NO150885C - Analogifremgangsmaate til fremstilling av farmakologisk virksomme muramylpeptider - Google Patents

Analogifremgangsmaate til fremstilling av farmakologisk virksomme muramylpeptider

Info

Publication number
NO150885C
NO150885C NO803030A NO803030A NO150885C NO 150885 C NO150885 C NO 150885C NO 803030 A NO803030 A NO 803030A NO 803030 A NO803030 A NO 803030A NO 150885 C NO150885 C NO 150885C
Authority
NO
Norway
Prior art keywords
lower alkyl
formula
cycloalkyl
preparation
hydrogen
Prior art date
Application number
NO803030A
Other languages
English (en)
Norwegian (no)
Other versions
NO150885B (no
NO803030L (no
Inventor
Gerhard Baschang
Jaroslav Stanek
Lajos Tarcsay
Albert Hartmann
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO803030L publication Critical patent/NO803030L/no
Publication of NO150885B publication Critical patent/NO150885B/no
Publication of NO150885C publication Critical patent/NO150885C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Arrangement Or Mounting Of Control Devices For Change-Speed Gearing (AREA)
  • Steroid Compounds (AREA)
NO803030A 1979-10-12 1980-10-10 Analogifremgangsmaate til fremstilling av farmakologisk virksomme muramylpeptider NO150885C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH921979 1979-10-12

Publications (3)

Publication Number Publication Date
NO803030L NO803030L (no) 1981-04-13
NO150885B NO150885B (no) 1984-09-24
NO150885C true NO150885C (no) 1985-01-09

Family

ID=4349637

Family Applications (1)

Application Number Title Priority Date Filing Date
NO803030A NO150885C (no) 1979-10-12 1980-10-10 Analogifremgangsmaate til fremstilling av farmakologisk virksomme muramylpeptider

Country Status (18)

