NO179550C - Tachykinin reseptorantagonister - Google Patents

Tachykinin reseptorantagonister

Info

Publication number
NO179550C
NO179550C NO931364A NO931364A NO179550C NO 179550 C NO179550 C NO 179550C NO 931364 A NO931364 A NO 931364A NO 931364 A NO931364 A NO 931364A NO 179550 C NO179550 C NO 179550C
Authority
NO
Norway
Prior art keywords
receptor antagonists
tachykinin receptor
tachykinin
antagonists
receptor
Prior art date
Application number
NO931364A
Other languages
English (en)
Norwegian (no)
Other versions
NO179550B (no
NO931364L (no
NO931364D0 (no
Inventor
Hideaki Natsugari
Hideo Shirafuji
Takayuki Doi
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO931364D0 publication Critical patent/NO931364D0/no
Publication of NO931364L publication Critical patent/NO931364L/no
Publication of NO179550B publication Critical patent/NO179550B/no
Publication of NO179550C publication Critical patent/NO179550C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO931364A 1992-04-15 1993-04-14 Tachykinin reseptorantagonister NO179550C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9529192 1992-04-15

Publications (4)

Publication Number Publication Date
NO931364D0 NO931364D0 (no) 1993-04-14
NO931364L NO931364L (no) 1993-10-18
NO179550B NO179550B (no) 1996-07-22
NO179550C true NO179550C (no) 1996-10-30

Family

ID=14133676

Family Applications (1)

Application Number Title Priority Date Filing Date
NO931364A NO179550C (no) 1992-04-15 1993-04-14 Tachykinin reseptorantagonister

Country Status (11)

Country Link
US (1) US5523305A (fr)
EP (1) EP0566069A1 (fr)
KR (1) KR930021202A (fr)
CN (1) CN1083054A (fr)
AU (1) AU657045B2 (fr)
CA (1) CA2094117A1 (fr)
FI (1) FI931682A (fr)
HU (1) HUT70148A (fr)
NO (1) NO179550C (fr)
NZ (1) NZ247302A (fr)
TW (1) TW241258B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0634402A1 (fr) * 1993-07-14 1995-01-18 Takeda Chemical Industries, Ltd. Dérivés d'isoquinolinone, leur production et utilisation
TW263498B (fr) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd
US5770590A (en) * 1995-03-24 1998-06-23 Takeda Chemical Industries, Ltd. Cyclic compounds, their prudiction and use
ES2194937T3 (es) * 1995-03-24 2003-12-01 Takeda Chemical Industries Ltd Compuestos ciclicos, su produccion y uso como antagonistas de los receptores de taquiquinina.
AU2003211931A1 (en) * 2002-02-13 2003-09-04 Takeda Chemical Industries, Ltd. Jnk inhibitor
US7781457B2 (en) 2003-09-23 2010-08-24 Merck Sharp & Dohme Corp. Isoquinolinone potassium channel inhibitors
AU2004276268B2 (en) * 2003-09-23 2009-01-29 Merck Sharp & Dohme Corp. Isoquinoline potassium channel inhibitors
DK2729147T3 (en) 2011-07-04 2017-12-18 Irbm - Science Park S P A NK-1 RECEPTOR ANTAGONISTS FOR TREATMENT OF CORNOVA
RU2020131446A (ru) 2018-02-26 2022-03-28 Оспедале Сан Раффаэле С.Р.Л. Антагонисты nk-1 для применения в лечении глазной боли
EP4117673A1 (fr) 2020-03-11 2023-01-18 Ospedale San Raffaele S.r.l. Traitement d'une déficience en cellules souches

