NO20013384L - Imidazo [4,5-c] pyridine-4-one derivatives - Google Patents

Imidazo [4,5-c] pyridine-4-one derivatives

Info

Publication number
NO20013384L
NO20013384L NO20013384A NO20013384A NO20013384L NO 20013384 L NO20013384 L NO 20013384L NO 20013384 A NO20013384 A NO 20013384A NO 20013384 A NO20013384 A NO 20013384A NO 20013384 L NO20013384 L NO 20013384L
Authority
NO
Norway
Prior art keywords
imidazo
pyridine
derivatives
prophylaxis
inhibitors
Prior art date
Application number
NO20013384A
Other languages
Norwegian (no)
Other versions
NO20013384D0 (en
Inventor
Werner Mederski
Horst Juraszyk
Hanns Wurziger
Christos Tsaklakidis
Dieter Dorsch
Sabine Bernotat-Danielowski
Guido Melzer
Soheila Anzali
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20013384D0 publication Critical patent/NO20013384D0/en
Publication of NO20013384L publication Critical patent/NO20013384L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Nye forbindelser med formel (I) hvor R, R1, R2, RJ og n har de i krav l angitte betydninger, er inhibitorer for koagulasjonsfaktor Xa og kan anven- des til profylakse og/eller behandling av tromboemboliske sykdommer.Novel compounds of formula (I) wherein R, R1, R2, RJ and n have the meanings set forth in claim 1, are inhibitors of coagulation factor Xa and can be used for the prophylaxis and / or treatment of thromboembolic diseases.

NO20013384A 1999-01-08 2001-07-06 Imidazo [4,5-c] pyridine-4-one derivatives NO20013384L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19900471A DE19900471A1 (en) 1999-01-08 1999-01-08 Imidazo [4,5c] pyridin-4-one derivatives
PCT/EP1999/010236 WO2000040583A2 (en) 1999-01-08 1999-12-21 Imidazo[4,5-c]-pyridine-4-on-derivatives

Publications (2)

Publication Number Publication Date
NO20013384D0 NO20013384D0 (en) 2001-07-06
NO20013384L true NO20013384L (en) 2001-07-06

Family

ID=7893790

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013384A NO20013384L (en) 1999-01-08 2001-07-06 Imidazo [4,5-c] pyridine-4-one derivatives

Country Status (16)

Country Link
EP (1) EP1149099A2 (en)
JP (1) JP2002534429A (en)
KR (1) KR20010086085A (en)
CN (1) CN1333772A (en)
AR (1) AR022220A1 (en)
AU (1) AU3041700A (en)
BR (1) BR9916774A (en)
CA (1) CA2357771A1 (en)
CZ (1) CZ20012407A3 (en)
DE (1) DE19900471A1 (en)
HU (1) HUP0105054A3 (en)
NO (1) NO20013384L (en)
PL (1) PL349341A1 (en)
SK (1) SK9442001A3 (en)
WO (1) WO2000040583A2 (en)
ZA (1) ZA200106454B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1140941T3 (en) 1998-12-23 2005-02-14 Bristol Myers Squibb Pharma Co Nitrogen-containing heterobicyclic compounds as factor Xa inhibitors
ATE373655T1 (en) * 2000-06-23 2007-10-15 Bristol Myers Squibb Pharma Co 1-(HETEROARYL-PHENYL)-CONDENSED PYRAZOLE DERIVATIVES AS FACTOR XA INHIBITORS
EP1414449A4 (en) 2001-05-22 2005-04-06 Bristol Myers Squibb Co Bicyclic inhibitors of factor xa
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
GB0225399D0 (en) * 2002-10-31 2002-12-11 Merck Sharp & Dohme Therapeutic agents
AU2003302238A1 (en) 2002-12-03 2004-06-23 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
EP1706403B9 (en) 2003-12-22 2012-07-25 K.U.Leuven Research & Development Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
WO2006069193A2 (en) 2004-12-21 2006-06-29 Gilead Sciences, Inc. Imidazo[4,5-c]pyridine compound and method of antiviral treatment
BRPI0613045A2 (en) * 2005-07-15 2010-12-14 Hoffmann La Roche heteroaryl fused cyclic amines
WO2007033350A1 (en) 2005-09-14 2007-03-22 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors for treating diabetes
EP1924567B1 (en) 2005-09-16 2012-08-22 Takeda Pharmaceutical Company Limited Process for the preparation of pyrimidinedione derivatives
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP2038275B1 (en) 2006-07-07 2010-01-06 Gilead Sciences, Inc. Novel pyridazine compound and use thereof
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
BR112017002598B1 (en) * 2014-08-12 2022-03-03 Syngenta Participations Ag Pesticide-active heterocyclic derivatives with sulfur-containing substituents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW219935B (en) * 1991-12-25 1994-02-01 Mitsubishi Chemicals Co Ltd
EP1039907A4 (en) * 1997-12-01 2001-09-19 Merck & Co Inc Thrombin inhibitors

Also Published As

Publication number Publication date
CN1333772A (en) 2002-01-30
WO2000040583A3 (en) 2000-09-21
CA2357771A1 (en) 2000-07-13
JP2002534429A (en) 2002-10-15
EP1149099A2 (en) 2001-10-31
WO2000040583A2 (en) 2000-07-13
NO20013384D0 (en) 2001-07-06
DE19900471A1 (en) 2000-07-13
KR20010086085A (en) 2001-09-07
HUP0105054A3 (en) 2002-12-28
PL349341A1 (en) 2002-07-15
CZ20012407A3 (en) 2001-12-12
ZA200106454B (en) 2002-11-06
AR022220A1 (en) 2002-09-04
AU3041700A (en) 2000-07-24
SK9442001A3 (en) 2002-05-09
BR9916774A (en) 2001-10-30
HUP0105054A2 (en) 2002-05-29

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application