NO20040389L - New vinyl carboxylic acid derivatives and their use as antidiabetics - Google Patents

New vinyl carboxylic acid derivatives and their use as antidiabetics

Info

Publication number
NO20040389L
NO20040389L NO20040389A NO20040389A NO20040389L NO 20040389 L NO20040389 L NO 20040389L NO 20040389 A NO20040389 A NO 20040389A NO 20040389 A NO20040389 A NO 20040389A NO 20040389 L NO20040389 L NO 20040389L
Authority
NO
Norway
Prior art keywords
antidiabetics
carboxylic acid
acid derivatives
vinyl carboxylic
new vinyl
Prior art date
Application number
NO20040389A
Other languages
Norwegian (no)
Inventor
Lone Jeppesen
Per Sauerberg
Ingrid Pettersson
Paul Stanley Bury
John Patrick Mogensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO20040389L publication Critical patent/NO20040389L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes
NO20040389A 2001-07-30 2004-01-29 New vinyl carboxylic acid derivatives and their use as antidiabetics NO20040389L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101154 2001-07-30
PCT/DK2002/000471 WO2003011807A1 (en) 2001-07-30 2002-07-05 Novel vinyl carboxylic acid derivatives and their use as antidiabetics etc.

Publications (1)

Publication Number Publication Date
NO20040389L true NO20040389L (en) 2004-01-29

Family

ID=8160643

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20040389A NO20040389L (en) 2001-07-30 2004-01-29 New vinyl carboxylic acid derivatives and their use as antidiabetics

Country Status (15)

Country Link
EP (1) EP1414778A1 (en)
JP (1) JP2004536150A (en)
KR (1) KR20040019087A (en)
CN (1) CN1537093A (en)
BR (1) BR0211414A (en)
CA (1) CA2452665A1 (en)
CZ (1) CZ2004133A3 (en)
HU (1) HUP0401575A2 (en)
IL (1) IL159547A0 (en)
MX (1) MXPA04000891A (en)
NO (1) NO20040389L (en)
PL (1) PL366401A1 (en)
RU (1) RU2004105956A (en)
WO (1) WO2003011807A1 (en)
ZA (1) ZA200400161B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0314335A (en) * 2002-09-05 2005-07-26 Novo Nordisk As Compound, use thereof, pharmaceutical composition, and methods for treating and / or preventing nuclear receptor-mediated conditions, and of type i diabetes, type ii diabetes, impaired glucose tolerance, insulin resistance, or obesity.
ATE469882T1 (en) * 2002-10-28 2010-06-15 High Point Pharmaceuticals Llc NEW COMPOUNDS SUITABLE FOR THE TREATMENT OF PPAR-MEDIATED DISEASES
ATE472526T1 (en) * 2002-10-28 2010-07-15 High Point Pharmaceuticals Llc NEW COMPOUNDS AND THEIR USE AS PPAR MODULATORS
ITRM20030305A1 (en) * 2003-06-20 2004-12-21 Sigma Tau Ind Farmaceuti PREPARATION OF NEW DERIVATIVES OF FENYL ACID OR PHENOXYKYL MONO AND DIACARBOXY USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA AND TYPICAL HYPERTRIGLYCERIDEMIA OF TYPE II DIABETES.
EA012241B1 (en) 2003-09-19 2009-08-28 Янссен Фармацевтика, Н.В. 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs thereof
ES2555031T3 (en) 2003-09-19 2015-12-28 Janssen Pharmaceutica N.V. Acids and analogs 4 - ((phenoxyalkyl) thio) -phenoxyacetics
WO2005105736A1 (en) 2004-05-05 2005-11-10 Novo Nordisk A/S Novel compounds, their preparation and use
JO3006B1 (en) 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv Novel Lysine Salts of 4-((Phenoxy Alkyl)Thio)-Phenoxy Acetic Acid Derivatives
PE20070522A1 (en) 2005-09-14 2007-07-11 Takeda Pharmaceutical 2- [6- (3-AMINO-PIPERIDIN-1-IL) -3-METHYL-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-ILMETHYL] -4-FLUORO-BENZONITRILE AS INHIBITOR OF DIPEPTIDIL PEPTIDASE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
CA2622642C (en) 2005-09-16 2013-12-31 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP2386540A1 (en) 2005-12-22 2011-11-16 High Point Pharmaceuticals, LLC Novel compounds, their preparation and use
PE20080188A1 (en) 2006-04-18 2008-03-10 Janssen Pharmaceutica Nv DERIVATIVES OF BENZOAZEPINE-OXY-ACETIC ACID AS PPAR-DELTA AGONISTS USED TO INCREASE HDL-C, REDUCE LDL-C AND REDUCE CHOLESTEROL
KR100693132B1 (en) * 2006-06-23 2007-03-14 동해전장 주식회사 Relay operation checking device of junction box
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US20120168303A1 (en) * 2011-01-05 2012-07-05 Sueng-Nien Kao Salt water activated emergency lighting device
CN103467408B (en) * 2013-09-03 2015-01-21 浙江医药高等专科学校 Tetrazole carboxylic acid compounds and application thereof
CN103467405B (en) * 2013-09-03 2015-01-07 浙江医药高等专科学校 Tetrazole carboxylic acid compounds, and preparation method and application thereof
CN103467406B (en) * 2013-09-03 2014-12-17 浙江医药高等专科学校 Halogen-substituted tetrazole carboxylic acid compounds, and preparation method and application thereof
CN103467407B (en) * 2013-09-03 2015-04-22 浙江医药高等专科学校 Tetrazole carboxylic acid compounds and application thereof
CN103467409B (en) * 2013-09-03 2015-01-07 浙江医药高等专科学校 Substituted tetrazole carboxylic acid compounds and application thereof
US11267795B2 (en) 2020-07-22 2022-03-08 Reneo Pharmaceuticals, Inc. Crystalline PPAR-delta agonist
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3373467D1 (en) * 1982-06-14 1987-10-15 Takeda Chemical Industries Ltd Vinyl carboxylic acid derivatives, their production and use
AU2652397A (en) * 1996-05-13 1997-12-05 Nippon Shinyaku Co. Ltd. Substituted ethylene compounds and drugs
CZ20013558A3 (en) * 1999-04-20 2002-05-15 Novo Nordisk A/S Compound, pharmaceutical preparation, treatment method, preparation and use thereof
CN1396903A (en) * 2000-01-28 2003-02-12 诺沃挪第克公司 Novel compound, their preparation and use

