NO20012874L - Acylisotiocyanatharpikser og deres anvendelse ved faststoff- bårede synteser av guanidiner - Google Patents

Acylisotiocyanatharpikser og deres anvendelse ved faststoff- bårede synteser av guanidiner

Info

Publication number
NO20012874L
NO20012874L NO20012874A NO20012874A NO20012874L NO 20012874 L NO20012874 L NO 20012874L NO 20012874 A NO20012874 A NO 20012874A NO 20012874 A NO20012874 A NO 20012874A NO 20012874 L NO20012874 L NO 20012874L
Authority
NO
Norway
Prior art keywords
resins
acyl isothiocyanate
product
guanidines
syntheses
Prior art date
Application number
NO20012874A
Other languages
English (en)
Other versions
NO20012874D0 (no
Inventor
Lawrence Joseph Wilson
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO20012874L publication Critical patent/NO20012874L/no
Publication of NO20012874D0 publication Critical patent/NO20012874D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/32—Isothiocyanates having isothiocyanate groups acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Oppfinnelsen vedrører nye acylisotiocyanatharpikser med formelen (I) og fremgangsmåter for fremstilling av disse: (a) utgående fra en fenylkarboksyharpiks som behandles med en hvilken som helst reaktant som omdanner karboksy til acylhaloid, etterfulgt av behandling med tetraalkylammoni- umtiocyanat eller et alkalmetallsalt derav til å gi acyl- isotiocyanatharpiksen. Oppfinnelsen omfatter også en frem- gangsmåte for fremstilling av guanidinforbindelser og rela- terte cykliske forbindelser under anvendelse av en acyliso- tiocyanatharpiks, omfattende de følgende trinn: (b) omsette acylisotiocyanatharpiksen med et primært amin; (c) omsette produktet fra trinn (b) med et svovelaktiver- ende middel og ammonium eller et primært eller sekundært amin; (d) behandle produktet fra trinn (c) med en sterk base eller middel sterk syre for å spalte produktet fra harpiksen til å gi guanidinforbindelsen og/eller den re- laterte cykliske forbindelse.
NO20012874A 1998-12-17 2001-06-11 Acylisotiocyanatharpikser og deres anvendelse ved faststoff- bårede synteser av guanidiner NO20012874D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11275698P 1998-12-17 1998-12-17
PCT/US1999/029771 WO2000035860A2 (en) 1998-12-17 1999-12-15 Acyl isothiocyanate resins and their use in solid-supported synthesis of guanidines

Publications (2)

Publication Number Publication Date
NO20012874L true NO20012874L (no) 2001-06-11
NO20012874D0 NO20012874D0 (no) 2001-06-11

Family

ID=22345679

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012874A NO20012874D0 (no) 1998-12-17 2001-06-11 Acylisotiocyanatharpikser og deres anvendelse ved faststoff- bårede synteser av guanidiner

Country Status (6)

Country Link
US (1) US6420556B1 (no)
JP (1) JP2002532461A (no)
AU (1) AU2185500A (no)
IL (1) IL143360A0 (no)
NO (1) NO20012874D0 (no)
WO (1) WO2000035860A2 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7049333B2 (en) 2002-06-04 2006-05-23 Sanofi-Aventis Deutschland Gmbh Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5041388A (en) * 1989-12-21 1991-08-20 Applied Biosystems, Inc. C-terminal peptide sequencing, activated support and reagent system therefor, and method of producing the activated support

Also Published As

Publication number Publication date
WO2000035860A3 (en) 2000-10-26
JP2002532461A (ja) 2002-10-02
IL143360A0 (en) 2002-04-21
WO2000035860A2 (en) 2000-06-22
US6420556B1 (en) 2002-07-16
NO20012874D0 (no) 2001-06-11
AU2185500A (en) 2000-07-03

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