NO124265B - - Google Patents
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- Publication number
- NO124265B NO124265B NO163009A NO16300966A NO124265B NO 124265 B NO124265 B NO 124265B NO 163009 A NO163009 A NO 163009A NO 16300966 A NO16300966 A NO 16300966A NO 124265 B NO124265 B NO 124265B
- Authority
- NO
- Norway
- Prior art keywords
- cells
- infectious hepatitis
- hepatitis virus
- virus
- live
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 claims description 49
- 241000700605 Viruses Species 0.000 claims description 43
- 208000037319 Hepatitis infectious Diseases 0.000 claims description 33
- 208000005252 hepatitis A Diseases 0.000 claims description 33
- 210000002966 serum Anatomy 0.000 claims description 33
- 239000007788 liquid Substances 0.000 claims description 27
- 210000001519 tissue Anatomy 0.000 claims description 22
- 229960005486 vaccine Drugs 0.000 claims description 19
- 239000012531 culture fluid Substances 0.000 claims description 15
- 238000004519 manufacturing process Methods 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 8
- 210000004369 blood Anatomy 0.000 claims description 7
- 239000008280 blood Substances 0.000 claims description 7
- 241000282693 Cercopithecidae Species 0.000 claims description 6
- VEZXCJBBBCKRPI-UHFFFAOYSA-N beta-propiolactone Chemical compound O=C1CCO1 VEZXCJBBBCKRPI-UHFFFAOYSA-N 0.000 claims description 6
- 238000011282 treatment Methods 0.000 claims description 6
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 5
- 239000000427 antigen Substances 0.000 claims description 5
- 102000036639 antigens Human genes 0.000 claims description 5
- 108091007433 antigens Proteins 0.000 claims description 5
- 241001465754 Metazoa Species 0.000 claims description 4
- 210000002308 embryonic cell Anatomy 0.000 claims description 4
- 239000002356 single layer Substances 0.000 claims description 4
- 108010077544 Chromatin Proteins 0.000 claims description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 210000003483 chromatin Anatomy 0.000 claims description 3
- 230000000694 effects Effects 0.000 claims description 3
- 239000011343 solid material Substances 0.000 claims description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 2
- 230000002411 adverse Effects 0.000 claims description 2
- 239000000460 chlorine Substances 0.000 claims description 2
- 229910052801 chlorine Inorganic materials 0.000 claims description 2
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 claims description 2
- 239000010409 thin film Substances 0.000 claims description 2
- 239000002609 medium Substances 0.000 description 25
- 239000000725 suspension Substances 0.000 description 12
- 208000015181 infectious disease Diseases 0.000 description 11
- 241000282414 Homo sapiens Species 0.000 description 10
- 238000011534 incubation Methods 0.000 description 9
- 230000002458 infectious effect Effects 0.000 description 8
- 239000010410 layer Substances 0.000 description 8
- 238000011081 inoculation Methods 0.000 description 7
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 208000006454 hepatitis Diseases 0.000 description 6
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 5
- 230000000890 antigenic effect Effects 0.000 description 5
- 231100000283 hepatitis Toxicity 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 239000012981 Hank's balanced salt solution Substances 0.000 description 4
- 239000003139 biocide Substances 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 238000012423 maintenance Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 230000000120 cytopathologic effect Effects 0.000 description 3
- 238000010790 dilution Methods 0.000 description 3
- 239000012895 dilution Substances 0.000 description 3
- 230000002349 favourable effect Effects 0.000 description 3
- 230000003053 immunization Effects 0.000 description 3
- 210000001161 mammalian embryo Anatomy 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 210000001550 testis Anatomy 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 241000700199 Cavia porcellus Species 0.000 description 2
- 241000282412 Homo Species 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 230000010261 cell growth Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 210000003754 fetus Anatomy 0.000 description 2
- 208000002672 hepatitis B Diseases 0.000 description 2
- 239000012499 inoculation medium Substances 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000003612 virological effect Effects 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 206010014979 Epidemic typhus Diseases 0.000 description 1
- 241000282579 Pan Species 0.000 description 1
