NO179891B - Oral and dental care - Google Patents
Oral and dental care Download PDFInfo
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- NO179891B NO179891B NO912267A NO912267A NO179891B NO 179891 B NO179891 B NO 179891B NO 912267 A NO912267 A NO 912267A NO 912267 A NO912267 A NO 912267A NO 179891 B NO179891 B NO 179891B
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- binder
- oral
- foil
- dental care
- mixture
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- 239000011888 foil Substances 0.000 claims abstract description 23
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 21
- 239000000203 mixture Substances 0.000 claims abstract description 18
- 239000011230 binding agent Substances 0.000 claims abstract description 15
- 239000000126 substance Substances 0.000 claims abstract description 8
- 239000000654 additive Substances 0.000 claims abstract description 7
- 239000004094 surface-active agent Substances 0.000 claims abstract description 6
- 238000005498 polishing Methods 0.000 claims abstract description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 15
- 239000011248 coating agent Substances 0.000 claims description 5
- 238000000576 coating method Methods 0.000 claims description 5
- 235000011187 glycerol Nutrition 0.000 claims description 4
- 108010010803 Gelatin Proteins 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- 229920000159 gelatin Polymers 0.000 claims description 3
- 235000019322 gelatine Nutrition 0.000 claims description 3
- 235000011852 gelatine desserts Nutrition 0.000 claims description 3
- 239000000123 paper Substances 0.000 claims description 3
- 239000000600 sorbitol Substances 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- 239000000025 natural resin Substances 0.000 claims description 2
- 229920003002 synthetic resin Polymers 0.000 claims description 2
- 239000000057 synthetic resin Substances 0.000 claims description 2
- 238000000926 separation method Methods 0.000 claims 3
- 230000000996 additive effect Effects 0.000 claims 1
- 239000012876 carrier material Substances 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 abstract description 2
- 239000000606 toothpaste Substances 0.000 description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 8
- 238000004140 cleaning Methods 0.000 description 5
- 229940034610 toothpaste Drugs 0.000 description 5
- 210000000214 mouth Anatomy 0.000 description 4
- 239000000377 silicon dioxide Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 2
- 239000006072 paste Substances 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 238000004080 punching Methods 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- 235000010356 sorbitol Nutrition 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- 108010011485 Aspartame Proteins 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 208000006558 Dental Calculus Diseases 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 239000003082 abrasive agent Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000010617 anise oil Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 239000000605 aspartame Substances 0.000 description 1
- 235000010357 aspartame Nutrition 0.000 description 1
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 1
- 229960003438 aspartame Drugs 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 239000010630 cinnamon oil Substances 0.000 description 1
- 239000010634 clove oil Substances 0.000 description 1
- 229940109275 cyclamate Drugs 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 239000000551 dentifrice Substances 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 150000002222 fluorine compounds Chemical class 0.000 description 1
- 125000001153 fluoro group Chemical class F* 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052500 inorganic mineral Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 1
- 239000001683 mentha spicata herb oil Substances 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000011707 mineral Chemical class 0.000 description 1
- -1 monoglyceride sulfates Chemical class 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 235000019477 peppermint oil Nutrition 0.000 description 1
- 235000021395 porridge Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 229940075560 sodium lauryl sulfoacetate Drugs 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 description 1
- 235000019721 spearmint oil Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical class [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
- Dental Preparations (AREA)
Abstract
Description
Foreliggende oppfinnelse vedrører et munn- og tannpleiemiddel på basis av tensider, poleringsmidler, aromastoffer samt ytterligere vanlige tilsatsstoffer. The present invention relates to an oral and dental care product based on surfactants, polishing agents, flavoring substances and further common additives.
Tannpleiemidler har i mange år vært fremstilt som pastaer, såkalte tannpastaer. Derved er det vesentlige utgangsstoffet et slamkritt som bearbeides med vann, glyserol, vaskeaktive stoffer og fortykningsmidler til en pasta og fylles i tuber eller avgivelsesinnretninger. Tannpasta har erobret markedet mens andre tannpleiemidler som dråper, tannsåper og -pulvere eller granulater knapt spiller noen rolle. Med midlene skal bakterielle tannbelegg fjernes, det skal drives karies-profylakse, videre skal rensingen av tennene gjennomføres skånende og vesentlig understøttet av børstebehandlingen, og munnhulen skal renses grundig og gjøres behagelig frisk. Tooth care products have for many years been produced as pastes, so-called toothpastes. Thereby, the essential starting material is a mud chalk that is processed with water, glycerol, detergent active substances and thickeners into a paste and filled in tubes or dispensing devices. Toothpaste has conquered the market, while other dental care products such as drops, dental soaps and powders or granules hardly play any role. With the agents, bacterial dental plaque must be removed, caries prophylaxis must be carried out, the cleaning of the teeth must also be carried out gently and significantly supported by the brushing treatment, and the oral cavity must be thoroughly cleaned and made pleasantly fresh.