Also Published As

Publication number Publication date
ZA200400161B (en) 2004-08-18
WO2003011807A1 (en) 2003-02-13
EP1414778A1 (en) 2004-05-06
JP2004536150A (en) 2004-12-02
MXPA04000891A (en) 2004-05-21
RU2004105956A (en) 2005-03-27
PL366401A1 (en) 2005-01-24
HUP0401575A2 (en) 2004-11-29
CA2452665A1 (en) 2003-02-13
CN1537093A (en) 2004-10-13
BR0211414A (en) 2004-08-17
CZ2004133A3 (en) 2004-06-16
IL159547A0 (en) 2004-06-01
KR20040019087A (en) 2004-03-04

Similar Documents

Publication Publication Date Title
NO20040389L (en) New vinyl carboxylic acid derivatives and their use as antidiabetics
NO20030302L (en) New heteroaryl derivatives and their use as drugs
NO20030298D0 (en) Novel heteroaryl derivatives and their use as pharmaceutical agents
DK1347955T3 (en) New almond acid derivatives and their use as throbin inhibitors
DK1373224T3 (en) Novel spirotric cyclic derivatives and their use as phosphodiesterase 7 inhibitors
NO20040680L (en) New dihydropterinone processes for their preparation and their use as a drug
NO20030301D0 (en) New heteroaryl derivatives and their use as pharmaceuticals
NO20053569L (en) Substituted 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazine derivatives and their use as neurokinin antagonists
NO2014005I1 (en) olodaterol, acid addition salts and pharmacologically acceptable acids thereof
NO20015113L (en) New compounds, their preparation and use
DK1501815T3 (en) Substituted phenylacetamides and their use as glucokinase activators
NO20034669L (en) Carboxylic acid derivative and salt thereof
NO20033566D0 (en) Acylated 6,7,8,9-tetrehydro-5H-benzocycloheptenylamines and their use as pharmaceutical agents
NO20042495L (en) New benzophenone derivatives or salts thereof
NO20042635L (en) 5-Sulfanyl-HH-1,2,4-triazole derivatives and their use as medicine
NO20034970D0 (en) New arylheteroalkylamine derivatives
NO20052124D0 (en) New 1,4-diazabicycloalkane derivatives, their preparation and use
NO20035694D0 (en) New sulfonic acid derivatives
DK1429769T3 (en) New formulations and their use
NO20030382D0 (en) New indole derivatives and their use as drugs
DK1387838T3 (en) Cyanoanthranylamide derivatives and their use as drugs
DK1525193T3 (en) Acylaminothiazole derivatives, their preparation and their therapeutic use
DK1150996T3 (en) Novel amidinobenzylamine derivatives and their use as thrombin inhibitors
DK1551814T3 (en) Chiral oxazole-arylpropionic acid derivatives and their use as ppar agnists
DK1531675T3 (en) Agents containing carboxylic acid and their use in plant cultivation

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application