NO144385C - INTERMEDIATE FOR THE PREPARATION OF NEW PENTANOR PROSTAGLANDINES OF THE E OR F SERIES - Google Patents

INTERMEDIATE FOR THE PREPARATION OF NEW PENTANOR PROSTAGLANDINES OF THE E OR F SERIES

Info

Publication number
NO144385C
NO144385C NO743616A NO743616A NO144385C NO 144385 C NO144385 C NO 144385C NO 743616 A NO743616 A NO 743616A NO 743616 A NO743616 A NO 743616A NO 144385 C NO144385 C NO 144385C
Authority
NO
Norway
Prior art keywords
prostaglandines
pentanor
series
preparation
new
Prior art date
Application number
NO743616A
Other languages
Norwegian (no)
Other versions
NO743616L (en
NO144385B (en
Inventor
Hans Jurgen Ernst Hess
Thomas Ken Schaaf
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO743616L publication Critical patent/NO743616L/en
Application filed by Pfizer filed Critical Pfizer
Publication of NO144385B publication Critical patent/NO144385B/en
Publication of NO144385C publication Critical patent/NO144385C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018—Esters of cycloaliphatic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
NO743616A 1972-11-08 1974-10-07 INTERMEDIATE FOR THE PREPARATION OF NEW PENTANOR PROSTAGLANDINES OF THE E OR F SERIES NO144385C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30475072A 1972-11-08 1972-11-08

Publications (3)

Publication Number Publication Date
NO743616L NO743616L (en) 1974-05-09
NO144385B NO144385B (en) 1981-05-11
NO144385C true NO144385C (en) 1981-08-19

Family

ID=23177829

Family Applications (2)

Application Number Title Priority Date Filing Date
NO4294/73A NO143663C (en) 1972-11-08 1973-11-08 ANALOGY PROCEDURE FOR PREPARING A PHYSIOLOGY ACTIVE PROSTAGLAND CONNECTION OF THE E OR F SERIES
NO743616A NO144385C (en) 1972-11-08 1974-10-07 INTERMEDIATE FOR THE PREPARATION OF NEW PENTANOR PROSTAGLANDINES OF THE E OR F SERIES

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO4294/73A NO143663C (en) 1972-11-08 1973-11-08 ANALOGY PROCEDURE FOR PREPARING A PHYSIOLOGY ACTIVE PROSTAGLAND CONNECTION OF THE E OR F SERIES

Country Status (20)

Country Link
JP (1) JPS5714347B2 (en)
AT (1) AT345999B (en)
BE (1) BE807046A (en)
CA (1) CA1033727A (en)
CH (1) CH593930A5 (en)
DE (1) DE2355731C3 (en)
DK (1) DK143499C (en)
ES (3) ES420386A1 (en)
FI (1) FI58912C (en)
FR (3) FR2205338B1 (en)
GB (1) GB1456838A (en)
IE (1) IE40043B1 (en)
IL (2) IL50310A (en)
IN (1) IN139265B (en)
NL (1) NL7315307A (en)
NO (2) NO143663C (en)
PH (2) PH13261A (en)
SE (4) SE412229B (en)
SU (2) SU667131A3 (en)
ZA (1) ZA738595B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431561A (en) * 1973-01-31 1976-04-07 Ici Ltd Cyclopentane derivatives
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
JPS5823393B2 (en) * 1974-03-14 1983-05-14 オノヤクヒンコウギヨウ カブシキガイシヤ prostaglandin
US4028396A (en) * 1975-07-02 1977-06-07 American Cyanamid Company 16,16-Spirocycloalkyl prostaglandin derivatives
NZ183136A (en) * 1976-02-11 1978-11-13 Miles Lab Monospiroalkyl derivatives of prostaclandis and pharmaceutical compositions
US4074063A (en) * 1976-02-11 1978-02-14 Miles Laboratories, Inc. Bicycloalkyl derivatives of prostaglandins
US4404372A (en) * 1977-06-13 1983-09-13 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandin derivatives
DE2753995A1 (en) * 1977-12-03 1979-06-07 Bayer Ag NEW BICYCLOALKENYL PROSTAGLANDINS AND THE METHOD OF MANUFACTURING THEM
WO1999012898A1 (en) * 1997-09-09 1999-03-18 The Procter & Gamble Company Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
US5977173A (en) * 1997-09-09 1999-11-02 Wos; John August Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists
ATE310721T1 (en) * 1997-09-09 2005-12-15 AROMATIC C16-C20-SUBSTITUTED TETRAHYDRO-PROSTAGLANDINS USABLE LIKE FP AGONISTS
EP1159266B1 (en) 1999-03-05 2004-11-03 Duke University C-16 unsaturated fp-selective prostaglandins analogs
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
DE502007000840D1 (en) * 2007-11-28 2009-07-16 Bauer Maschinen Gmbh winch
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20230097470A1 (en) * 2021-08-23 2023-03-30 Chirogate International Inc. Processes and intermediates for the preparations of carboprost and carboprost tromethamine, and carboprost tromethamine prepared therefrom

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4864073A (en) * 1971-04-30 1973-09-05

Also Published As

Publication number Publication date
ES444398A1 (en) 1977-12-01
AU6230273A (en) 1975-05-08
IE40043B1 (en) 1979-02-28
CH593930A5 (en) 1977-12-30
ES456279A1 (en) 1978-11-01
SE417957B (en) 1981-04-27
PH13261A (en) 1980-02-25
FR2291200B1 (en) 1979-01-05
NO743616L (en) 1974-05-09
IN139265B (en) 1976-05-29
JPS5714347B2 (en) 1982-03-24
NL7315307A (en) 1974-05-10
DE2355731A1 (en) 1974-05-22
DK143499C (en) 1982-01-11
JPS49133357A (en) 1974-12-21
PH13320A (en) 1980-03-13
ES420386A1 (en) 1976-07-01
DE2355731B2 (en) 1980-04-30
NO143663B (en) 1980-12-15
FI58912B (en) 1981-01-30
NO143663C (en) 1981-03-25
CA1033727A (en) 1978-06-27
FR2205338A1 (en) 1974-05-31
NO144385B (en) 1981-05-11
FR2291200A1 (en) 1976-06-11
SU704456A3 (en) 1979-12-15
SE7612261L (en) 1976-11-03
BE807046A (en) 1974-05-08
IL43571A0 (en) 1974-03-14
IL50310A (en) 1977-08-31
GB1456838A (en) 1976-11-24
FR2286147B1 (en) 1978-09-22
FI58912C (en) 1981-05-11
DE2355731C3 (en) 1981-01-15
ZA738595B (en) 1974-09-25
FR2286147A1 (en) 1976-04-23
AT345999B (en) 1978-10-10
SE412229B (en) 1980-02-25
IL43571A (en) 1977-08-31
FR2205338B1 (en) 1978-07-13
DK143499B (en) 1981-08-31
SU667131A3 (en) 1979-06-05
SE7701523L (en) 1977-02-10
SE7612262L (en) 1976-11-03
IE40043L (en) 1974-05-08
ATA941073A (en) 1978-02-15

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