ITRM20030305A1 - PREPARATION OF NEW DERIVATIVES OF FENYL ACID OR PHENOXYKYL MONO AND DIACARBOXY USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA AND TYPICAL HYPERTRIGLYCERIDEMIA OF TYPE II DIABETES. - Google Patents

PREPARATION OF NEW DERIVATIVES OF FENYL ACID OR PHENOXYKYL MONO AND DIACARBOXY USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA AND TYPICAL HYPERTRIGLYCERIDEMIA OF TYPE II DIABETES.

Info

Publication number
ITRM20030305A1
ITRM20030305A1 IT000305A ITRM20030305A ITRM20030305A1 IT RM20030305 A1 ITRM20030305 A1 IT RM20030305A1 IT 000305 A IT000305 A IT 000305A IT RM20030305 A ITRM20030305 A IT RM20030305A IT RM20030305 A1 ITRM20030305 A1 IT RM20030305A1
Authority
IT
Italy
Prior art keywords
phenoxykyl
diacarboxy
fenyl
hyperglycaemia
hypertriglyceridemia
Prior art date
Application number
IT000305A
Other languages
Italian (it)
Inventor
Uomo Natalina Dell
Fabio Giannessi
Pompeo Pessotto
Claudio Pisano
Emanuela Tassoni
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT000305A priority Critical patent/ITRM20030305A1/en
Publication of ITRM20030305A0 publication Critical patent/ITRM20030305A0/en
Priority to PCT/IT2004/000132 priority patent/WO2004113266A1/en
Publication of ITRM20030305A1 publication Critical patent/ITRM20030305A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT000305A 2003-06-20 2003-06-20 PREPARATION OF NEW DERIVATIVES OF FENYL ACID OR PHENOXYKYL MONO AND DIACARBOXY USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA AND TYPICAL HYPERTRIGLYCERIDEMIA OF TYPE II DIABETES. ITRM20030305A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT000305A ITRM20030305A1 (en) 2003-06-20 2003-06-20 PREPARATION OF NEW DERIVATIVES OF FENYL ACID OR PHENOXYKYL MONO AND DIACARBOXY USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA AND TYPICAL HYPERTRIGLYCERIDEMIA OF TYPE II DIABETES.
PCT/IT2004/000132 WO2004113266A1 (en) 2003-06-20 2004-03-19 Derivatives of phenylalkyl and phenoxyalkyl acids for the treatment of the hyperglycaemia and hypertriglyceridaemia and type 2 diabetes and process for preparing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000305A ITRM20030305A1 (en) 2003-06-20 2003-06-20 PREPARATION OF NEW DERIVATIVES OF FENYL ACID OR PHENOXYKYL MONO AND DIACARBOXY USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA AND TYPICAL HYPERTRIGLYCERIDEMIA OF TYPE II DIABETES.

Publications (2)

Publication Number Publication Date
ITRM20030305A0 ITRM20030305A0 (en) 2003-06-20
ITRM20030305A1 true ITRM20030305A1 (en) 2004-12-21

Family

ID=29765878

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000305A ITRM20030305A1 (en) 2003-06-20 2003-06-20 PREPARATION OF NEW DERIVATIVES OF FENYL ACID OR PHENOXYKYL MONO AND DIACARBOXY USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA AND TYPICAL HYPERTRIGLYCERIDEMIA OF TYPE II DIABETES.

Country Status (2)

Country Link
IT (1) ITRM20030305A1 (en)
WO (1) WO2004113266A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10221138B2 (en) * 2013-06-27 2019-03-05 Lg Chem, Ltd. Biaryl derivatives as GPR120 agonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2158064A (en) * 1936-07-01 1939-05-16 Du Pont Polyamides and their production
DE1214238B (en) * 1953-09-14 1966-04-14 Goodrich Co B F Process for the preparation of cyclically substituted 1, 1-dicyanaethanes
GB970969A (en) * 1963-08-15 1964-09-23 Shell Int Research Dicarboxylic acids and their esters and a process for the preparation thereof
FR2331336A1 (en) * 1975-11-14 1977-06-10 Rolland Sa A OXY-4,4'BIS ACIDS (2-PHENOXY ALKANOCARBOXYLIC), THEIR DERIVATIVES AND THEIR APPLICATION AS A MEDICINAL PRODUCT
MXPA02007286A (en) * 2000-01-28 2002-11-29 Novo Nordisk As Propionic acid derivatives and their use in the treatment of diabetes and obesity.
EP1276710A1 (en) * 2000-04-17 2003-01-22 Novo Nordisk A/S New compounds, their preparation and use
RU2004105956A (en) * 2001-07-30 2005-03-27 Ново Нордиск А/С (DK) NEW VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR APPLICATION AS ANTI-DIABETIC MEDICINES, etc.

Also Published As

Publication number Publication date
WO2004113266A1 (en) 2004-12-29
ITRM20030305A0 (en) 2003-06-20

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