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
- 241000606651 Rickettsiales Species 0.000 description 1
- 241000283984 Rodentia Species 0.000 description 1
- 241000287231 Serinus Species 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000011888 autopsy Methods 0.000 description 1
- 239000003855 balanced salt solution Substances 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 210000003837 chick embryo Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000012364 cultivation method Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 208000028104 epidemic louse-borne typhus Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012737 fresh medium Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 229910052573 porcelain Inorganic materials 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000003104 tissue culture media Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 238000005199 ultracentrifugation Methods 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F214/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen
- C08F214/02—Monomers containing chlorine
- C08F214/04—Monomers containing two carbon atoms
- C08F214/08—Vinylidene chloride
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S526/00—Synthetic resins or natural rubbers -- part of the class 520 series
- Y10S526/915—Redox catalyst
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Paper (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polymerisation Methods In General (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH689765A CH449264A (de) | 1965-05-18 | 1965-05-18 | Verfahren zur Herstellung neuer Copolymerisate des Vinylidenchlorides |
Publications (1)
Publication Number | Publication Date |
---|---|
NO124265B true NO124265B (xx) | 1972-03-27 |
Family
ID=4316773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO163009A NO124265B (xx) | 1965-05-18 | 1966-05-13 |
Country Status (9)
Country | Link |
---|---|
US (1) | US3449302A (xx) |
AT (1) | AT267172B (xx) |
BE (1) | BE681150A (xx) |
CH (1) | CH449264A (xx) |
DE (1) | DE1595413A1 (xx) |
GB (1) | GB1082037A (xx) |
NL (1) | NL6606757A (xx) |
NO (1) | NO124265B (xx) |
SE (1) | SE328697B (xx) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3850726A (en) * | 1969-04-28 | 1974-11-26 | Staley Mfg Co A E | Vinylidene chloride copolymer |
US3946139A (en) * | 1974-01-17 | 1976-03-23 | W. R. Grace & Co. | Vinylidene chloride copolymer latexes |
JPS6053055B2 (ja) * | 1980-02-15 | 1985-11-22 | 旭化成株式会社 | 塩化ビニリデン系樹脂水分散体組成 |
US4446273A (en) * | 1981-06-03 | 1984-05-01 | The Dow Chemical Company | Aqueous dispersions of vinylidene chloride resins |
US5912297A (en) * | 1983-07-25 | 1999-06-15 | Henkel Corporation | Internally stabilized vinylidene chloride resin in autodeposition |
US6224947B1 (en) | 1983-07-25 | 2001-05-01 | Henkel Corporation | Process for forming a resinous coating from an autodepositing composition which includes internally stabilized vinylidene chloride copolymer |
KR100557553B1 (ko) * | 2001-06-29 | 2006-03-03 | 주식회사 하이닉스반도체 | 포토레지스트 단량체, 그의 중합체 및 이를 함유하는포토레지스트 조성물 |
US7165676B2 (en) * | 2002-04-19 | 2007-01-23 | Smurfit-Stone Container Enterprises, Inc. | Heat seal blister package having improved moisture vapor transmission barrier and method for forming same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL109430C (xx) * | 1959-03-13 | |||
US3235535A (en) * | 1962-04-10 | 1966-02-15 | Union Carbide Corp | Aromatic vinyl sulfones and polymers thereof |
US3192231A (en) * | 1962-09-19 | 1965-06-29 | American Cyanamid Co | Unsaturated substituted cyclic sulfones and process for preparing the same |
US3310535A (en) * | 1963-06-24 | 1967-03-21 | Monsanto Co | Acrylonitrile tetrapolymers, process for preparing same and fibers thereof |
-
1965
- 1965-05-18 CH CH689765A patent/CH449264A/de unknown
-
1966
- 1966-05-03 US US547168A patent/US3449302A/en not_active Expired - Lifetime
- 1966-05-10 DE DE19661595413 patent/DE1595413A1/de active Pending
- 1966-05-10 GB GB20729/66A patent/GB1082037A/en not_active Expired
- 1966-05-13 NO NO163009A patent/NO124265B/no unknown
- 1966-05-16 SE SE06709/66A patent/SE328697B/xx unknown
- 1966-05-17 NL NL6606757A patent/NL6606757A/xx unknown
- 1966-05-17 BE BE681150D patent/BE681150A/xx unknown
- 1966-05-17 AT AT466766A patent/AT267172B/de active
Also Published As
Publication number | Publication date |
---|---|
DE1595413A1 (de) | 1970-03-19 |
BE681150A (xx) | 1966-11-17 |
AT267172B (de) | 1968-12-10 |
US3449302A (en) | 1969-06-10 |
NL6606757A (xx) | 1966-11-21 |
GB1082037A (en) | 1967-09-06 |
CH449264A (de) | 1967-12-31 |
SE328697B (xx) | 1970-09-21 |
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