NO20042635L - 5-Sulfanyl-ñH-1,2,4-triazol-derivater og deres anvendelse som medisin - Google Patents
5-Sulfanyl-ñH-1,2,4-triazol-derivater og deres anvendelse som medisinInfo
- Publication number
- NO20042635L NO20042635L NO20042635A NO20042635A NO20042635L NO 20042635 L NO20042635 L NO 20042635L NO 20042635 A NO20042635 A NO 20042635A NO 20042635 A NO20042635 A NO 20042635A NO 20042635 L NO20042635 L NO 20042635L
- Authority
- NO
- Norway
- Prior art keywords
- sulfanyl
- medicine
- triazole derivatives
- triazole
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0115342A FR2832710B1 (fr) | 2001-11-28 | 2001-11-28 | Derives de 5-sulfanyl-4h-1,2,4-triazoles et leur utilisation en tant que medicaments |
FR0207697 | 2002-06-21 | ||
PCT/FR2002/004055 WO2003045926A1 (fr) | 2001-11-28 | 2002-11-27 | Derives de 5-sulfanyl-4h-1,2,4-triazoles et leur utilisation en tant que medicament |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20042635L true NO20042635L (no) | 2004-06-23 |
Family
ID=26213278
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20042635A NO20042635L (no) | 2001-11-28 | 2004-06-23 | 5-Sulfanyl-ñH-1,2,4-triazol-derivater og deres anvendelse som medisin |
Country Status (23)
Country | Link |
---|---|
US (1) | US20050154039A1 (de) |
EP (1) | EP1465880B1 (de) |
JP (1) | JP2005513035A (de) |
KR (1) | KR100961332B1 (de) |
CN (1) | CN100462359C (de) |
AR (1) | AR037465A1 (de) |
AT (1) | ATE438630T1 (de) |
AU (1) | AU2002361345B8 (de) |
BR (1) | BR0214553A (de) |
CA (1) | CA2468184A1 (de) |
CZ (1) | CZ2004760A3 (de) |
DE (1) | DE60233265D1 (de) |
ES (1) | ES2330927T3 (de) |
HK (1) | HK1070361A1 (de) |
HU (1) | HUP0402489A3 (de) |
MX (1) | MXPA04005099A (de) |
MY (1) | MY133406A (de) |
NO (1) | NO20042635L (de) |
NZ (1) | NZ533397A (de) |
PL (1) | PL370140A1 (de) |
RU (1) | RU2367655C2 (de) |
TW (1) | TWI283670B (de) |
WO (1) | WO2003045926A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
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TWI332943B (en) * | 2001-07-10 | 2010-11-11 | Synta Pharmaceuticals Corp | Taxol enhancer compounds |
TWI297335B (en) | 2001-07-10 | 2008-06-01 | Synta Pharmaceuticals Corp | Taxol enhancer compounds |
TWI252847B (en) * | 2001-07-10 | 2006-04-11 | Synta Pharmaceuticals Corp | Synthesis of taxol enhancers |
TWI330079B (en) * | 2003-01-15 | 2010-09-11 | Synta Pharmaceuticals Corp | Treatment for cancers |
RS52999B (en) * | 2004-06-23 | 2014-02-28 | Synta Pharmaceuticals Corp. | BIS (AMIDIDA TIO-HYDRAZIDE) Salts for Cancer Treatment |
NZ555158A (en) | 2004-11-18 | 2010-09-30 | Synta Pharmaceuticals Corp | Triazole compounds that modulate Hsp90 activity |
CA2604907A1 (en) * | 2005-04-15 | 2006-10-26 | Synta Pharmaceuticals Corp. | Combination cancer therapy with bis(thiohydrazide) amide compounds |
AU2006338265B2 (en) * | 2005-08-18 | 2011-04-14 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate HSP90 activity |
AU2007267847B2 (en) | 2006-05-25 | 2012-04-12 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate Hsp90 activity |
