NO20001487D0 - Expression of genes in hematopoietic stem cells in ischemic states - Google Patents
Expression of genes in hematopoietic stem cells in ischemic statesInfo
- Publication number
- NO20001487D0 NO20001487D0 NO20001487A NO20001487A NO20001487D0 NO 20001487 D0 NO20001487 D0 NO 20001487D0 NO 20001487 A NO20001487 A NO 20001487A NO 20001487 A NO20001487 A NO 20001487A NO 20001487 D0 NO20001487 D0 NO 20001487D0
- Authority
- NO
- Norway
- Prior art keywords
- genes
- expression
- stem cells
- hematopoietic stem
- ischemic states
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
- C12N2740/15052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6045—RNA rev transcr viruses
- C12N2810/6054—Retroviridae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9720216.2A GB9720216D0 (en) | 1997-09-23 | 1997-09-23 | Delivery of therapeutic genes to haematopoietic stem cells |
GBGB9720465.5A GB9720465D0 (en) | 1997-09-25 | 1997-09-25 | Dual-virus vectors |
PCT/GB1998/002885 WO1999015684A2 (en) | 1997-09-23 | 1998-09-23 | Expression of genes in hematopoietic stem cells in hischaemic conditions |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20001487D0 true NO20001487D0 (en) | 2000-03-22 |
NO20001487L NO20001487L (en) | 2000-05-23 |
Family
ID=26312300
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20001487A NO20001487L (en) | 1997-09-23 | 2000-03-22 | Expression of genes in hematopoietic stem cells in ischemic states |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1017838A2 (en) |
JP (1) | JP2001517453A (en) |
KR (1) | KR20010052076A (en) |
CN (1) | CN1303442A (en) |
AU (1) | AU747609B2 (en) |
CA (1) | CA2303663A1 (en) |
GB (1) | GB2345063B (en) |
IL (1) | IL134897A0 (en) |
NO (1) | NO20001487L (en) |
NZ (1) | NZ503318A (en) |
WO (1) | WO1999015684A2 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE420963T1 (en) * | 1998-09-23 | 2009-01-15 | Oxford Biomedica Ltd | POLYNUCLEOTIDE CONSTRUCTS AND USES THEREOF |
US7148035B1 (en) | 1998-11-18 | 2006-12-12 | Oxford Biomedica (Uk) Limited | Polypeptide |
AU766954B2 (en) | 1998-11-18 | 2003-10-30 | Oxford Biomedica (Uk) Limited | Polypeptide |
GB0400443D0 (en) | 2004-01-09 | 2004-02-11 | Oxford Biomedica Ltd | Cascade |
GB9906615D0 (en) * | 1999-03-22 | 1999-05-19 | Oxford Biomedica Ltd | Vector |
WO2001066150A2 (en) * | 2000-03-07 | 2001-09-13 | St. Jude Children's Research Hospital | Highly efficient gene transfer into human repopulating stem cel ls by rd114 pseudotyped retroviral vector particles |
US6849454B2 (en) | 2000-03-07 | 2005-02-01 | St. Jude Children's Research Hospital | Highly efficient gene transfer into human repopulating stem cells by RD114 pseudotyped retroviral vector particles |
GB0009760D0 (en) | 2000-04-19 | 2000-06-07 | Oxford Biomedica Ltd | Method |
GB0024550D0 (en) * | 2000-10-06 | 2000-11-22 | Oxford Biomedica Ltd | |
US6573092B1 (en) | 2000-10-10 | 2003-06-03 | Genvec, Inc. | Method of preparing a eukaryotic viral vector |
GB0203419D0 (en) | 2002-02-13 | 2002-04-03 | Oxford Biomedica Ltd | Peptide |
GB0203420D0 (en) | 2002-02-13 | 2002-04-03 | Oxford Biomedica Ltd | Peptide |
ATE514717T1 (en) | 2002-07-18 | 2011-07-15 | Merus B V | RECOMBINANT PRODUCTION OF ANTIBODIES MIXTURES |
US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
EP2395016A3 (en) | 2003-05-30 | 2012-12-19 | Merus B.V. | Design and use of paired variable regions of specific binding molecules |
JP4572320B2 (en) * | 2004-02-23 | 2010-11-04 | 財団法人大阪産業振興機構 | Recombinant human cell and method for evaluating at least one of induction of drug metabolizing enzyme and drug metabolism using the recombinant human cell |
EP2277918B1 (en) | 2005-05-13 | 2012-11-14 | Oxford BioMedica (UK) Limited | Mhc class I and II peptide antigens derived from tumour antigen 5t4 |
JP2009537137A (en) | 2006-05-17 | 2009-10-29 | コグネート セラピューティクス,インコーポレーテッド | Isolation and purification of hematopoietic stem cells from lipoaspirate after liposuction |
US9248181B2 (en) | 2012-04-20 | 2016-02-02 | Merus B.V. | Methods and means for the production of Ig-like molecules |
US11072803B2 (en) | 2015-12-22 | 2021-07-27 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Hybrid dual recombinant AAV vector systems for gene therapy |