I den senere tid har bildet av tannpastaene ikke endret seg vesentlig, selv om sammensetningene er forandret i mange henseende. Anvendelsen av en heller grov krittform for mekanisk rensing av tennene viker mer og mer for moderne, finere poleringsmidler på basis av aluminiumoksyd eller silisiumdioksyd (kiselgeler). Ved siden av tensider finnes strukturdannende komponenter og utsøkte smakskorrigerende midler anvendelse. Ofte tilsettes virksomme stoffer som spesielt forskjellige fluorderivater eller mineralsalter. Volumene har delvis kunnet reduseres; ganske sikkert har innføringen og den generelle anvendelsen av elektriske tannbørster her hatt en sterk innvirkning. In recent times, the image of toothpastes has not changed significantly, although the compositions have changed in many respects. The use of a rather coarse form of chalk for mechanical cleaning of the teeth gives way more and more to modern, finer polishing agents based on aluminum oxide or silicon dioxide (silica gels). Next to surfactants, structure-forming components and exquisite flavor correcting agents are used. Often, active substances such as various fluorine derivatives or mineral salts are added. The volumes have partially been able to be reduced; certainly the introduction and general use of electric toothbrushes has had a strong impact here.
Håndteringen av tannpastaer er imidlertid forbundet med en rekke ulemper. Fordi doseringen fra enkle tuber byr på vanskeligheter har man i senere tid utviklet tannpastaav-givelsesinnretninger, som i ethvert tilfelle avgir en på forhånd bestemt mengde tannpasta. Disse avgivelsesinn-retningene er imidlertid forholdsvis store og følgelig lite egnede for å ha med på reiser. Tuber er trykkfølsomme og følgelig heller ikke ideelle for reiser. Såvel i avgivelsesinnretninger som i tuber kan tannpastaen tørke ut ved lengre bruksavbrudd, slik at den påbegynte beholderen så må kastes. Videre lar hverken tuber eller avgivelsesinnretninger seg tømme fullstendig. Etter bruk blir beholderne fremstilt av metall eller plast tilbake og forårsaker miljøproblemer. However, the handling of toothpastes is associated with a number of disadvantages. Because dosing from simple tubes presents difficulties, toothpaste dispensing devices have recently been developed, which in any case dispense a pre-determined amount of toothpaste. However, these dispensing devices are relatively large and consequently not suitable for taking with you on trips. Tubes are pressure sensitive and therefore also not ideal for travel. In dispensing devices as well as in tubes, the toothpaste can dry out during prolonged interruptions of use, so that the started container must then be thrown away. Furthermore, neither tubes nor delivery devices allow themselves to be completely emptied. After use, the containers made of metal or plastic are returned and cause environmental problems.
Til grunn for oppfinnelsen ligger den oppgaven å utvikle en ny utlevering- og doseringsform for munn- og tannpleiemiddel som ikke oppviser de ovenfor angitte ulempene. Spesielt skal en nøyaktig dosering for den enkelte tannrensingen mulig-gjøres, og det skal sikres at middelet kan forbrukes fullstendig uten at rester blir tilbake i pakningen. The invention is based on the task of developing a new delivery and dosage form for oral and dental care which does not exhibit the above-mentioned disadvantages. In particular, an accurate dosage for the individual teeth cleaning must be made possible, and it must be ensured that the agent can be consumed completely without any residue remaining in the package.
Munn- og tannpleiemiddelet ifølge oppfinnelsen på basis av tensider, poleringsmidler, aromastoffer samt ytterligere vanlige tilsatsstoffer, er kjennetegnet ved at virke- og tilsatsstoffene er innarbeidet i et bindemiddel eller en bindemiddelblanding som består av vannoppløselige eller -svellbare, fysiologisk godtagbare foliedannere, og at denne blandingen er bearbeidet til en folie, hvorved den derved dannede folien er foroppdelt i doseringsenheter. The oral and dental care product according to the invention, based on surfactants, polishing agents, flavoring substances and further common additives, is characterized by the fact that the active substances and additives are incorporated into a binder or a binder mixture consisting of water-soluble or -swellable, physiologically acceptable foil formers, and that this the mixture is processed into a foil, whereby the resulting foil is pre-divided into dosage units.