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2647902A (en) * 1951-02-16 1953-08-04 Smith Kline French Lab Method for the preparation of tetrahydroisoquinolone derivatives
US2809969A (en) * 1955-11-07 1957-10-15 Bristol Lab Inc Isoquinolone derivatives
US3247212A (en) * 1963-03-19 1966-04-19 Dow Chemical Co Thio substituted 3 amino isoquinolines
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils
DE2030675A1 (en) * 1969-06-23 1971-02-11 Arthur D Little, Inc , Cambridge, Mass (V St A) 3-amino-4-phenyl-isoquinoline derivs
IL45823A (en) * 1973-10-20 1977-10-31 Hoechst Ag Substituted 1-phenyl-4-alkyl(dialkyl or cyclic) aminoalkyl-1,4-dihydro-2h-isoquinoline-3-one derivatives
TW205037B (fr) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd
JPH03181465A (ja) * 1989-12-11 1991-08-07 Takeda Chem Ind Ltd キノリン誘導体
US5143919A (en) * 1990-08-17 1992-09-01 Takeda Chemical Industries, Ltd. Thienopyridine derivatives and their pharmaceutical use
JPH059179A (ja) * 1990-09-27 1993-01-19 Takeda Chem Ind Ltd 複素環化合物、その製造法及びacat阻害剤
DE69110828T2 (de) * 1990-10-16 1995-11-30 Takeda Chemical Industries Ltd Heterozyklische Aminderivate, deren Herstellung und deren Verwendung.

Also Published As

Publication number Publication date
US5523305A (en) 1996-06-04
CN1083054A (zh) 1994-03-02
TW241258B (fr) 1995-02-21
AU3566393A (en) 1993-10-21
CA2094117A1 (fr) 1993-10-16
FI931682A0 (fi) 1993-04-14
KR930021202A (ko) 1993-11-22
EP0566069A1 (fr) 1993-10-20
HUT70148A (en) 1995-09-28
AU657045B2 (en) 1995-02-23
FI931682A (fi) 1993-10-16
HU9301080D0 (en) 1993-06-28
NO179550B (no) 1996-07-22
NO931364L (no) 1993-10-18
NO931364D0 (no) 1993-04-14
NZ247302A (en) 1994-12-22

Similar Documents

Publication Publication Date Title
DE69207351D1 (de) Fibrinogen-Rezeptor-Antagoniste
NO972016D0 (no) Indolyl-Y-reseptorantagonister
NO951613D0 (no) Ikke-peptidyl tachykinin reseptorantagonister
FI971685A (fi) Takykiniini-antagonisteja
DE69327720D1 (de) Endothelin rezeptor antagonisten
FI961804A (fi) Endoteliinireseptoriantagonistit
DE69232072D1 (de) Endothelin-rezeptor-antagonisten
NO965608D0 (no) Vitronectin-reseptor-antagonister
NO983001D0 (no) Vitronectin-reseptor-antagonister
NO983003D0 (no) Vitronectin-reseptor-antagonister
DK0804419T3 (da) Quinolinderivater som tachykinin NK 3-receptor-antagonister
NO983002D0 (no) Vitronectin-reseptor-antagonister
DE69734833D1 (de) Vitronektin rezeptor antagonisten
EP0819005A4 (fr) 2-acylaminopropanamides en tant qu'antagonistes de recepteurs de tachykinine
EP0736007A4 (fr) Antagonistes non peptidiques des recepteurs des tachykinines
AU4718093A (en) Substituted amines as tachykinin receptor antagonists
FI924405A (fi) Lhrh-antagonister
HU9403676D0 (en) Non-peptide tachykinin receptor antagonists
MX9101311A (es) Antagonistas receptores de fibrinogeno
ID16742A (id) Antagonis reseptor endotelin
DK0699069T3 (da) Endothelinreceptorantagonister
KR960700722A (ko) 피브리노겐 수용체 길항제(Fibrinogen receptor antagonists)
NO179550C (no) Tachykinin reseptorantagonister
FI951798A0 (fi) Bentsofuraanijohdannaiset 5-HT1-kaltaisina reseptoriantagonisteina
GB9320799D0 (en) Fibrinogen receptor antagonists