CN113699146A (en) * | 2020-05-22 | 2021-11-26 | 深圳市深研生物科技有限公司 | Promoter element, retroviral genome transcription cassette comprising the same, and vector |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06509578A (en) * | 1991-07-26 | 1994-10-27 | ユニバーシティ・オブ・ロチェスター | Cancer treatment using malignant cells |
FR2709309B1 (en) * | 1993-08-25 | 1995-11-10 | Centre Nat Rech Scient | Cellular compositions, preparation and therapeutic uses. |
GB9402857D0 (en) * | 1994-02-15 | 1994-04-06 | Isis Innovation | Targeting gene therapy |
WO1995029704A1 (en) * | 1994-04-28 | 1995-11-09 | Scott Freeman | Cell lines obtained by in vivo migration and by fusion with autoimmune cells |
US5834306A (en) * | 1994-12-23 | 1998-11-10 | Sri International | Tissue specific hypoxia regulated therapeutic constructs |
GB2332434B (en) * | 1996-10-09 | 2001-04-04 | Oxford Biomedica Ltd | Mononuclear phagocytes in therapeutic drug delivery |
-
1998
- 1998-09-23 CA CA002303663A patent/CA2303663A1/en not_active Abandoned
- 1998-09-23 AU AU93562/98A patent/AU747609B2/en not_active Ceased
- 1998-09-23 EP EP98946556A patent/EP1017838A2/en not_active Withdrawn
- 1998-09-23 IL IL13489798A patent/IL134897A0/en unknown
- 1998-09-23 JP JP2000512973A patent/JP2001517453A/en active Pending
- 1998-09-23 GB GB0006993A patent/GB2345063B/en not_active Expired - Fee Related
- 1998-09-23 CN CN98811427A patent/CN1303442A/en active Pending
- 1998-09-23 NZ NZ503318A patent/NZ503318A/en unknown
- 1998-09-23 WO PCT/GB1998/002885 patent/WO1999015684A2/en not_active Application Discontinuation
- 1998-09-23 KR KR1020007003066A patent/KR20010052076A/en not_active Application Discontinuation
-
2000
- 2000-03-22 NO NO20001487A patent/NO20001487L/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2303663A1 (en) | 1999-04-01 |
WO1999015684A2 (en) | 1999-04-01 |
NO20001487L (en) | 2000-05-23 |
IL134897A0 (en) | 2001-05-20 |
WO1999015684A8 (en) | 1999-08-12 |
GB2345063A (en) | 2000-06-28 |
KR20010052076A (en) | 2001-06-25 |
AU747609B2 (en) | 2002-05-16 |
NZ503318A (en) | 2001-11-30 |
CN1303442A (en) | 2001-07-11 |
WO1999015684A9 (en) | 1999-09-16 |
GB0006993D0 (en) | 2000-05-10 |
AU9356298A (en) | 1999-04-12 |
WO1999015684A3 (en) | 1999-06-10 |
EP1017838A2 (en) | 2000-07-12 |
JP2001517453A (en) | 2001-10-09 |
GB2345063B (en) | 2002-07-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20001487L (en) | Expression of genes in hematopoietic stem cells in ischemic states | |
NO20001244D0 (en) | Method of delivering genes to antigen presenting cells in the skin | |
NO975748D0 (en) | Chromosomal expression of heterologous genes in bacterial cells | |
DE69836191D1 (en) | Fuel cell and bipolar partition wall for it | |
NO993595L (en) | Transfer of ATM cells | |
DE69810270T2 (en) | DIFFERENTIAL FLASH STORAGE CELL AND OPERATING METHOD THEREFOR | |
ID19961A (en) | THIN TYPE OF CELL | |
DK199901519A (en) | In the form of small molecules are inhibitors of rotamase enzyme activity | |
DK199901518A (en) | In the form of small molecules are inhibitors of rotamase enzyme activity | |
DE69727581D1 (en) | RAM memory cell with low power consumption | |
DE69924484D1 (en) | DSRNA-CONDITIONING REGULATION OF GENE EXPRESSION IN PLANTS | |
DE69838594D1 (en) | Multi-axis load cell | |
EE9900572A (en) | Structure of load distribution in computer networks | |
AU9200398A (en) | A process to study changes in gene expression in granulocytic cells | |
DE69535352D1 (en) | EXPRESSION OF BAZILLUS THURINGIENSIS CRY PROTEINS IN PLANT PLASTIDES | |
NO983775D0 (en) | Regulation of gene expression in eukaryotes | |
NO20011459D0 (en) | Genes in the biosynthesis pathway of 1-deoxy-D-xylulose | |
DE69727492D1 (en) | GENETIC MODIFICATION OF HEMATOPOIETIC REPOPULATION OF STEM CELLS IN PRIMATES | |
ATE327337T1 (en) | IMPROVEMENTS IN GENE EXPRESSION SPECIFICITY | |
AU4214799A (en) | Expansion of hematopoietic stem cells transduced with mdr-1 and methods of use thereof | |
NO20015168D0 (en) | A synthetic gene for expression of a retrovirus protein with random type of activity in eukaryotic cells | |
DE59903684D1 (en) | DUAL-PORT STORAGE CELL | |
AU9732098A (en) | Hematopoietic stem cells | |
FI972336A0 (en) | Increased biosynthesis of biotin in plant cells | |
DE59812838D1 (en) | STORAGE STABLE BLEACH ACTIVATOR GRANULATE |