NO136049C - Fremgangsm}te til fremstilling av 16beta-metyl-9alfa-fluor-11beta,17alfa-21-trihydroksy-1,4-pregnadien-3,20-dion samt dets 21-acylater. - Google Patents

Fremgangsm}te til fremstilling av 16beta-metyl-9alfa-fluor-11beta,17alfa-21-trihydroksy-1,4-pregnadien-3,20-dion samt dets 21-acylater.

Info

Publication number
NO136049C
NO136049C NO4780/70A NO478070A NO136049C NO 136049 C NO136049 C NO 136049C NO 4780/70 A NO4780/70 A NO 4780/70A NO 478070 A NO478070 A NO 478070A NO 136049 C NO136049 C NO 136049C
Authority
NO
Norway
Prior art keywords
9alfa
17alfa
16beta
11beta
pregnadiene
Prior art date
Application number
NO4780/70A
Other languages
English (en)
Norwegian (no)
Other versions
NO136049B (xx
Inventor
Ivan Villax
Original Assignee
Ivan Villax
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivan Villax filed Critical Ivan Villax
Publication of NO136049B publication Critical patent/NO136049B/no
Publication of NO136049C publication Critical patent/NO136049C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Table Devices Or Equipment (AREA)
NO4780/70A 1969-12-13 1970-12-11 Fremgangsm}te til fremstilling av 16beta-metyl-9alfa-fluor-11beta,17alfa-21-trihydroksy-1,4-pregnadien-3,20-dion samt dets 21-acylater. NO136049C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT5292369 1969-12-13

Publications (2)

Publication Number Publication Date
NO136049B NO136049B (xx) 1977-04-04
NO136049C true NO136049C (no) 1977-07-13

Family

ID=20081704

Family Applications (1)

Application Number Title Priority Date Filing Date
NO4780/70A NO136049C (no) 1969-12-13 1970-12-11 Fremgangsm}te til fremstilling av 16beta-metyl-9alfa-fluor-11beta,17alfa-21-trihydroksy-1,4-pregnadien-3,20-dion samt dets 21-acylater.

Country Status (15)

Country Link
US (1) US3792046A (xx)
JP (3) JPS508080B1 (xx)
AT (1) AT304774B (xx)
BE (1) BE760236A (xx)
CA (1) CA932321A (xx)
CH (1) CH551395A (xx)
DE (1) DE2059050A1 (xx)
DK (1) DK130991B (xx)
ES (1) ES386385A1 (xx)
FR (1) FR2081356B1 (xx)
GB (1) GB1328998A (xx)
IL (3) IL49763A (xx)
NL (1) NL166694C (xx)
NO (1) NO136049C (xx)
ZA (1) ZA708393B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58212359A (ja) * 1982-05-25 1983-12-10 マグネツト・モ−トル・ゲゼルシヤフト・フユア・マグネツトモ−トリツシエ・テクニ−ク・ミツト・ベシユレンクテル・ハフツンク 回転電気機械
JPS6261175U (xx) * 1985-10-02 1987-04-16
JPS62135570U (xx) * 1986-02-19 1987-08-26
EP1399464A1 (en) * 2001-06-18 2004-03-24 PHARMACIA & UPJOHN COMPANY Process to prepare 11beta, 17alpha, 21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-acetate
US20040006240A1 (en) * 2001-06-18 2004-01-08 Pearlman Bruce Allen Process to prepare 11beta,17alpha ,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-acetate
CN101555268B (zh) * 2009-05-21 2011-11-30 广西万德药业股份有限公司 一种糖皮质激素类9，11环氧物中间体制备方法
CN102304163A (zh) * 2011-07-11 2012-01-04 浙江仙居仙乐药业有限公司 一种倍他米松上氟合成方法
CN104945464B (zh) * 2015-04-17 2016-10-26 浙江仙居仙乐药业有限公司 一种倍他米松环氧水解物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1274397A (fr) * 1958-12-16 1961-10-27 Chimiotherapie Lab Franc Procédé de préparation de dérivés 9alpha-fluoro 16alpha-méthyl delta1, 4-pregnadiènes
FR1243528A (fr) * 1959-08-05 1960-10-14 Chimiotherapie Lab Franc Procédé d'acétoxylation de stéroïdes en 21 par l'intermédiaire de dérivés diiodés

Also Published As

Publication number Publication date
DK130991B (da) 1975-05-12
NL166694C (nl) 1981-09-15
IL35823A0 (en) 1971-02-25
IL49763A0 (en) 1976-08-31
AT304774B (de) 1973-01-25
IL35823A (en) 1977-08-31
NL166694B (nl) 1981-04-15
JPS5721279B1 (xx) 1982-05-06
GB1328998A (en) 1973-09-05
ZA708393B (en) 1972-07-26
NO136049B (xx) 1977-04-04
FR2081356B1 (xx) 1976-09-17
CA932321A (en) 1973-08-21
JPS5721280B1 (xx) 1982-05-06
IL49763A (en) 1977-08-31
US3792046A (en) 1974-02-12
DK130991C (xx) 1975-12-08
NL7017904A (xx) 1971-06-15
JPS508080B1 (xx) 1975-04-01
FR2081356A1 (xx) 1971-12-03
ES386385A1 (es) 1973-03-16
CH551395A (de) 1974-07-15
DE2059050A1 (de) 1972-04-06
BE760236A (fr) 1971-05-17

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