AU2007267852A1 (en) * | 2006-05-25 | 2007-12-06 | Synta Pharmaceuticals Corp. | Compounds that modulate Hsp90 activity and methods for identifying same |
US8034834B2 (en) | 2006-05-25 | 2011-10-11 | Synta Pharmaceuticals Corp. | Method for treating proliferative disorders with HSP90 inhibitors |
KR20090045354A (ko) | 2006-08-21 | 2009-05-07 | 신타 파마슈티칼스 코프. | 증식성 장애를 치료하기 위한 화합물 |
AU2007290490B2 (en) * | 2006-08-31 | 2011-09-08 | Synta Pharmaceuticals Corp. | Combination with bis(thiohydrazide amides) for treating cancer |
JP2010527367A (ja) * | 2007-05-15 | 2010-08-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ウロテンシンii受容体アンタゴニスト |
KR100980328B1 (ko) * | 2007-12-14 | 2010-09-06 | 한국생명공학연구원 | 단백질 포스파타제의 활성을 억제하는트리아졸릴-티오-에타논 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 암 예방 및 치료용조성물 |
CA2719721C (en) | 2008-03-26 | 2012-12-18 | Daiichi Sankyo Company, Limited | Tetrahydroisoquinoline derivative |
CN101684103B (zh) * | 2008-09-22 | 2011-04-06 | 天津药物研究院 | 1,2,4-三唑结构的化合物、其制备方法和用途 |
WO2010093845A1 (en) | 2009-02-12 | 2010-08-19 | Exelixis, Inc. | Triazole and imidazole derivatives for use as tgr5 agonists in the treatment of diabetes and obesity |
US9205086B2 (en) | 2010-04-19 | 2015-12-08 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of a Hsp90 inhibitory compounds and a EGFR inhibitor |
WO2013067162A1 (en) | 2011-11-02 | 2013-05-10 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of hsp90 inhibitors with topoisomerase i inhibitors |
US20140286902A1 (en) | 2011-11-02 | 2014-09-25 | Synta Pharmaceuticals Corp. | Combination therapy of hsp90 inhibitors with platinum-containing agents |
JP2014533299A (ja) | 2011-11-14 | 2014-12-11 | シンタ ファーマシューティカルズ コーポレーション | Braf阻害剤とhsp90阻害剤の組合せ療法 |
US9598395B2 (en) | 2012-03-23 | 2017-03-21 | The Regents Of The University Of California | Premature-termination-codons readthrough compounds |
CN103755652B (zh) * | 2013-12-20 | 2015-08-05 | 陕西理工学院 | 一种磺酰胺类化合物及其应用 |
CN104370844A (zh) * | 2014-10-29 | 2015-02-25 | 广西师范大学 | 3-硫酮-5-巯基甲基-1,2,4-三唑的合成方法 |
CN106831529A (zh) * | 2016-12-11 | 2017-06-13 | 湖南华腾制药有限公司 | 一种三氟甲基吲哚衍生物的制备方法 |
KR20190114986A (ko) | 2017-02-08 | 2019-10-10 | 오노 야꾸힝 고교 가부시키가이샤 | 소마토스타틴 수용체 작동 활성을 갖는 화합물 및 그 의약 용도 |
US11912687B2 (en) | 2017-05-12 | 2024-02-27 | Board of Trustees of the Southern Illinois University | 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof |
JP7343170B2 (ja) * | 2017-05-12 | 2023-09-12 | ボード オブ トラスティーズ オブ ザ サザン イリノイ ユニバーシティ オン ビハーフ オブ サザン イリノイ ユニバーシティ エドワーズビル | 3,4,5-三置換-1,2,4-トリアゾールおよび3,4,5-三置換-3-チオ-1,2,4-トリアゾール、ならびにそれらの使用 |
CN109666022B (zh) * | 2017-10-17 | 2021-06-15 | 中国科学院上海药物研究所 | 三氮唑衍生物及其制备方法和用途 |
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EP0409332A3 (en) * | 1989-07-19 | 1991-08-07 | Merck & Co. Inc. | Substituted triazoles as angiotensin ii antagonists |
US5177095A (en) * | 1990-02-13 | 1993-01-05 | Merck & Co., Inc. | Triazole angiotensin II antagonists incorporating a substituted benzyl element |
GB2263635A (en) * | 1992-01-28 | 1993-08-04 | Merck & Co Inc | Substitiuted triazoles as neurotensin antagonists |