Som bestanddeler av munn- og tannpleiemiddelet kommer de komponentene på tale som vanligvis finner anvendelse for fremstilling av tannpastaer, hvorved naturlige råstoffer er spesielt foretrukket. Viktig er det dessuten at alle bestanddelene er fullstendig ugiftige og fysiologisk godtagbare, hvilket naturligvis også gjelder for den anvendte foliedanneren. Som vesentlige bestanddeler av tannpleie-midlene skal nevnes: - slipemiddel som kritt (kalsiumkarbonat), kalsium- og natriumfosfåter, aluminiumoksyd eller silisiumdioksyd, spesielt kiselgeler - tensider (skummemidler) som natriumlaurylsulfat, natrium-laurylsulfoacetat, sarkosider, monoglyseridsulfater og andre As components of the oral and dental care agent, the components that are usually used for the production of toothpastes are mentioned, whereby natural raw materials are particularly preferred. It is also important that all the components are completely non-toxic and physiologically acceptable, which of course also applies to the foil former used. The following should be mentioned as essential components of the dental care products: - abrasives such as chalk (calcium carbonate), calcium and sodium phosphates, aluminum oxide or silicon dioxide, especially silica gels - surfactants (foaming agents) such as sodium lauryl sulfate, sodium lauryl sulfoacetate, sarcosides, monoglyceride sulfates and others
aromastoffer som peppermynteolje, krusemynteolje, aroma substances such as peppermint oil, spearmint oil,
anisolje, kanelolje, nellikolje, mentol og lignende anise oil, cinnamon oil, clove oil, menthol and the like
søtningsstoffer som sakkarin, cyklamat, aspartam og sweeteners such as saccharin, cyclamate, aspartame and
1ignende. 1igning.
De i tannpastaer vanligvis tilstedeværende flytende komponentene som glyserol, propylenglykol eller sorbitsirup må for midlene i folieform ifølge oppfinnelsen ikke tilsettes i de vanlige mengdene, idet den for tuber eller avgivelsesinnretninger nødvendige plastisiteten i dette tilfellet ikke spiller noen rolle. Ytterligere vanlige tilsatser som fluorforbindelser, middel mot tannstendannelse, antibakteri-elle virkestoffer og lignende, som vanligvis finner anvendelse i munn- og tannpleiemidler, kan også anvendes ifølge oppf innelsen. The liquid components usually present in toothpastes, such as glycerol, propylene glycol or sorbitol syrup, must not be added in the usual quantities for the agents in foil form according to the invention, as the plasticity required for tubes or dispensing devices in this case does not play any role. Further common additives such as fluorine compounds, agents against tartar formation, antibacterial agents and the like, which usually find use in oral and dental care products, can also be used according to the invention.
Som vannoppløselige, henholdsvis —svellbare, foliedannere egner seg fremfor alt stivelser, gelatiner, glyserol og/eller sorbit, samt videre naturlige eller syntetiske harpikser og gummier. Følgende rammesammensetning har vist seg hen-siktsmessig : Starches, gelatins, glycerol and/or sorbitol, as well as further natural or synthetic resins and gums are suitable as water-soluble or swellable foil formers. The following frame composition has proven to be appropriate:
I denne grunnmassen oppløses henholdsvis dispergeres bestanddelene av munn- og tannpleiemiddelet, for å oppnå en jevn fordeling av stoffene. Den derved oppnådde blandingen kan på forskjellig måte bearbeides til et folieformig munn-og tannpleiemiddel: In this base mass, the components of the oral and dental care agent are dissolved or dispersed, in order to achieve an even distribution of the substances. The resulting mixture can be processed in different ways into a foil-shaped oral and dental care product:
a) Det er mulig å bearbeide massen direkte til en folie, som generelt oppviser en tykkelse mellom 0,1 og 3 mm. Ved hjelp av skalbruddstedet ved stansing eller perforering kan denne folien oppdeles i doseringsenheter, hvorved båndbredden og —lengden fortrinnsvis tilnærmet skal tilsvare tannbørstestørrelsen, det vil si den fra den frie børsteenden dannede flaten av børsteblokken, eller lengdetverrsnittsflaten av bøsteblokken i børsteplanet. b) Alternativt kan massen påføres på en bærerfolie hvis sammensetning tilsvarer den for bindemiddelet av massen, a) It is possible to process the mass directly into a foil, which generally has a thickness between 0.1 and 3 mm. With the aid of the shell breaking point during punching or perforation, this foil can be divided into dosage units, whereby the strip width and length should preferably correspond approximately to the toothbrush size, i.e. the surface of the brush block formed from the free brush end, or the longitudinal cross-sectional surface of the brush block in the brush plane. b) Alternatively, the mass can be applied to a carrier foil whose composition corresponds to that of the binder of the mass,
slik dette beskrives detaljert i EP-OS 219 762. Også de på denne måten oppnådde foliene kan være foroppdelt som angitt ovenfor. as this is described in detail in EP-OS 219 762. The foils obtained in this way can also be pre-divided as indicated above.
