2003-02-07 2005-09-06 Use of bradykinin-B2 receptor antagonists for the production of pharmaceutical agents for use in the treatment of osteoarthritis NO333903B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10304994A DE10304994A1 (en) 2003-02-07 2003-02-07 The use of antagonists of the bradykinin B2 receptor for the treatment of osteoarthrosis
PCT/EP2004/000550 WO2004069266A2 (en) 2003-02-07 2004-01-23 Use of bradykinin-b2 receptor antagonists for treating osteoarthrosis

Publications (2)

Publication Number Publication Date
NO20054144L true NO20054144L (en) 2005-09-06
NO333903B1 NO333903B1 (en) 2013-10-14

Family

ID=32797325

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054144A NO333903B1 (en) 2003-02-07 2005-09-06 Use of bradykinin-B2 receptor antagonists for the production of pharmaceutical agents for use in the treatment of osteoarthritis

Country Status (31)

Country Link
EP (1) EP1594520B1 (en)
JP (1) JP2006516980A (en)
KR (1) KR20050105447A (en)
CN (1) CN1317029C (en)
AR (1) AR043036A1 (en)
AT (1) ATE335500T1 (en)
AU (1) AU2004210396A1 (en)
BR (1) BRPI0407333A (en)
CA (1) CA2514152C (en)
CO (1) CO5690613A2 (en)
CY (1) CY1105708T1 (en)
DE (2) DE10304994A1 (en)
DK (1) DK1594520T3 (en)
ES (1) ES2268622T3 (en)
HK (1) HK1085926A1 (en)
HR (1) HRP20050701B1 (en)
IL (1) IL169899A0 (en)
MA (1) MA27618A1 (en)
ME (1) MEP41008A (en)
MX (1) MXPA05007310A (en)
MY (1) MY135827A (en)
NO (1) NO333903B1 (en)
NZ (1) NZ541680A (en)
PE (1) PE20040939A1 (en)
PL (1) PL206412B1 (en)
PT (1) PT1594520E (en)
RS (1) RS51029B (en)
RU (1) RU2329057C2 (en)
TW (1) TW200505472A (en)
WO (1) WO2004069266A2 (en)
ZA (1) ZA200505177B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0710522D0 (en) * 2007-06-01 2007-07-11 Royal Veterinary College The Drug delivery system comprising matrix metalloproteinase inhibitors
IT1391236B1 (en) * 2008-07-11 2011-12-01 St Luso Farm D'italia Spa PHARMACEUTICAL COMPOSITIONS BASED ON ANTAGONISTS OF THE B2 KININE AND CORTICOSTEROID RECEPTOR AND THEIR USE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
MX9100717A (en) * 1990-08-24 1992-04-01 Syntex Inc BRADIQUININE ANTAGONISTS
FR2751650B1 (en) * 1996-07-24 1998-10-09 Fournier Ind & Sante NOVEL N-BENZENESULFONYL-L-PROLINE COMPOUNDS, METHOD OF PREPARATION AND THERAPEUTIC USE
CA2364178C (en) * 2000-12-05 2006-01-10 Yasuhiro Katsu N-benzenesulfonyl l-proline compounds as bradykinin antagonists
CA2474645C (en) * 2002-02-01 2011-08-09 Omeros Corporation Compositions and methods for systemic inhibition of cartilage degradation

Also Published As

Publication number Publication date
TW200505472A (en) 2005-02-16
EP1594520A2 (en) 2005-11-16
DE10304994A1 (en) 2004-09-02
HRP20050701A2 (en) 2006-09-30
KR20050105447A (en) 2005-11-04
PL376605A1 (en) 2006-01-09
ATE335500T1 (en) 2006-09-15
HK1085926A1 (en) 2006-09-08
DK1594520T3 (en) 2006-12-11
DE502004001159D1 (en) 2006-09-21
MEP41008A (en) 2011-02-10
NZ541680A (en) 2009-07-31
JP2006516980A (en) 2006-07-13
IL169899A0 (en) 2011-08-01
MXPA05007310A (en) 2005-09-30
CO5690613A2 (en) 2006-10-31
CN1317029C (en) 2007-05-23
HRP20050701B1 (en) 2014-01-03
WO2004069266A3 (en) 2004-09-30
AR043036A1 (en) 2005-07-13
CA2514152C (en) 2012-01-17
NO333903B1 (en) 2013-10-14
ES2268622T3 (en) 2007-03-16
MA27618A1 (en) 2005-11-01
RS51029B (en) 2010-10-31
PT1594520E (en) 2006-11-30
ZA200505177B (en) 2006-11-29
RU2329057C2 (en) 2008-07-20
AU2004210396A1 (en) 2004-08-19
CY1105708T1 (en) 2010-12-22
CN1747742A (en) 2006-03-15
PE20040939A1 (en) 2005-01-17
RU2005127862A (en) 2006-01-27
EP1594520B1 (en) 2006-08-09
MY135827A (en) 2008-07-31
CA2514152A1 (en) 2004-08-19
WO2004069266A2 (en) 2004-08-19
PL206412B1 (en) 2010-08-31
RS20050565A (en) 2007-09-21
BRPI0407333A (en) 2006-01-10

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