WO1995013268A1 (en) * | 1993-11-12 | 1995-05-18 | Gyógyszerkutató Intézet Kft. | Ulcer-inhibiting triazole derivatives, pharmaceutical compositions containing them and process for preparing same |
US6080772A (en) * | 1995-06-07 | 2000-06-27 | Sugen, Inc. | Thiazole compounds and methods of modulating signal transduction |
DE19600934A1 (de) * | 1996-01-12 | 1997-07-17 | Basf Ag | Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung |
CA2293400A1 (en) * | 1997-06-13 | 1998-12-17 | Gerald Mcmahon | Novel heteroaryl compounds for the modulation of protein tyrosine enzyme related cellular signal transduction |
CA2334945A1 (en) * | 1998-06-12 | 1999-12-16 | Christophe Alain Thurieau | Imidazolyl derivatives |
FR2796945B1 (fr) * | 1999-07-30 | 2002-06-28 | Sod Conseils Rech Applic | Nouveaux derives d'hydantoines, de thiohydantoines, de pyrimidinediones et de thioxopyrimidinones, leurs procedes de preparation et leur application a titre de medicaments |
FR2802206B1 (fr) * | 1999-12-14 | 2005-04-22 | Sod Conseils Rech Applic | Derives de 4-aminopiperidine et leur utilisation en tant que medicament |
PL359340A1 (en) * | 2000-05-19 | 2004-08-23 | Triazole derivatives |
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- 2002-11-27 PL PL02370140A patent/PL370140A1/xx not_active Application Discontinuation
- 2002-11-27 TW TW091134432A patent/TWI283670B/zh active
- 2002-11-27 ES ES02796876T patent/ES2330927T3/es not_active Expired - Lifetime
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- 2002-11-27 RU RU2004119406/04A patent/RU2367655C2/ru not_active IP Right Cessation
- 2002-11-27 KR KR1020047008002A patent/KR100961332B1/ko not_active IP Right Cessation
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- 2002-11-27 CA CA002468184A patent/CA2468184A1/fr not_active Abandoned
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- 2002-11-27 WO PCT/FR2002/004055 patent/WO2003045926A1/fr active IP Right Grant
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JP2005513035A (ja) | 2005-05-12 |
TWI283670B (en) | 2007-07-11 |
RU2367655C2 (ru) | 2009-09-20 |
KR100961332B1 (ko) | 2010-06-04 |
NZ533397A (en) | 2005-12-23 |
CN1617859A (zh) | 2005-05-18 |
MXPA04005099A (es) | 2004-08-19 |
AR037465A1 (es) | 2004-11-10 |
AU2002361345A1 (en) | 2003-06-10 |
US20050154039A1 (en) | 2005-07-14 |
KR20040062969A (ko) | 2004-07-09 |
CZ2004760A3 (cs) | 2005-01-12 |
HUP0402489A2 (hu) | 2005-05-30 |
TW200300760A (en) | 2003-06-16 |
MY133406A (en) | 2007-11-30 |
EP1465880B1 (de) | 2009-08-05 |
BR0214553A (pt) | 2004-10-13 |
HK1070361A1 (en) | 2005-06-17 |
ES2330927T3 (es) | 2009-12-17 |
CN100462359C (zh) | 2009-02-18 |
EP1465880A1 (de) | 2004-10-13 |
HUP0402489A3 (en) | 2009-09-28 |
ATE438630T1 (de) | 2009-08-15 |
CA2468184A1 (fr) | 2003-06-05 |
AU2002361345B8 (en) | 2008-06-26 |
RU2004119406A (ru) | 2005-05-10 |
DE60233265D1 (de) | 2009-09-17 |
PL370140A1 (en) | 2005-05-16 |
AU2002361345B2 (en) | 2008-06-05 |
WO2003045926A1 (fr) | 2003-06-05 |
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