c) Det er videre mulig å påføre massen på slippfolie eller et slipp-papir, som kjent fra DE-PS 36 30 603. I dette c) It is also possible to apply the mass to release foil or a release paper, as known from DE-PS 36 30 603. In this
tilfelle foroppdeles besjiktningen i enkelte avsnitt av den ovenfor angitte størrelsen, som kan trekkes av på tilsvarende måte som klebeetiketter fra bærerfolien før bruk. in this case, the coating is pre-divided into individual sections of the size indicated above, which can be peeled off in a similar way to adhesive labels from the carrier foil before use.
I alle tilfeller oppnår man en administrerings- og doseringsform hvis anvendelse er spesielt enkel, idet mengden som i ethvert tilfelle skal anvendes er gitt på forhånd. En dose adskilles, henholdsvis trekkes av, i form av et foliestykke og legges på den fuktede tannbørsten, henholdsvis mellom børstene, hvor den hefter på grunn av fuktighetsberøringen og sveller opp. Ved innføringen i munnhulen og i forbindelse med spyttet og den intense tannbørstebevegelsen oppløses båndet, slik at innholdsstoffene utfolder sin fulle virkning. Etter anvendelsen og den etterfølgende munnspylingen med vann forblir ingen rester i munnen. In all cases, an administration and dosage form is obtained whose use is particularly simple, as the amount to be used in each case is given in advance. A dose is separated, or pulled off, in the form of a piece of foil and placed on the moistened toothbrush, or between the brushes, where it adheres due to the contact with moisture and swells up. When introduced into the oral cavity and in connection with the saliva and the intense toothbrush movement, the band dissolves, so that the ingredients unfold their full effect. After the application and the subsequent rinsing with water, no residue remains in the mouth.
Om ønsket kan foliene være påtrykket, preget eller stanset på forskjellig måte, hvorved det eksempelvis for barn også er mulig med billedlige angivelser. Åpningen og lukkingen av tuben bortfaller, ingen tannpasta sløses bort og utleverings-formen ifølge oppfinnelsen lar seg også spesielt lett anvende på reise, idet den er lett, det foreligger ingen fare for utflyting og den tar ytterst lite plass. Forpakningen kan gjøres miljøvennlig i pappesker uten anvendelse av metaller eller kunststoff. If desired, the foils can be imprinted, embossed or punched in different ways, whereby it is also possible for children, for example, with pictorial indications. The opening and closing of the tube is omitted, no toothpaste is wasted and the dispensing form according to the invention can also be particularly easily used when travelling, as it is light, there is no risk of leakage and it takes up very little space. The packaging can be made environmentally friendly in cardboard boxes without the use of metals or plastics.
Middelet ifølge oppfinnelsen egner seg ikke bare for tannpleie i munnen, men ved egnet sammensetning også for rensing og pleie av kunstige tenner og gebisser. For dette siste anvendelsesformålet er en flere gangers besjikting spesielt gunstig, hvorved de rensende, desinfiserende og sure komponenter befinner seg i ett sjikt, mens det, eventuelt adskilt ved et også vannoppløselig sperresjikt, i et andre sjikt befinner seg CO2- henholdsvis C^-avgivende stoffer. The agent according to the invention is not only suitable for dental care in the mouth, but with a suitable composition also for cleaning and caring for artificial teeth and dentures. For this last purpose of application, a layering several times is particularly advantageous, whereby the cleaning, disinfecting and acidic components are located in one layer, while, optionally separated by a barrier layer that is also water-soluble, in a second layer there are CO2- or C^-emitting substances.
Eksempel Example
Et tannpleiemiddel ifølge oppfinnelsen har følgende sammensetning: A dentifrice according to the invention has the following composition:
Med den nødvendige mengde vann fremstilles en grøt som bearbeides til en folie som er ca. 0,5 mm tykk. Ved perforering oppdeles folien i avsnitt på 8 x 35 mm. With the required amount of water, a porridge is prepared which is processed into a foil that is approx. 0.5 mm thick. When perforating, the foil is divided into sections of 8 x 35 mm.
Eventuelt kan massen også som besjiktning påføres på et slipp-papir som bærer og foroppdeles i avsnitt av angitt størrelse ved stansing. Optionally, the mass can also be applied as a coating to a release paper that supports and is pre-divided into sections of the specified size by punching.
Claims (6)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3934416 | 1989-10-14 | ||
| PCT/EP1990/001936 WO1991005540A1 (en) | 1989-10-14 | 1990-10-15 | Oral and dental hygiene preparation |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO912267D0 NO912267D0 (en) | 1991-06-12 |
| NO912267L NO912267L (en) | 1991-06-12 |
| NO179891B true NO179891B (en) | 1996-09-30 |
| NO179891C NO179891C (en) | 1997-01-08 |
Family
ID=6391526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO912267A NO179891C (en) | 1989-10-14 | 1991-06-12 | Oral and dental care |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0452446B1 (en) |
| JP (1) | JP3043804B2 (en) |
| AT (1) | ATE99165T1 (en) |
| AU (1) | AU627950B2 (en) |
| BR (1) | BR9006965A (en) |
| CA (1) | CA2044172A1 (en) |
| DE (1) | DE59004042D1 (en) |
| DK (1) | DK0452446T3 (en) |
| ES (1) | ES2062562T3 (en) |
| FI (1) | FI95346C (en) |
| NO (1) | NO179891C (en) |
| WO (1) | WO1991005540A1 (en) |
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|---|---|---|---|---|
| DE19646392A1 (en) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Preparation for use in the oral cavity with a layer containing pressure-sensitive adhesive, pharmaceuticals or cosmetics for dosed delivery |
| DE19652257A1 (en) | 1996-12-16 | 1998-06-18 | Lohmann Therapie Syst Lts | Individually dosed, film-like dosage form that quickly disintegrates on contact with liquid and contains active ingredients and especially flavorings |
| US6231957B1 (en) | 1999-05-06 | 2001-05-15 | Horst G. Zerbe | Rapidly disintegrating flavor wafer for flavor enrichment |
| US6660292B2 (en) | 2001-06-19 | 2003-12-09 | Hf Flavoring Technology Llp | Rapidly disintegrating flavored film for precooked foods |
| US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
| US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
| US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
| US7425292B2 (en) | 2001-10-12 | 2008-09-16 | Monosol Rx, Llc | Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom |
| US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
| US7666337B2 (en) | 2002-04-11 | 2010-02-23 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
| US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US7910641B2 (en) | 2001-10-12 | 2011-03-22 | Monosol Rx, Llc | PH modulated films for delivery of actives |
| US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
| US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US8663687B2 (en) | 2001-10-12 | 2014-03-04 | Monosol Rx, Llc | Film compositions for delivery of actives |
| US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
| US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
| US8017150B2 (en) | 2002-04-11 | 2011-09-13 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
| FR2840221B1 (en) * | 2002-06-04 | 2006-01-13 | Backert Marie Elisabeth Cuine | POLYMERIC FILM CONTAINING "ACTIVE" TO BE RELEASED IN A LIQUID |
| JP2009514597A (en) | 2005-11-04 | 2009-04-09 | ライフサイエンス・プラス・インコーポレイテッド | Bioabsorbable hemostatic gauze |
