NO179281C - Process for the preparation of enantioselective derivatives of phenyl isoserine and a process for the preparation of a derivative of baccatin-III or 10-desacetylbaccatin-III - Google Patents

Process for the preparation of enantioselective derivatives of phenyl isoserine and a process for the preparation of a derivative of baccatin-III or 10-desacetylbaccatin-III

Info

Publication number
NO179281C
NO179281C NO903688A NO903688A NO179281C NO 179281 C NO179281 C NO 179281C NO 903688 A NO903688 A NO 903688A NO 903688 A NO903688 A NO 903688A NO 179281 C NO179281 C NO 179281C
Authority
NO
Norway
Prior art keywords
preparation
iii
enantioselective
derivatives
desacetylbaccatin
Prior art date
Application number
NO903688A
Other languages
Norwegian (no)
Other versions
NO903688D0 (en
NO903688L (en
NO179281B (en
Inventor
Arlene Goncalves Correa
Jean-Noel Denis
Andrew-Elliot Greene
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8911162A external-priority patent/FR2651226B1/en
Priority claimed from FR8912825A external-priority patent/FR2652577B1/en
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of NO903688D0 publication Critical patent/NO903688D0/en
Publication of NO903688L publication Critical patent/NO903688L/en
Publication of NO179281B publication Critical patent/NO179281B/en
Publication of NO179281C publication Critical patent/NO179281C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Control Of Transmission Device (AREA)
  • Measuring Fluid Pressure (AREA)

Abstract

Process for the preparation of enantioselective preparation of phenylisoserine derivatives of general formula (I) in which R denotes a phenyl or tert-butoxy radical and R1 denotes a hydrogen atom or an alkyl radical containing 1 to 4 carbon atoms and R2 denotes a hydrogen atom or a group for protecting the alcohol functional group. <IMAGE>
NO903688A 1989-08-23 1990-08-22 Process for the preparation of enantioselective derivatives of phenyl isoserine and a process for the preparation of a derivative of baccatin-III or 10-desacetylbaccatin-III NO179281C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8911162A FR2651226B1 (en) 1989-08-23 1989-08-23 PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.
FR8912825A FR2652577B1 (en) 1989-10-02 1989-10-02 PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.

Publications (4)

Publication Number Publication Date
NO903688D0 NO903688D0 (en) 1990-08-22
NO903688L NO903688L (en) 1991-02-25
NO179281B NO179281B (en) 1996-06-03
NO179281C true NO179281C (en) 1996-09-11

Family

ID=26227528

Family Applications (1)

Application Number Title Priority Date Filing Date
NO903688A NO179281C (en) 1989-08-23 1990-08-22 Process for the preparation of enantioselective derivatives of phenyl isoserine and a process for the preparation of a derivative of baccatin-III or 10-desacetylbaccatin-III

Country Status (13)

Country Link
EP (1) EP0414610B1 (en)
JP (1) JP2740345B2 (en)
AT (1) ATE89815T1 (en)
CA (1) CA2023645C (en)
DE (1) DE69001732T2 (en)
DK (1) DK0414610T3 (en)
ES (1) ES2055368T3 (en)
FI (1) FI107333B (en)
GR (1) GR3007983T3 (en)
HU (1) HU207288B (en)
IL (1) IL95436A (en)
NO (1) NO179281C (en)
PT (1) PT95092B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658513B1 (en) * 1990-02-21 1994-02-04 Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF CIS-BETA-PHENYLGLYCIDIC- (2R, 3R) ACID.
FR2662440B1 (en) * 1990-05-22 1992-07-31 Rhone Poulenc Sante PROCESS FOR THE STEREOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.
FR2671799B1 (en) † 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa B-PHENYLISOSERINE- (2R, 3S), ITS SALTS, ITS PREPARATION AND ITS USE.
ES2230790T3 (en) * 1992-01-15 2005-05-01 E.R. SQUIBB &amp; SONS, INC. ENZYMATIC PROCEDURES FOR THE RESOLUTION OF ENANTIOMERIC BLENDS OF USEFUL COMPOUNDS AS INTERMEDIATES IN THE PREPARATION OF TAXANES.
DE69325454T2 (en) * 1992-04-17 2000-01-20 Abbott Lab TAXOL DERIVATIVES
FR2696454B1 (en) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Process for the stereoselective preparation of a beta-phenylisoserine derivative and its use for the preparation of Taxane derivatives.
US5420337A (en) * 1992-11-12 1995-05-30 E. R. Squibb & Sons, Inc. Enzymatic reduction method for the preparation of compounds useful for preparing taxanes
IL107950A (en) 1992-12-15 2001-04-30 Upjohn Co 7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
TW467896B (en) 1993-03-19 2001-12-11 Bristol Myers Squibb Co Novel β-lactams, methods for the preparation of taxanes and sidechain-bearing taxanes
FR2703353B1 (en) 1993-03-29 1995-05-05 Rhone Poulenc Rorer Sa Process for the preparation of beta-phenylisoserine derivatives.
EP0703909B1 (en) * 1993-06-11 2000-04-26 PHARMACIA &amp; UPJOHN COMPANY Delta 6,7 -taxols antineoplastic use and pharmaceutical compositions containing them
TW397866B (en) * 1993-07-14 2000-07-11 Bristol Myers Squibb Co Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
IL127598A (en) * 1994-01-28 2003-04-10 Upjohn Co Process for preparing isotaxol analogs
US5602272A (en) * 1994-06-21 1997-02-11 Bristol-Myers Squibb Company Reduction and resolution methods for the preparation of compounds useful as intemediates for preparing taxanes
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
JP3660385B2 (en) * 1995-03-01 2005-06-15 高砂香料工業株式会社 Process for producing optically active allophenylnorstatin derivative
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
FR2740451B1 (en) * 1995-10-27 1998-01-16 Seripharm NOVEL INTERMEDIATES FOR THE HEMISYNTHESIS OF TAXANES, THEIR PREPARATION METHODS AND THEIR USE IN THE GENERAL SYNTHESIS OF TAXANES
KR100225534B1 (en) * 1996-03-19 1999-10-15 정지석 Stereospecific process for preparing (2r,3s)-beta--phenylisoserine
KR20050044621A (en) 2001-11-30 2005-05-12 브리스톨-마이어스 스큅 컴퍼니 Paclitaxel solvates
EP2861256B1 (en) 2012-06-15 2019-10-23 The Brigham and Women's Hospital, Inc. Compositions for treating cancer and methods for making the same
WO2015153345A1 (en) 2014-04-03 2015-10-08 Invictus Oncology Pvt. Ltd. Supramolecular combinatorial therapeutics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520663A (en) * 1974-10-21 1978-08-09 Squibb & Sons Inc 7 - ( - hydroxy - - amino - propionamido) - cephalosporin derivatives
FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
JPH0383956A (en) 1991-04-09
EP0414610B1 (en) 1993-05-26
JP2740345B2 (en) 1998-04-15
CA2023645A1 (en) 1991-02-24
GR3007983T3 (en) 1993-08-31
NO903688D0 (en) 1990-08-22
FI904162A0 (en) 1990-08-22
PT95092B (en) 1997-04-30
ATE89815T1 (en) 1993-06-15
DK0414610T3 (en) 1993-06-14
HU207288B (en) 1993-03-29
ES2055368T3 (en) 1994-08-16
CA2023645C (en) 2002-03-26
HU905279D0 (en) 1991-02-28
NO903688L (en) 1991-02-25
HUT54626A (en) 1991-03-28
IL95436A0 (en) 1991-06-30
PT95092A (en) 1991-04-18
EP0414610A1 (en) 1991-02-27
FI107333B (en) 2001-07-13
DE69001732T2 (en) 1993-10-07
NO179281B (en) 1996-06-03
DE69001732D1 (en) 1993-07-01
IL95436A (en) 1996-07-23

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Legal Events

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