IL95436A0 - Method for the preparation of phenylisoserine derivatives - Google Patents

Method for the preparation of phenylisoserine derivatives

Info

Publication number
IL95436A0
IL95436A0 IL95436A IL9543690A IL95436A0 IL 95436 A0 IL95436 A0 IL 95436A0 IL 95436 A IL95436 A IL 95436A IL 9543690 A IL9543690 A IL 9543690A IL 95436 A0 IL95436 A0 IL 95436A0
Authority
IL
Israel
Prior art keywords
preparation
denotes
phenylisoserine derivatives
hydrogen atom
phenylisoserine
Prior art date
Application number
IL95436A
Other versions
IL95436A (en
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8911162A external-priority patent/FR2651226B1/en
Priority claimed from FR8912825A external-priority patent/FR2652577B1/en
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of IL95436A0 publication Critical patent/IL95436A0/en
Publication of IL95436A publication Critical patent/IL95436A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Control Of Transmission Device (AREA)
  • Measuring Fluid Pressure (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Process for the preparation of enantioselective preparation of phenylisoserine derivatives of general formula (I) in which R denotes a phenyl or tert-butoxy radical and R1 denotes a hydrogen atom or an alkyl radical containing 1 to 4 carbon atoms and R2 denotes a hydrogen atom or a group for protecting the alcohol functional group. <IMAGE>
IL9543690A 1989-08-23 1990-08-20 Method for the preparation of phenzlisoserine derivatives IL95436A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8911162A FR2651226B1 (en) 1989-08-23 1989-08-23 PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.
FR8912825A FR2652577B1 (en) 1989-10-02 1989-10-02 PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.

Publications (2)

Publication Number Publication Date
IL95436A0 true IL95436A0 (en) 1991-06-30
IL95436A IL95436A (en) 1996-07-23

Family

ID=26227528

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9543690A IL95436A (en) 1989-08-23 1990-08-20 Method for the preparation of phenzlisoserine derivatives

Country Status (13)

Country Link
EP (1) EP0414610B1 (en)
JP (1) JP2740345B2 (en)
AT (1) ATE89815T1 (en)
CA (1) CA2023645C (en)
DE (1) DE69001732T2 (en)
DK (1) DK0414610T3 (en)
ES (1) ES2055368T3 (en)
FI (1) FI107333B (en)
GR (1) GR3007983T3 (en)
HU (1) HU207288B (en)
IL (1) IL95436A (en)
NO (1) NO179281C (en)
PT (1) PT95092B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658513B1 (en) * 1990-02-21 1994-02-04 Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF CIS-BETA-PHENYLGLYCIDIC- (2R, 3R) ACID.
FR2662440B1 (en) * 1990-05-22 1992-07-31 Rhone Poulenc Sante PROCESS FOR THE STEREOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.
FR2671799B1 (en) † 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa B-PHENYLISOSERINE- (2R, 3S), ITS SALTS, ITS PREPARATION AND ITS USE.
CA2434312A1 (en) * 1992-01-15 1993-07-16 Ramesh N. Patel Enzymatic processes for resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
WO1993021173A1 (en) * 1992-04-17 1993-10-28 Abbott Laboratories Taxol derivatives
FR2696454B1 (en) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Process for the stereoselective preparation of a beta-phenylisoserine derivative and its use for the preparation of Taxane derivatives.
US5420337A (en) * 1992-11-12 1995-05-30 E. R. Squibb & Sons, Inc. Enzymatic reduction method for the preparation of compounds useful for preparing taxanes
IL107950A (en) 1992-12-15 2001-04-30 Upjohn Co 7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
TW467896B (en) 1993-03-19 2001-12-11 Bristol Myers Squibb Co Novel β-lactams, methods for the preparation of taxanes and sidechain-bearing taxanes
FR2703353B1 (en) * 1993-03-29 1995-05-05 Rhone Poulenc Rorer Sa Process for the preparation of beta-phenylisoserine derivatives.
ES2145829T3 (en) * 1993-06-11 2000-07-16 Upjohn Co ANTINEOPLASIC USE OF DELTA 6,7-TAXOLS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
TW397866B (en) 1993-07-14 2000-07-11 Bristol Myers Squibb Co Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs
US5602272A (en) * 1994-06-21 1997-02-11 Bristol-Myers Squibb Company Reduction and resolution methods for the preparation of compounds useful as intemediates for preparing taxanes
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
JP3660385B2 (en) * 1995-03-01 2005-06-15 高砂香料工業株式会社 Process for producing optically active allophenylnorstatin derivative
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
FR2740451B1 (en) * 1995-10-27 1998-01-16 Seripharm NOVEL INTERMEDIATES FOR THE HEMISYNTHESIS OF TAXANES, THEIR PREPARATION METHODS AND THEIR USE IN THE GENERAL SYNTHESIS OF TAXANES
KR100225534B1 (en) * 1996-03-19 1999-10-15 정지석 Stereospecific process for preparing (2r,3s)-beta--phenylisoserine
PL368945A1 (en) 2001-11-30 2005-04-04 Bristol-Myers Squibb Company Paclitaxel solvates
CN104582732A (en) 2012-06-15 2015-04-29 布里格姆及妇女医院股份有限公司 Compositions for treating cancer and methods for making the same
CA2944401A1 (en) 2014-04-03 2015-10-08 Invictus Oncology Pvt. Ltd. Supramolecular combinatorial therapeutics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520663A (en) * 1974-10-21 1978-08-09 Squibb & Sons Inc 7 - ( - hydroxy - - amino - propionamido) - cephalosporin derivatives
FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
FI904162A0 (en) 1990-08-22
GR3007983T3 (en) 1993-08-31
CA2023645C (en) 2002-03-26
HUT54626A (en) 1991-03-28
FI107333B (en) 2001-07-13
EP0414610A1 (en) 1991-02-27
ES2055368T3 (en) 1994-08-16
PT95092B (en) 1997-04-30
ATE89815T1 (en) 1993-06-15
JP2740345B2 (en) 1998-04-15
JPH0383956A (en) 1991-04-09
NO179281C (en) 1996-09-11
NO179281B (en) 1996-06-03
NO903688D0 (en) 1990-08-22
IL95436A (en) 1996-07-23
DE69001732D1 (en) 1993-07-01
DE69001732T2 (en) 1993-10-07
CA2023645A1 (en) 1991-02-24
EP0414610B1 (en) 1993-05-26
HU905279D0 (en) 1991-02-28
PT95092A (en) 1991-04-18
NO903688L (en) 1991-02-25
DK0414610T3 (en) 1993-06-14
HU207288B (en) 1993-03-29

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