MEP41008A - Use of bradykinin-b2 receptor antagonists for treating osteoarthrosis - Google Patents

Use of bradykinin-b2 receptor antagonists for treating osteoarthrosis

Info

Publication number
MEP41008A
MEP41008A MEP-410/08A MEP41008A MEP41008A ME P41008 A MEP41008 A ME P41008A ME P41008 A MEP41008 A ME P41008A ME P41008 A MEP41008 A ME P41008A
Authority
ME
Montenegro
Prior art keywords
bradykinin
receptor antagonists
diseases
treating osteoarthrosis
osteoarthrosis
Prior art date
Application number
MEP-410/08A
Other languages
Bosnian (bs)
Croatian (hr)
Inventor
Martin Michaelis
Karl Rudolphi
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MEP41008A publication Critical patent/MEP41008A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043Kallidins; Bradykinins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Peptidi sa bradikinin-antagonističkim djelovanjem dolaze u obzir za proizvodnju ljekova za profilaksu i terapiju oboljenja, na čiji tok utiče pojačana aktivnost metaloproteinaze matrice.Tu spadaju oboljenja kao što su degenerativna oboljenja zglobova, primjera radi osteoartoza, spondiloza i atrofija hrskavice posle traume zgloba ili dugotrajne imobilizacije zgloba posle oštećenja meniskusa ili čašice koljena ili povrede ligamenata.Peptides with bradykinin-antagonistic activity are considered for the production of drugs for prophylaxis and treatment of diseases, the course of which is affected by increased matrix metalloproteinase activity. These include diseases such as degenerative joint diseases, for example osteoarthritis, spondylosis and cartilage atrophy immobilization of the joint after damage to the meniscus or cup of the knee or injury to the ligaments.

MEP-410/08A 2003-02-07 2004-01-23 Use of bradykinin-b2 receptor antagonists for treating osteoarthrosis MEP41008A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10304994A DE10304994A1 (en) 2003-02-07 2003-02-07 The use of antagonists of the bradykinin B2 receptor for the treatment of osteoarthrosis
PCT/EP2004/000550 WO2004069266A2 (en) 2003-02-07 2004-01-23 Use of bradykinin-b2 receptor antagonists for treating osteoarthrosis
YUP-2005/0565A RS51029B (en) 2003-02-07 2004-01-23 Use of bradykinin-b2 receptor antagonists for treating oseoarthrosis

Publications (1)

Publication Number Publication Date
MEP41008A true MEP41008A (en) 2011-02-10

Family

ID=32797325

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-410/08A MEP41008A (en) 2003-02-07 2004-01-23 Use of bradykinin-b2 receptor antagonists for treating osteoarthrosis

Country Status (31)

Country Link
EP (1) EP1594520B1 (en)
JP (1) JP2006516980A (en)
KR (1) KR20050105447A (en)
CN (1) CN1317029C (en)
AR (1) AR043036A1 (en)
AT (1) ATE335500T1 (en)
AU (1) AU2004210396A1 (en)
BR (1) BRPI0407333A (en)
CA (1) CA2514152C (en)
CO (1) CO5690613A2 (en)
CY (1) CY1105708T1 (en)
DE (2) DE10304994A1 (en)
DK (1) DK1594520T3 (en)
ES (1) ES2268622T3 (en)
HK (1) HK1085926A1 (en)
HR (1) HRP20050701B1 (en)
IL (1) IL169899A0 (en)
MA (1) MA27618A1 (en)
ME (1) MEP41008A (en)
MX (1) MXPA05007310A (en)
MY (1) MY135827A (en)
NO (1) NO333903B1 (en)
NZ (1) NZ541680A (en)
PE (1) PE20040939A1 (en)
PL (1) PL206412B1 (en)
PT (1) PT1594520E (en)
RS (1) RS51029B (en)
RU (1) RU2329057C2 (en)
TW (1) TW200505472A (en)
WO (1) WO2004069266A2 (en)
ZA (1) ZA200505177B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0710522D0 (en) * 2007-06-01 2007-07-11 Royal Veterinary College The Drug delivery system comprising matrix metalloproteinase inhibitors
IT1391236B1 (en) * 2008-07-11 2011-12-01 St Luso Farm D'italia Spa PHARMACEUTICAL COMPOSITIONS BASED ON ANTAGONISTS OF THE B2 KININE AND CORTICOSTEROID RECEPTOR AND THEIR USE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
MX9100717A (en) * 1990-08-24 1992-04-01 Syntex Inc BRADIQUININE ANTAGONISTS
FR2751650B1 (en) * 1996-07-24 1998-10-09 Fournier Ind & Sante NOVEL N-BENZENESULFONYL-L-PROLINE COMPOUNDS, METHOD OF PREPARATION AND THERAPEUTIC USE
CA2364178C (en) * 2000-12-05 2006-01-10 Yasuhiro Katsu N-benzenesulfonyl l-proline compounds as bradykinin antagonists
EP1496835A4 (en) * 2002-02-01 2006-10-18 Omeros Corp Compositions and methods for systemic inhibition of cartilage degradation

Also Published As

Publication number Publication date
DK1594520T3 (en) 2006-12-11
HK1085926A1 (en) 2006-09-08
JP2006516980A (en) 2006-07-13
HRP20050701A2 (en) 2006-09-30
EP1594520B1 (en) 2006-08-09
BRPI0407333A (en) 2006-01-10
CN1747742A (en) 2006-03-15
ZA200505177B (en) 2006-11-29
MA27618A1 (en) 2005-11-01
TW200505472A (en) 2005-02-16
PL376605A1 (en) 2006-01-09
NO20054144L (en) 2005-09-06
AU2004210396A1 (en) 2004-08-19
CY1105708T1 (en) 2010-12-22
NO333903B1 (en) 2013-10-14
CO5690613A2 (en) 2006-10-31
DE502004001159D1 (en) 2006-09-21
WO2004069266A3 (en) 2004-09-30
DE10304994A1 (en) 2004-09-02
IL169899A0 (en) 2011-08-01
HRP20050701B1 (en) 2014-01-03
PL206412B1 (en) 2010-08-31
AR043036A1 (en) 2005-07-13
PE20040939A1 (en) 2005-01-17
PT1594520E (en) 2006-11-30
CA2514152A1 (en) 2004-08-19
RS20050565A (en) 2007-09-21
RS51029B (en) 2010-10-31
RU2005127862A (en) 2006-01-27
MY135827A (en) 2008-07-31
ES2268622T3 (en) 2007-03-16
RU2329057C2 (en) 2008-07-20
EP1594520A2 (en) 2005-11-16
CN1317029C (en) 2007-05-23
ATE335500T1 (en) 2006-09-15
WO2004069266A2 (en) 2004-08-19
MXPA05007310A (en) 2005-09-30
CA2514152C (en) 2012-01-17
NZ541680A (en) 2009-07-31
KR20050105447A (en) 2005-11-04

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