| FR2916635B1 (en) * | 2007-05-30 | 2009-08-07 | Backert Marie Elisabeth Cuine | SOLID FORMULATIONS FOR ADMINISTRATION, PARENTLY PARENTAL, OF ACTI (S), IN THE FORM OF A FILM INTENDED TO BE DISSOLVED AND / OR DISPERSED IN A LIQUID PRODUCT |
| US8765155B2 (en) * | 2007-08-30 | 2014-07-01 | Colgate-Palmolive Company | Oral care strip or tape and methods of use and manufacture thereof |
| DE102008023345B4 (en) | 2008-05-13 | 2014-12-04 | Lts Lohmann Therapie-Systeme Ag | Film-like preparation with oily substances for oral administration |
| US9265779B2 (en) | 2008-05-13 | 2016-02-23 | Lts Lohmann Therapie-Systeme Ag | Method of using a film-shaped preparation comprising oily substances for oral administration |
| US8475832B2 (en) | 2009-08-07 | 2013-07-02 | Rb Pharmaceuticals Limited | Sublingual and buccal film compositions |
| US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
| US20110136815A1 (en) | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| ES2569339T3 (en) | 2010-06-10 | 2016-05-10 | Midatech Ltd. | Nanoparticle Film Management Systems |
| US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
| JPWO2013108384A1 (en) * | 2012-01-19 | 2015-05-11 | ツキオカフィルム製薬株式会社 | Film-like dentifrice |
| WO2013108384A1 (en) * | 2012-01-19 | 2013-07-25 | 株式会社ツキオカ | Film-shaped dentifrices |
| US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
| JP2019519487A (en) | 2016-05-05 | 2019-07-11 | アクエスティブ セラピューティクス インコーポレイテッド | Delivery enhancing epinephrine composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1476057A (en) * | 1975-03-20 | 1977-06-10 | Unicliffe Ltd | Throat pastilles |
| GB8421226D0 (en) * | 1984-08-21 | 1984-09-26 | Int Conferences Ab | Tooth cleaning tablet |
| EP0219762B1 (en) * | 1985-10-09 | 1990-12-27 | Desitin Arzneimittel GmbH | Process for the preparation of an administration and dosage for drugs, reagents or other active substances |
| US4765984A (en) * | 1986-01-22 | 1988-08-23 | Colgate-Palmolive Company | Stable single unit dose oral product |
| DE3630603A1 (en) * | 1986-09-09 | 1988-03-10 | Desitin Arzneimittel Gmbh | PHARMACEUTICAL AND DOSAGE FORM FOR MEDICINAL ACTIVE SUBSTANCES, REAGENTS OR THE LIKE, AND METHOD FOR THE PRODUCTION THEREOF |
-
1990
- 1990-10-15 WO PCT/EP1990/001936 patent/WO1991005540A1/en active IP Right Grant
- 1990-10-15 CA CA002044172A patent/CA2044172A1/en not_active Abandoned
- 1990-10-15 DE DE90915758T patent/DE59004042D1/en not_active Expired - Fee Related
- 1990-10-15 AT AT90915758T patent/ATE99165T1/en not_active IP Right Cessation
- 1990-10-15 DK DK90915758.8T patent/DK0452446T3/en active
- 1990-10-15 EP EP90915758A patent/EP0452446B1/en not_active Expired - Lifetime
- 1990-10-15 BR BR909006965A patent/BR9006965A/en not_active IP Right Cessation
- 1990-10-15 JP JP2514619A patent/JP3043804B2/en not_active Expired - Fee Related
- 1990-10-15 ES ES90915758T patent/ES2062562T3/en not_active Expired - Lifetime
- 1990-10-15 AU AU66094/90A patent/AU627950B2/en not_active Ceased
-
1991
- 1991-06-12 NO NO912267A patent/NO179891C/en not_active IP Right Cessation
- 1991-06-13 FI FI912849A patent/FI95346C/en active
Also Published As
| Publication number | Publication date |
|---|---|
| NO179891C (en) | 1997-01-08 |
| NO912267D0 (en) | 1991-06-12 |
| NO912267L (en) | 1991-06-12 |
| FI95346C (en) | 1996-01-25 |
| AU6609490A (en) | 1991-05-16 |
| AU627950B2 (en) | 1992-09-03 |
| JPH04502332A (en) | 1992-04-23 |
| CA2044172A1 (en) | 1991-04-15 |
| DK0452446T3 (en) | 1994-01-24 |
| BR9006965A (en) | 1991-11-12 |
| EP0452446A1 (en) | 1991-10-23 |
| JP3043804B2 (en) | 2000-05-22 |
| FI95346B (en) | 1995-10-13 |
| WO1991005540A1 (en) | 1991-05-02 |
| FI912849A0 (en) | 1991-06-13 |
| DE59004042D1 (en) | 1994-02-10 |
| ES2062562T3 (en) | 1994-12-16 |
| EP0452446B1 (en) | 1993-12-29 |
| ATE99165T1 (en) | 1994-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |