NO20045536L - Inhibitorer av inflammatorisk genaktivitet og kolesterol-biosyntese - Google Patents

Inhibitorer av inflammatorisk genaktivitet og kolesterol-biosyntese

Info

Publication number
NO20045536L
NO20045536L NO20045536A NO20045536A NO20045536L NO 20045536 L NO20045536 L NO 20045536L NO 20045536 A NO20045536 A NO 20045536A NO 20045536 A NO20045536 A NO 20045536A NO 20045536 L NO20045536 L NO 20045536L
Authority
NO
Norway
Prior art keywords
inhibitors
gene activity
cholesterol biosynthesis
methods
inflammatory gene
Prior art date
Application number
NO20045536A
Other languages
English (en)
Norwegian (no)
Inventor
Mark J Evans
Douglas C Harnish
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2003/018651 external-priority patent/WO2003106632A2/fr
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20045536L publication Critical patent/NO20045536L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
NO20045536A 2002-06-13 2004-12-17 Inhibitorer av inflammatorisk genaktivitet og kolesterol-biosyntese NO20045536L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38791502P 2002-06-13 2002-06-13
US47018803P 2003-05-14 2003-05-14
PCT/US2003/018651 WO2003106632A2 (fr) 2002-06-13 2003-06-13 Inhibiteurs de l'activite genique inflammatoire et de la synthese de cholesterol

Publications (1)

Publication Number Publication Date
NO20045536L true NO20045536L (no) 2005-02-28

Family

ID=34425702

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20045536A NO20045536L (no) 2002-06-13 2004-12-17 Inhibitorer av inflammatorisk genaktivitet og kolesterol-biosyntese

Country Status (10)

Country Link
US (1) US20050221328A1 (fr)
EP (1) EP1560925A4 (fr)
JP (1) JP2006505249A (fr)
KR (1) KR20050010916A (fr)
CN (1) CN1675376A (fr)
BR (1) BR0311772A (fr)
CA (1) CA2489594A1 (fr)
EA (1) EA200500012A1 (fr)
MX (1) MXPA04012560A (fr)
NO (1) NO20045536L (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090137516A1 (en) * 2007-11-05 2009-05-28 Wyeth Compositions and methods of treating dyslipidemia
WO2009141926A1 (fr) * 2008-05-23 2009-11-26 国立大学法人東京大学 Procédé d'acquisition d'un composé capable d'agir sur le métabolisme du glucose/métabolisme lipidique
RU2705249C2 (ru) * 2013-07-12 2019-11-06 Дзе Чилдрен'З Хоспитал Оф Филадельфия Вектор aav и анализ на нейтрализующие антитела против aav (аденоассоциированного вируса)
US10301268B2 (en) * 2014-03-13 2019-05-28 The Salk Institute For Biological Studies Analogs of fexaramine and methods of making and using
US20230174951A1 (en) * 2020-04-26 2023-06-08 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization Phenol-rich grapes
CN114022409B (zh) * 2021-09-30 2023-04-18 电子科技大学 基于深度学习的包覆药表面缺陷检测算法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753431A (en) * 1993-10-13 1998-05-19 Northeastern Ohio University Cholesterol 7 α-hydroxdylase gene regulatory elements and transcription factors
US5728548A (en) * 1995-06-29 1998-03-17 Genetics Institute, Inc. Retinoid receptor-1 (RR1) and DNA encoding RR1
US6316181B1 (en) * 1998-04-24 2001-11-13 Virginia Commonwealth University Establishment of cell lines with persistent expression of a green fluorescent protein (GFP) using a pIRES/EGFP DNA vector construct
US20030083484A1 (en) * 2001-07-31 2003-05-01 Crooke Rosanne M. Antisense modulation of short heterodimer partner-1 expression
AU4948800A (en) * 1999-05-24 2000-12-12 Sankyo Company Limited Method for searching physiologically active substance
WO2001053312A1 (fr) * 1999-12-23 2001-07-26 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides
WO2001079224A2 (fr) * 2000-04-12 2001-10-25 Genaissance Pharmaceuticals, Inc. Haplotypes du gene cyp8b1
AU2001280974A1 (en) * 2000-07-31 2002-02-13 Glaxo Group Limited Identification of new therapeutic targets for modulating bile acid synthesis
US6878751B1 (en) * 2000-10-19 2005-04-12 Imperial College Of Science Technology And Medicine Administration of resveratrol to treat inflammatory respiratory disorders

Also Published As

Publication number Publication date
CA2489594A1 (fr) 2003-12-24
EP1560925A2 (fr) 2005-08-10
US20050221328A1 (en) 2005-10-06
CN1675376A (zh) 2005-09-28
KR20050010916A (ko) 2005-01-28
JP2006505249A (ja) 2006-02-16
EP1560925A4 (fr) 2006-10-25
MXPA04012560A (es) 2005-10-19
BR0311772A (pt) 2007-05-08
EA200500012A1 (ru) 2006-04-28

Similar Documents

Publication Publication Date Title
DE60336901D1 (de) Chinazolinon modulatoren von nukleinrezeptoren
NO981903L (no) SmÕ-molekylµre inhibitorer for rotamase enzymaktivitet
TW200531679A (en) Methods of modulating cytokine activity; related reagents
WO2003080803A3 (fr) Procedes d'utilisation d'agonistes du recepteur farnesoide x (fxr)
TR200103428T2 (tr) IMPDH enzim inhibitörleri.
NO20052595L (no) Sammensetninger anvendelige som inhibitorer av ROCK- og andre proteinkinaser.
NO20064976L (no) Azanidoler som er nyttige som inhibitorer av rock og andre proteinkinaser
MX2007004841A (es) Triazoles utiles como inhibidores de proteinas cinasas.
HK1098047A1 (en) Indole derivatives and use thereof as kinase inhibitors in particular ikk2 inhibitors
NO20052888L (no) Diamintriazoler anvendelige som inhibitorer av proteinkinaser
NO20061194L (no) Mitotiske kinesininbibitorer
NO20001583D0 (no) Stimulering av hematopoetiske celler in vitro
EA200700118A1 (ru) Амидосоединения и их применение в качестве лекарственных средств
WO2005001079A3 (fr) Reparation et regeneration des tissus mous a l'aide de cellules provenant de tissus post-partum
ZA200509753B (en) High protein, low carbohydrate pet food composition comprising non-fermentable fiber
EA200700251A1 (ru) Амидосоединения и их применение в качестве фармацевтических средств
WO2006055752A3 (fr) INHIBITEURS DE LA 11-β-HYDROXYSTEROIDE DEHYDROGENASE DE TYPE 1 ET PROCEDES D’UTILISATION
SG161286A1 (en) Methods for treating and preventing fibrosis by il-21 / il-21r antagonists
NO991433L (no) Heterosykliske estere og amider
WO2008060813A3 (fr) Anticorps antagonistes de haute affinité dirigés contre le récepteur alpha 1 de l'interleukine-13
LV12125A (lv) Ciklofilina rotamazes aktivitates inhibitori
WO2006071777A3 (fr) Reparation et regeneration de tissus mous au moyen de cellules derivees du post-partum et produits cellulaires
NO20014230D0 (no) Metoder og preparater som anvender (+) noreisaprid i kombinasjon med protonpumpeinhibitorer eller H2 reseptor-antagonister
NO20045536L (no) Inhibitorer av inflammatorisk genaktivitet og kolesterol-biosyntese
DK1509618T3 (da) Autoimmune sygdomme og NADPH-oxidasedefekter

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application