GB1520663A - 7 - ( - hydroxy - - amino - propionamido) - cephalosporin derivatives - Google Patents

7 - ( - hydroxy - - amino - propionamido) - cephalosporin derivatives

Info

Publication number
GB1520663A
GB1520663A GB4079475A GB4079475A GB1520663A GB 1520663 A GB1520663 A GB 1520663A GB 4079475 A GB4079475 A GB 4079475A GB 4079475 A GB4079475 A GB 4079475A GB 1520663 A GB1520663 A GB 1520663A
Authority
GB
United Kingdom
Prior art keywords
amino
propionamido
hydroxy
cephalosporin
hcl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4079475A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB1520663A publication Critical patent/GB1520663A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1520663 7 - (alpha - Hydroxy - # - amino - propionamido) - cephalosporin silyl esters E R SQUIBB & SONS Inc 6 Oct 1975 [21 Oct 1974] 40794/75 Heading C3S [Also in Division C2] Novel compounds I in which R is tri(C1-7 alkyl)silyl, R1 is C1-7 alkyl, a C4-6 alicyclic group, phenyl or thienyl; and R2 is H, OH, C1-7 alkanoyloxy or HCl-S- (where HCl is thiadiazolyl, oxadiazolyl thiatriazolyl, tetrazolyl or N-oxido-pyridyl (each optionally C1-7 alkylated‹ are prepared by acylation of the corresponding 7-amino cephalosporin followed if desired by esterification or salification of the free acid. Compounds I have anti-microbial activity and form pharmaceutical compositions for administration orally or parenterally.
GB4079475A 1974-10-21 1975-10-06 7 - ( - hydroxy - - amino - propionamido) - cephalosporin derivatives Expired GB1520663A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51629874A 1974-10-21 1974-10-21
US51629774A 1974-10-21 1974-10-21

Publications (1)

Publication Number Publication Date
GB1520663A true GB1520663A (en) 1978-08-09

Family

ID=27058787

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4079475A Expired GB1520663A (en) 1974-10-21 1975-10-06 7 - ( - hydroxy - - amino - propionamido) - cephalosporin derivatives

Country Status (4)

Country Link
JP (1) JPS5165795A (en)
DE (1) DE2545818A1 (en)
FR (1) FR2288522A1 (en)
GB (1) GB1520663A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304670A (en) * 1989-08-23 1994-04-19 Centre National De La Recherche Scientifique Process for the enantioselective preparation of phenylisoserine derivatives

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL95436A (en) * 1989-08-23 1996-07-23 Centre Nat Rech Scient Method for the preparation of phenzlisoserine derivatives
FR2651226B1 (en) * 1989-08-23 1993-01-08 Centre Nat Rech Scient PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304670A (en) * 1989-08-23 1994-04-19 Centre National De La Recherche Scientifique Process for the enantioselective preparation of phenylisoserine derivatives

Also Published As

Publication number Publication date
JPS5165795A (en) 1976-06-07
DE2545818A1 (en) 1976-04-29
FR2288522A1 (en) 1976-05-21
FR2288522B1 (en) 1980-05-09

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee