NO170516C - Fremgangsmaate for fremstilling av en formulering av beclomethasondipropionat - Google Patents

Fremgangsmaate for fremstilling av en formulering av beclomethasondipropionat

Info

Publication number
NO170516C
NO170516C NO863321A NO863321A NO170516C NO 170516 C NO170516 C NO 170516C NO 863321 A NO863321 A NO 863321A NO 863321 A NO863321 A NO 863321A NO 170516 C NO170516 C NO 170516C
Authority
NO
Norway
Prior art keywords
beclomethasondipropionate
formulation
preparing
procedure
beclomethasondipropionate formulation
Prior art date
Application number
NO863321A
Other languages
English (en)
Other versions
NO863321L (no
NO863321D0 (no
NO170516B (no
Inventor
Philip Anthony Jinks
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of NO863321L publication Critical patent/NO863321L/no
Publication of NO863321D0 publication Critical patent/NO863321D0/no
Publication of NO170516B publication Critical patent/NO170516B/no
Publication of NO170516C publication Critical patent/NO170516C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
NO863321A 1984-12-19 1986-08-18 Fremgangsmaate for fremstilling av en formulering av beclomethasondipropionat NO170516C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848432063A GB8432063D0 (en) 1984-12-19 1984-12-19 Physically modified steroids
PCT/GB1985/000588 WO1986003750A1 (en) 1984-12-19 1985-12-16 Physically modified beclomethasone dipropionate suitable for use in aerosols

Publications (4)

Publication Number Publication Date
NO863321L NO863321L (no) 1986-08-18
NO863321D0 NO863321D0 (no) 1986-08-18
NO170516B NO170516B (no) 1992-07-20
NO170516C true NO170516C (no) 1992-10-28

Family

ID=10571434

Family Applications (1)

Application Number Title Priority Date Filing Date
NO863321A NO170516C (no) 1984-12-19 1986-08-18 Fremgangsmaate for fremstilling av en formulering av beclomethasondipropionat

Country Status (14)

Country Link
US (1) US4810488A (no)
EP (1) EP0205530B1 (no)
JP (1) JPH0714880B2 (no)
KR (1) KR910004338B1 (no)
AU (1) AU587010B2 (no)
CA (1) CA1253806A (no)
DE (1) DE3568334D1 (no)
ES (1) ES8702136A1 (no)
GB (1) GB8432063D0 (no)
IE (1) IE58686B1 (no)
NO (1) NO170516C (no)
NZ (1) NZ214544A (no)
WO (1) WO1986003750A1 (no)
ZA (1) ZA859631B (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
DE4003270A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
US5118494A (en) * 1990-03-23 1992-06-02 Minnesota Mining And Manufacturing Company Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
EP0536235B1 (en) * 1990-06-29 1997-01-22 FISONS plc Pressurised aerosol compositions
DK0553298T3 (da) * 1990-10-18 1995-04-18 Minnesota Mining & Mfg Aerosolformulering omfattende beclomethason-17,21-dipropionat
MX9203481A (es) * 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
US5916540A (en) 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
JP3026841B2 (ja) * 1991-12-12 2000-03-27 グラクソ、グループ、リミテッド 医 薬
TW244350B (no) * 1991-12-14 1995-04-01 Hoechst Ag
DK0617610T3 (da) * 1991-12-18 1997-10-06 Minnesota Mining & Mfg Suspensionsaerosolformuleringer.
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
US5202110A (en) * 1992-01-22 1993-04-13 Virginia Commonwealth University Formulations for delivery of beclomethasone diproprionate by metered dose inhalers containing no chlorofluorocarbon propellants
GB9202519D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
US5833950A (en) * 1992-07-31 1998-11-10 Glaxo Group Limited Aerosol formulations containing beclomethasone dipropionate-1, 1, 1, 2-tetrafluoroethane solvate
MX9304585A (es) 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
US6013245A (en) * 1995-01-26 2000-01-11 Glaxo Group Limited Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant
US5747001A (en) * 1995-02-24 1998-05-05 Nanosystems, L.L.C. Aerosols containing beclomethazone nanoparticle dispersions
ATE274341T1 (de) 1995-02-24 2004-09-15 Elan Pharma Int Ltd Nanopartikel-dispersionen enthaltende aerosole
IL126701A (en) * 1996-04-29 2001-08-08 Dura Pharma Inc Inhaler system for inhalation of a dry powder drug
GB9826286D0 (en) * 1998-12-01 1999-01-20 Rhone Poulence Rorer Limited Process
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US7582284B2 (en) * 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
US8912174B2 (en) 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
US7811606B2 (en) 2003-04-16 2010-10-12 Dey, L.P. Nasal pharmaceutical formulations and methods of using the same
US9808471B2 (en) 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
AU2004272077A1 (en) * 2003-09-10 2005-03-24 Map Pharmaceuticals, Inc. Aerosol formulations for delivery of dihydroergotamine to the systemic circulation via pulmonary inhalation
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
CA2677838C (en) * 2007-02-11 2017-08-01 Map Pharmaceuticals, Inc. Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
TWI695723B (zh) 2009-05-29 2020-06-11 美商沛爾醫療股份有限公司 用於經由呼吸道輸送活性劑的組成物以及相關方法與系統
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
US20110171141A1 (en) * 2009-06-26 2011-07-14 Kellerman Donald J Administration of dihydroergotamine mesylate particles using a metered dose inhaler
US20140275517A1 (en) 2013-03-15 2014-09-18 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
IT1121513B (it) * 1979-05-28 1986-04-02 Chiesi Farma Spa Processo per la conversione di umo steroide antiinfiammatorio in una forma suscettibile di essere somministarta come aerosol
EP0039369B1 (en) * 1980-05-02 1983-06-15 Schering Corporation Beclomethasone ester solvates, process for their preparation, and preparation of a formulation
GB2107715B (en) * 1981-10-19 1985-11-13 Glaxo Group Ltd Micronised beclomethasone dipropionate monohydrate and powder inhalation compositions containing it
KR880001237B1 (ko) * 1984-07-25 1988-07-12 호비온 인터 리미티드 베클로메타손 17,21-디프로피오네이트의 용매화합물의 제조방법

Also Published As

Publication number Publication date
WO1986003750A1 (en) 1986-07-03
IE853231L (en) 1986-06-19
GB8432063D0 (en) 1985-01-30
NZ214544A (en) 1989-04-26
NO863321L (no) 1986-08-18
ZA859631B (en) 1987-05-27
AU5308786A (en) 1986-07-22
KR870700070A (ko) 1987-02-28
CA1253806A (en) 1989-05-09
DE3568334D1 (en) 1989-03-30
KR910004338B1 (ko) 1991-06-26
AU587010B2 (en) 1989-08-03
JPH0714880B2 (ja) 1995-02-22
IE58686B1 (en) 1993-11-03
EP0205530B1 (en) 1989-02-22
NO863321D0 (no) 1986-08-18
EP0205530A1 (en) 1986-12-30
ES550076A0 (es) 1986-12-16
JPS62501706A (ja) 1987-07-09
US4810488A (en) 1989-03-07
NO170516B (no) 1992-07-20
ES8702136A1 (es) 1986-12-16

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JUNE 2003