NO169069C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-alkoksy-2-aminopropylaminderivater - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-alkoksy-2-aminopropylaminderivaterInfo
- Publication number
- NO169069C NO169069C NO870533A NO870533A NO169069C NO 169069 C NO169069 C NO 169069C NO 870533 A NO870533 A NO 870533A NO 870533 A NO870533 A NO 870533A NO 169069 C NO169069 C NO 169069C
- Authority
- NO
- Norway
- Prior art keywords
- aminopropylamine
- alcoxy
- derivatives
- preparation
- therapeutic active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/828,923 US4727072A (en) | 1986-02-12 | 1986-02-12 | 3-alkoxy-2-aminopropylamines compositions and use as cardiovascular agents |
Publications (4)
Publication Number | Publication Date |
---|---|
NO870533D0 NO870533D0 (no) | 1987-02-11 |
NO870533L NO870533L (no) | 1987-08-13 |
NO169069B NO169069B (no) | 1992-01-27 |
NO169069C true NO169069C (no) | 1992-05-06 |
Family
ID=25253093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO870533A NO169069C (no) | 1986-02-12 | 1987-02-11 | Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-alkoksy-2-aminopropylaminderivater |
Country Status (12)
Country | Link |
---|---|
US (1) | US4727072A (zh) |
EP (1) | EP0237191A1 (zh) |
JP (1) | JPS62215577A (zh) |
KR (1) | KR870007882A (zh) |
CN (1) | CN87100686A (zh) |
AU (2) | AU599954B2 (zh) |
DK (1) | DK69987A (zh) |
FI (1) | FI870580A (zh) |
HU (1) | HU198032B (zh) |
NO (1) | NO169069C (zh) |
NZ (1) | NZ219161A (zh) |
ZA (1) | ZA87988B (zh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4727072A (en) * | 1986-02-12 | 1988-02-23 | Mcneilab, Inc. | 3-alkoxy-2-aminopropylamines compositions and use as cardiovascular agents |
DE3726633A1 (de) * | 1987-08-11 | 1989-02-23 | Boehringer Mannheim Gmbh | Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
DE3726632A1 (de) * | 1987-08-11 | 1989-05-18 | Boehringer Mannheim Gmbh | 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
US4888335A (en) * | 1988-07-25 | 1989-12-19 | Mcneilab, Inc. | 3-alkoxy-2-aminopropyl heterocyclic amines and their use as cardiovascular agents |
US5185362A (en) * | 1988-09-14 | 1993-02-09 | Mcneilab, Inc. | Diphenylamine cardiovascular agents, compositions and use |
EP0507488A1 (en) * | 1991-03-27 | 1992-10-07 | Merck & Co. Inc. | Inhibitors of HIV-1 reverse transcriptase |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
EP1889198B1 (en) | 2005-04-28 | 2014-11-26 | Proteus Digital Health, Inc. | Pharma-informatics system |
WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
DK3395372T3 (da) | 2009-02-20 | 2022-04-19 | Enhanx Biopharm Inc | System til afgivelse af glutathion-baseret medikament |
EP2427178B1 (en) | 2009-05-06 | 2023-01-04 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US30577A (en) * | 1860-11-06 | Truss-bridge | ||
BE795735A (fr) | 1972-03-06 | 1973-06-18 | Cerm Cent Europ Rech Mauvernay | Nouvelles ethylenediamines substituees a activite cardiovasculaire |
US4430338A (en) * | 1980-09-30 | 1984-02-07 | Akzo N.V. | Method of treatment patients at risk of sudden death |
NO149468C (no) * | 1981-07-17 | 1984-04-25 | Vefi As | Rykkegrep. |
DK156396C (da) * | 1983-09-27 | 1990-01-08 | Cerm Cent Europ Rech Mauvernay | 2-(n-pyrrolidino)-3-isobutoxy-n-substituerede phenyl-n-benzyl-propylamin-forbindelser og farmaceutiske midler indeholdende disse |
DE3468684D1 (de) * | 1983-11-11 | 1988-02-18 | Akzo Nv | Ether of n-propanolamine derivative |
GB8330197D0 (en) * | 1983-11-11 | 1983-12-21 | Akzo Nv | Ether of n-propanolamine derivative |
FR2558161B1 (fr) * | 1984-01-18 | 1987-01-23 | Cerm Cent Europ Rech Mauvernay | 3-alkoxy 2-(n-pyrrolidino) n-furylmethyl ou n-thienylmethyl n-pyridyl propylamines, leur preparation et leur application en therapeutique |
US4727072A (en) * | 1986-02-12 | 1988-02-23 | Mcneilab, Inc. | 3-alkoxy-2-aminopropylamines compositions and use as cardiovascular agents |
-
1986
- 1986-02-12 US US06/828,923 patent/US4727072A/en not_active Expired - Lifetime
-
1987
- 1987-02-03 NZ NZ219161A patent/NZ219161A/xx unknown
- 1987-02-11 KR KR870001106A patent/KR870007882A/ko not_active Application Discontinuation
- 1987-02-11 NO NO870533A patent/NO169069C/no unknown
- 1987-02-11 ZA ZA87988A patent/ZA87988B/xx unknown
- 1987-02-11 FI FI870580A patent/FI870580A/fi not_active Application Discontinuation
- 1987-02-11 EP EP87301162A patent/EP0237191A1/en not_active Ceased
- 1987-02-11 DK DK069987A patent/DK69987A/da not_active Application Discontinuation
- 1987-02-11 AU AU68680/87A patent/AU599954B2/en not_active Ceased
- 1987-02-12 HU HU87550A patent/HU198032B/hu not_active IP Right Cessation
- 1987-02-12 CN CN198787100686A patent/CN87100686A/zh active Pending
- 1987-02-12 JP JP62028371A patent/JPS62215577A/ja active Pending
-
1990
- 1990-07-26 AU AU59889/90A patent/AU621003B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU599954B2 (en) | 1990-08-02 |
NO169069B (no) | 1992-01-27 |
KR870007882A (ko) | 1987-09-22 |
AU6868087A (en) | 1987-08-13 |
AU5988990A (en) | 1990-11-15 |
CN87100686A (zh) | 1987-10-14 |
FI870580A0 (fi) | 1987-02-11 |
NZ219161A (en) | 1989-03-29 |
HU198032B (en) | 1989-07-28 |
NO870533D0 (no) | 1987-02-11 |
DK69987D0 (da) | 1987-02-11 |
NO870533L (no) | 1987-08-13 |
AU621003B2 (en) | 1992-02-27 |
US4727072A (en) | 1988-02-23 |
ZA87988B (en) | 1988-09-28 |
HUT46660A (en) | 1988-11-28 |
DK69987A (da) | 1987-08-13 |
FI870580A (fi) | 1987-08-13 |
EP0237191A1 (en) | 1987-09-16 |
JPS62215577A (ja) | 1987-09-22 |
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