NO20005570L - Cyklopentanondihydropyridinforbindelser anvendbare som kaliumkanalåpnere - Google Patents

Cyklopentanondihydropyridinforbindelser anvendbare som kaliumkanalåpnere

Info

Publication number
NO20005570L
NO20005570L NO20005570A NO20005570A NO20005570L NO 20005570 L NO20005570 L NO 20005570L NO 20005570 A NO20005570 A NO 20005570A NO 20005570 A NO20005570 A NO 20005570A NO 20005570 L NO20005570 L NO 20005570L
Authority
NO
Norway
Prior art keywords
cyclopentanone
compounds useful
potassium channel
channel openers
dihydropyridine compounds
Prior art date
Application number
NO20005570A
Other languages
English (en)
Other versions
NO20005570D0 (no
Inventor
William A Carroll
Yiyuan Chen
Irene Drizin
James F Kerwin
Jimmie L Moore
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO20005570D0 publication Critical patent/NO20005570D0/no
Publication of NO20005570L publication Critical patent/NO20005570L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO20005570A 1999-03-04 2000-11-03 Cyklopentanondihydropyridinforbindelser anvendbare som kaliumkanalåpnere NO20005570L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/262,441 US6518279B2 (en) 1999-03-04 1999-03-04 Cyclopentanone dihydropyridine compounds useful as potassium channel openers
PCT/US2000/005828 WO2000051986A1 (en) 1999-03-04 2000-03-06 Cyclopentanone dihydropyridine compounds useful as potassium channel openers

Publications (2)

Publication Number Publication Date
NO20005570D0 NO20005570D0 (no) 2000-11-03
NO20005570L true NO20005570L (no) 2000-11-03

Family

ID=22997528

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005570A NO20005570L (no) 1999-03-04 2000-11-03 Cyklopentanondihydropyridinforbindelser anvendbare som kaliumkanalåpnere

Country Status (20)

Country Link
US (1) US6518279B2 (no)
EP (1) EP1075466A1 (no)
JP (1) JP2003517454A (no)
KR (1) KR20010043295A (no)
CN (1) CN1318053A (no)
AR (1) AR028987A1 (no)
AU (1) AU3616800A (no)
BG (1) BG104999A (no)
BR (1) BR0005189A (no)
CA (1) CA2330541A1 (no)
CO (1) CO5150208A1 (no)
HU (1) HUP0102895A3 (no)
IL (1) IL139140A0 (no)
MX (1) MXPA00010790A (no)
NO (1) NO20005570L (no)
PL (1) PL343883A1 (no)
SK (1) SK18152000A3 (no)
TR (1) TR200003202T1 (no)
WO (1) WO2000051986A1 (no)
ZA (1) ZA200005798B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265417B1 (en) 1997-12-18 2001-07-24 Abbott Laboratories Potassium channel openers
US6593335B1 (en) 1997-12-18 2003-07-15 Abbott Laboratories Potassium channel openers
US7074931B2 (en) 2000-08-02 2006-07-11 Astrazeneca Ab Process for asymmetric synthesis of substituted 1,4 -dihydropyridines
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US20030199578A1 (en) * 2002-04-19 2003-10-23 Turner Sean C. Naphthalene amides as potassium channel openers
ATE451359T1 (de) * 2006-02-10 2009-12-15 Janssen Pharmaceutica Nv Neue tricyclische dihydropyrazine als kaliumkanalöffner
CA2752603C (en) 2009-02-18 2016-04-05 Bayer Pharma Aktiengesellschaft Bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives and uses thereof
WO2021253180A1 (en) * 2020-06-15 2021-12-23 Novartis Ag Methyl (r) -2- (fluoromethyl) -5-oxo-4-phenyl-4, 5, 6, 7-tetrahydro-1h-cyclopenta [b] pyridine-3-carboxylate and methyl (r) -2- (fluoromethyl) -5-oxo-4-phenyl-1, 4, 5, 7-tetrahydrofuro [3, 4-b] pyridine-3-carboxylate as cav1.2 activators
US11939316B1 (en) 2023-11-06 2024-03-26 King Faisal University 9-(6-flouro-2-hydroxyouinolin-3-yl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,6,7,9,10-hexhydroacridine-1,8(2h,5h)-dione as an antimicrobial compound
US11970478B1 (en) 2023-11-16 2024-04-30 King Faisal University 9-(2-hydroxyquinolin-3-yl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2003148A1 (de) 1970-01-24 1971-07-29 Bayer Ag Neue 1,4-Dihydropyridinderivate
DE3447170A1 (de) 1984-12-22 1986-07-03 Bayer Ag, 5090 Leverkusen Mischung unterschiedlicher dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
GB8716971D0 (en) 1987-07-17 1987-08-26 Pfizer Ltd Therapeutic agents
GB8907401D0 (en) 1989-04-01 1989-05-17 Pfizer Ltd Therapeutic agents
GB9220570D0 (en) 1991-10-21 1992-11-11 Ici Plc Therapeutic agent
EP0539154B1 (en) 1991-10-21 1997-12-29 Zeneca Limited Acridine-1,8-dione-derivatives as therapeutic agents
GB9318935D0 (en) 1992-10-20 1993-10-27 Zeneca Ltd Heterocyclic derivatives
DE4313690A1 (de) 1993-04-27 1994-11-03 Bayer Ag Kondensierte Chinolyl-dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
IL135985A0 (en) 1997-12-18 2001-05-20 Abbott Lab Potassium channel openers

Also Published As

Publication number Publication date
MXPA00010790A (es) 2002-06-04
SK18152000A3 (sk) 2001-06-11
PL343883A1 (en) 2001-09-10
AU3616800A (en) 2000-09-21
CA2330541A1 (en) 2000-09-08
TR200003202T1 (tr) 2001-08-21
HUP0102895A3 (en) 2002-01-28
AR028987A1 (es) 2003-06-04
JP2003517454A (ja) 2003-05-27
BG104999A (en) 2001-10-31
KR20010043295A (ko) 2001-05-25
BR0005189A (pt) 2001-01-09
NO20005570D0 (no) 2000-11-03
CO5150208A1 (es) 2002-04-29
WO2000051986A1 (en) 2000-09-08
EP1075466A1 (en) 2001-02-14
US6518279B2 (en) 2003-02-11
HUP0102895A2 (hu) 2001-12-28
CN1318053A (zh) 2001-10-17
ZA200005798B (en) 2002-01-18
IL139140A0 (en) 2001-11-25
US20020007065A1 (en) 2002-01-17

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