Country Link
US (1) US4323560A (pt)
EP (1) EP0027258B1 (pt)
JP (1) JPS5681597A (pt)
AT (1) ATE13301T1 (pt)
AU (1) AU542377B2 (pt)
CA (1) CA1183525A (pt)
DD (1) DD155984A5 (pt)
DE (1) DE3070649D1 (pt)
DK (1) DK429080A (pt)
ES (1) ES495843A0 (pt)
FI (1) FI803077A (pt)
GR (1) GR70671B (pt)
HU (1) HU185283B (pt)
IL (1) IL61248A (pt)
NO (1) NO150885C (pt)
NZ (1) NZ195235A (pt)
PT (1) PT71906B (pt)
ZA (1) ZA806239B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI75578C (fi) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
EP0056560A1 (de) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Antibiotische Präparate mit gesteigerter Wirksamkeit, Verfahren zu deren Herstellung und Verfahren zur Steigerung der antibiotischen Wirkung von Antibiotika
GR78246B (pt) * 1981-01-23 1984-09-26 Ciba Geigy Ag
US5189017A (en) * 1982-07-23 1993-02-23 Ciba-Geigy Corporation Use of sugar derivatives for the prophylaxis and treatment of virus infections
EP0102319B1 (de) * 1982-07-23 1987-08-19 Ciba-Geigy Ag Verwendung von Muramylpeptiden oder deren Analogen zur Prophylaxe und Therapie von Virusinfektionen
ATE23536T1 (de) * 1982-07-23 1986-11-15 Ciba Geigy Ag Neue muramylpeptide und verfahren zu ihrer herstellung.
US5334583A (en) * 1982-07-23 1994-08-02 Ciba-Geigy Corp. Use of sugar derivatives for the prophylaxis and treatment of virus infections
US4933179A (en) * 1983-08-22 1990-06-12 Syntex (U.S.A.) Inc. Feline leukemia virus antigen vaccines
US4772466A (en) * 1983-08-22 1988-09-20 Syntex (U.S.A.) Inc. Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4606918A (en) * 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4770874A (en) * 1983-08-22 1988-09-13 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
DE3572491D1 (en) * 1984-07-25 1989-09-28 Ciba Geigy Ag Phosphatidyl compounds, process for their preparation and their use
US4885285A (en) * 1984-09-13 1989-12-05 Ciba-Geigy Corporation Phosphorus compounds, processes for their manufacture, and their use
US5106963A (en) * 1984-12-28 1992-04-21 Miles, Inc., Successor In Interest To Technicon Instruments Corp. Phospholipid conjugates and their preparation
US4873322A (en) * 1986-01-24 1989-10-10 Ciba-Geigy Corporation Saccharide derivatives and processes for their manufacture
US4916118A (en) * 1986-08-18 1990-04-10 Board Of Regents, The University Of Texas System Pharmaceutical administration systems containing chemotactic peptides
US5554372A (en) * 1986-09-22 1996-09-10 Emory University Methods and vaccines comprising surface-active copolymers
US5811088A (en) * 1987-02-20 1998-09-22 Emory University Antiinfective compounds and methods of use
US5674911A (en) * 1987-02-20 1997-10-07 Cytrx Corporation Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use
HU212924B (en) * 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
US20020123476A1 (en) * 1991-03-19 2002-09-05 Emanuele R. Martin Therapeutic delivery compositions and methods of use thereof
US7202225B1 (en) 1993-10-15 2007-04-10 Emanuele R Martin Therapeutic delivery compositions and methods of use thereof
HUT67762A (en) * 1991-03-19 1995-04-28 Cytrx Corp Polyoxypropylene/polyoxiethylene copolymers with improved biological activity and process for producing thereof
US6933286B2 (en) 1991-03-19 2005-08-23 R. Martin Emanuele Therapeutic delivery compositions and methods of use thereof
US5622649A (en) * 1991-06-27 1997-04-22 Emory University Multiple emulsions and methods of preparation
US6309642B1 (en) 1997-04-28 2001-10-30 The Research And Development Institute, Inc. Peptides which mimic candida carbohydrate epitopes and their use in a vaccine
US6488929B2 (en) 1994-05-23 2002-12-03 Montana State University Candida albicans phosphomannan complex as a vaccine
WO1995031998A1 (en) * 1994-05-23 1995-11-30 The Research & Development Institute, Inc. Candida albicans adhesin as a vaccine
US20030072775A1 (en) * 1997-04-28 2003-04-17 The Research And Development Institute Inc. Peptides which mimic candida carbohydrate epitopes and their use in a vaccine
CN103408635B (zh) * 2013-06-27 2015-06-17 深圳翰宇药业股份有限公司 一种合成米伐木肽的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
US4153684A (en) * 1976-03-10 1979-05-08 Agence Nationale De Valorisation De La Recherche (Anvar) Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives
US4082736A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
US4082735A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
FI75578C (fi) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.

Also Published As

Publication number Publication date
ATE13301T1 (de) 1985-06-15
PT71906A (en) 1980-11-01
CA1183525A (en) 1985-03-05
ES8106135A1 (es) 1981-07-16
ES495843A0 (es) 1981-07-16
HU185283B (en) 1984-12-28
IL61248A (en) 1984-10-31
IL61248A0 (en) 1980-12-31
PT71906B (en) 1981-08-31
DK429080A (da) 1981-04-13
NO150885B (no) 1984-09-24
NZ195235A (en) 1983-06-14
JPS5681597A (en) 1981-07-03
FI803077A (fi) 1981-04-13
EP0027258A1 (de) 1981-04-22
DD155984A5 (de) 1982-07-21
US4323560A (en) 1982-04-06
DE3070649D1 (en) 1985-06-20
ZA806239B (en) 1981-10-28
AU542377B2 (en) 1985-02-21
NO803030L (no) 1981-04-13
EP0027258B1 (de) 1985-05-15
GR70671B (pt) 1982-12-06
AU6315380A (en) 1981-04-16

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