NO179583C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indoler - Google Patents
Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indolerInfo
- Publication number
- NO179583C NO179583C NO913140A NO913140A NO179583C NO 179583 C NO179583 C NO 179583C NO 913140 A NO913140 A NO 913140A NO 913140 A NO913140 A NO 913140A NO 179583 C NO179583 C NO 179583C
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen
- loweralkyl
- pyridinylalkyl
- indoles
- preparation
- Prior art date
Links
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000006949 cholinergic function Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 230000007074 memory dysfunction Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- -1 nitro, amino Chemical group 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Display Devices Of Pinball Game Machines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56657590A | 1990-08-13 | 1990-08-13 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO913140D0 NO913140D0 (no) | 1991-08-12 |
| NO913140L NO913140L (no) | 1992-02-14 |
| NO179583B NO179583B (no) | 1996-07-29 |
| NO179583C true NO179583C (no) | 1996-11-06 |
Family
ID=24263468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO913140A NO179583C (no) | 1990-08-13 | 1991-08-12 | Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indoler |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0471296B1 (cs) |
| JP (1) | JP3057828B2 (cs) |
| KR (1) | KR100223133B1 (cs) |
| AT (1) | ATE130002T1 (cs) |
| AU (1) | AU637249B2 (cs) |
| CA (1) | CA2048980C (cs) |
| CS (1) | CS249191A3 (cs) |
| DE (1) | DE69114404T2 (cs) |
| DK (1) | DK0471296T3 (cs) |
| ES (1) | ES2079530T3 (cs) |
| FI (1) | FI103341B (cs) |
| GR (1) | GR3018187T3 (cs) |
| HU (1) | HUT58722A (cs) |
| IE (1) | IE70596B1 (cs) |
| IL (1) | IL99168A (cs) |
| MX (1) | MX9100638A (cs) |
| NO (1) | NO179583C (cs) |
| NZ (2) | NZ260632A (cs) |
| PL (1) | PL291408A1 (cs) |
| ZA (1) | ZA916341B (cs) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5068234A (en) * | 1990-02-26 | 1991-11-26 | Sterling Drug Inc. | 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles |
| DE69114210T2 (de) * | 1990-08-13 | 1996-05-02 | Hoechst Roussel Pharma | Carbamoyl-1-(pyridinylalkyl)-1H-indole, -indoline und verwandte Verbindungen. |
| FR2674522B1 (fr) * | 1991-03-26 | 1993-07-16 | Lipha | Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant. |
| WO2003087087A2 (en) * | 2002-04-09 | 2003-10-23 | Astex Technology Limited | Heterocyclic compounds and their use as modulators of p38 map kinase |
-
1991
- 1991-08-08 AT AT91113333T patent/ATE130002T1/de not_active IP Right Cessation
- 1991-08-08 DE DE69114404T patent/DE69114404T2/de not_active Expired - Fee Related
- 1991-08-08 EP EP91113333A patent/EP0471296B1/en not_active Expired - Lifetime
- 1991-08-08 DK DK91113333.8T patent/DK0471296T3/da active
- 1991-08-08 ES ES91113333T patent/ES2079530T3/es not_active Expired - Lifetime
- 1991-08-09 NZ NZ260632A patent/NZ260632A/en unknown
- 1991-08-09 FI FI913799A patent/FI103341B/fi active
- 1991-08-09 NZ NZ239328A patent/NZ239328A/en unknown
- 1991-08-12 HU HU912674A patent/HUT58722A/hu unknown
- 1991-08-12 CA CA002048980A patent/CA2048980C/en not_active Expired - Fee Related
- 1991-08-12 IE IE285091A patent/IE70596B1/en not_active IP Right Cessation
- 1991-08-12 IL IL9916891A patent/IL99168A/en unknown
- 1991-08-12 CS CS912491A patent/CS249191A3/cs unknown
- 1991-08-12 KR KR1019910013849A patent/KR100223133B1/ko not_active Expired - Fee Related
- 1991-08-12 PL PL29140891A patent/PL291408A1/xx unknown
- 1991-08-12 ZA ZA916341A patent/ZA916341B/xx unknown
- 1991-08-12 JP JP3201711A patent/JP3057828B2/ja not_active Expired - Fee Related
- 1991-08-12 AU AU81767/91A patent/AU637249B2/en not_active Ceased
- 1991-08-12 MX MX9100638A patent/MX9100638A/es not_active IP Right Cessation
- 1991-08-12 NO NO913140A patent/NO179583C/no unknown
-
1995
- 1995-11-22 GR GR950403313T patent/GR3018187T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE130002T1 (de) | 1995-11-15 |
| JPH05132481A (ja) | 1993-05-28 |
| EP0471296A1 (en) | 1992-02-19 |
| ZA916341B (en) | 1992-04-29 |
| FI913799A7 (fi) | 1992-02-14 |
| FI103341B1 (fi) | 1999-06-15 |
| PL291408A1 (en) | 1992-12-28 |
| KR920004379A (ko) | 1992-03-27 |
| AU8176791A (en) | 1992-02-20 |
| FI103341B (fi) | 1999-06-15 |
| DK0471296T3 (da) | 1996-03-11 |
| DE69114404T2 (de) | 1996-05-02 |
| CS249191A3 (en) | 1992-03-18 |
| HU912674D0 (en) | 1992-01-28 |
| NZ260632A (en) | 1997-06-24 |
| NZ239328A (en) | 1996-03-26 |
| IL99168A (en) | 1995-07-31 |
| NO913140L (no) | 1992-02-14 |
| IE70596B1 (en) | 1996-12-11 |
| ES2079530T3 (es) | 1996-01-16 |
| JP3057828B2 (ja) | 2000-07-04 |
| GR3018187T3 (en) | 1996-02-29 |
| MX9100638A (es) | 1992-04-01 |
| EP0471296B1 (en) | 1995-11-08 |
| DE69114404D1 (de) | 1995-12-14 |
| NO179583B (no) | 1996-07-29 |
| AU637249B2 (en) | 1993-05-20 |
| KR100223133B1 (ko) | 1999-10-15 |
| IL99168A0 (en) | 1992-07-15 |
| IE912850A1 (en) | 1992-02-26 |
| NO913140D0 (no) | 1991-08-12 |
| CA2048980C (en) | 2003-05-13 |
| FI913799A0 (fi) | 1991-08-09 |
| CA2048980A1 (en) | 1992-02-14 |
| HUT58722A (en) | 1992-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO175980C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive 4- og 6-karbamater av physostigmin og mellomprodukter | |
| FI102067B1 (fi) | Menetelmä terapeuttisesti käyttökelpoisten 1-(substituoitu pyridinyyliamino)-1H-indol-5-yyli-substituoitujen karbamaattien valmistamiseksi | |
| PT92234A (pt) | Processo para a preparacao de 1,2,3,4-tetraidro-1,9-acridinodiaminas | |
| NO179583C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indoler | |
| FI96308C (fi) | Menetelmä terapeuttisesti käyttökelpoisten 9-aminotetrahydroakridiinien ja niiden johdannaisten valmistamiseksi | |
| NO177053C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive (1,2,3,4-tetrahydro-9-akridinimino)cykloheksankarboksylsyrer | |
| NO173783C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive, kondenserte heterodykliske derivater av 1,2,3,4-tetrahydroakridiner | |
| NO178372C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive karbamoyl-1-(pyrindinylalkyl)-1H-indoler |