NL8703075A - Acridiniumverbindingen als chemiluminescentie-merkstof. - Google Patents

Acridiniumverbindingen als chemiluminescentie-merkstof. Download PDF

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Publication number
NL8703075A
NL8703075A NL8703075A NL8703075A NL8703075A NL 8703075 A NL8703075 A NL 8703075A NL 8703075 A NL8703075 A NL 8703075A NL 8703075 A NL8703075 A NL 8703075A NL 8703075 A NL8703075 A NL 8703075A
Authority
NL
Netherlands
Prior art keywords
group
chemiluminescence
compound according
acridinium
compounds
Prior art date
Application number
NL8703075A
Other languages
English (en)
Dutch (nl)
Original Assignee
Nederlanden Staat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlanden Staat filed Critical Nederlanden Staat
Priority to NL8703075A priority Critical patent/NL8703075A/nl
Priority to DE3851216T priority patent/DE3851216T2/de
Priority to AT88202802T priority patent/ATE110366T1/de
Priority to ES88202802T priority patent/ES2056907T3/es
Priority to EP88202802A priority patent/EP0324202B1/fr
Priority to CA000586045A priority patent/CA1334418C/fr
Priority to JP63318327A priority patent/JPH0819106B2/ja
Publication of NL8703075A publication Critical patent/NL8703075A/nl
Priority to US07/719,656 priority patent/US5521103A/en
Priority to US08/478,125 priority patent/US6018047A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C09K11/07—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials having chemically interreactive components, e.g. reactive chemiluminescent compositions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
NL8703075A 1987-12-18 1987-12-18 Acridiniumverbindingen als chemiluminescentie-merkstof. NL8703075A (nl)

Priority Applications (9)

Application Number Priority Date Filing Date Title
NL8703075A NL8703075A (nl) 1987-12-18 1987-12-18 Acridiniumverbindingen als chemiluminescentie-merkstof.
DE3851216T DE3851216T2 (de) 1987-12-18 1988-12-07 Akridinium-Verbindungen als chemilumineszierende Bezeichnungen.
AT88202802T ATE110366T1 (de) 1987-12-18 1988-12-07 Akridinium-verbindungen als chemilumineszierende bezeichnungen.
ES88202802T ES2056907T3 (es) 1987-12-18 1988-12-07 Compuestos de acridinio que pueden utilizarse como marcadores quimioluminogenos.
EP88202802A EP0324202B1 (fr) 1987-12-18 1988-12-07 Dérivés d'acridinium comme marques chémioluminescentes
CA000586045A CA1334418C (fr) 1987-12-18 1988-12-15 Composes de type acridinium utilises comme marqueurs chimioluminescents
JP63318327A JPH0819106B2 (ja) 1987-12-18 1988-12-16 化学ルミノゲン標識としてのアクリジニウム化合物
US07/719,656 US5521103A (en) 1987-12-18 1991-06-24 Acridinium compounds as chemiluminogenic label
US08/478,125 US6018047A (en) 1987-12-18 1995-06-07 Acridinium compounds as chemiluminogenic label

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8703075A NL8703075A (nl) 1987-12-18 1987-12-18 Acridiniumverbindingen als chemiluminescentie-merkstof.
NL8703075 1987-12-18

Publications (1)

Publication Number Publication Date
NL8703075A true NL8703075A (nl) 1989-07-17

Family

ID=19851117

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8703075A NL8703075A (nl) 1987-12-18 1987-12-18 Acridiniumverbindingen als chemiluminescentie-merkstof.

Country Status (8)

Country Link
US (2) US5521103A (fr)
EP (1) EP0324202B1 (fr)
JP (1) JPH0819106B2 (fr)
AT (1) ATE110366T1 (fr)
CA (1) CA1334418C (fr)
DE (1) DE3851216T2 (fr)
ES (1) ES2056907T3 (fr)
NL (1) NL8703075A (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110932A (en) * 1986-10-06 1992-05-05 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
EP0273115B1 (fr) * 1986-10-22 1994-09-07 Abbott Laboratories Sels d'acridines et de phénantridines chimiluminescents
US5338847A (en) * 1987-12-31 1994-08-16 London Diagnostics, Inc. Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation
US5284951A (en) * 1987-12-31 1994-02-08 London Diagnostics, Inc. Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom
US5321136A (en) * 1987-12-31 1994-06-14 London Diagnostics, Inc. Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom
NZ227506A (en) † 1987-12-31 1992-06-25 London Diagnostics Inc Specific binding assays using chemiluminescent compounds
US5227489A (en) * 1988-08-01 1993-07-13 Ciba Corning Diagnostics Corp. Stable hydrophilic acridinium esters suitable for liposome encapsulation
US5663074A (en) * 1988-09-26 1997-09-02 Chiron Diagnostics Corporation Nucleophilic polysubstituted aryl acridinium ester conjugates and syntheses thereof
US5241070A (en) * 1988-09-26 1993-08-31 Ciba Corning Diagnostics Corp. Nucleophilic polysubstituted aryl acridinium esters and uses thereof
US5340716A (en) * 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
JPH07509245A (ja) * 1992-07-20 1995-10-12 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 新規化学発光化合物およびその使用方法
US6002000A (en) * 1992-07-20 1999-12-14 Dade Behring Marburg Gmbh Chemiluminescent compounds and methods of use
EP0653066B1 (fr) * 1992-07-31 1998-01-28 BEHRINGWERKE Aktiengesellschaft Matrices chimioluminescentes photoactivables
JP3584379B2 (ja) * 1993-02-04 2004-11-04 持田製薬株式会社 アクリジニウム化合物およびアクリジニウム化合物複合体
US5593845A (en) * 1993-05-17 1997-01-14 Lumigen, Inc. Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
EP0761652A1 (fr) * 1995-08-01 1997-03-12 Mochida Pharmaceutical Co., Ltd. Dérivés d'acridinium à plusieurs groupes luminescents et groupes liants et leur conjugués
US5800999A (en) * 1996-12-16 1998-09-01 Tropix, Inc. Dioxetane-precursor-labeled probes and detection assays employing the same
US6165800A (en) * 1997-05-30 2000-12-26 Bayer Corporation Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
US6017769A (en) * 1998-06-17 2000-01-25 Lumigen, Inc. Non-enzymatic methods of generating chemiluminescence from acridan alkenes
JP4672144B2 (ja) 1998-08-11 2011-04-20 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド 近赤外化学発光性アクリジニウム化合物およびその使用。
US6673560B1 (en) 1998-11-25 2004-01-06 Bayer Corporation Measurement of hydride using chemiluminescent acridinium compounds and applications thereof
KR100399370B1 (ko) * 2000-12-22 2003-09-26 김병효 아크리디늄 화합물 및 이를 이용한 화학발광 조성물
US7101683B2 (en) 2001-06-26 2006-09-05 Abbott Laboratories Methods for the simultaneous detection of HCV antigens and HCV antibodies
US6723851B2 (en) 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
US7319041B2 (en) * 2002-09-27 2008-01-15 Siemens Medical Solutions Diagnostic Applications of acridinium compounds and derivatives in homogeneous assays
US7309615B2 (en) * 2002-09-27 2007-12-18 Siemens Medical Solutions Diagnostic High quantum yield acridinium compounds and their uses in improving assay sensitivity
JP2006526137A (ja) * 2003-05-28 2006-11-16 ジーイー・ヘルスケア・ユーケイ・リミテッド 内部標準の存在下で色素を標識することによる閉じた膜構造上の細胞表面タンパク質の示差分析
GB0320236D0 (en) * 2003-08-29 2003-10-01 Molecular Light Tech Res Ltd Chemiluminescent compounds
US20060205094A1 (en) * 2005-03-14 2006-09-14 Lumigen, Inc. Methods using novel chemiluminescent labels
US7682839B2 (en) * 2005-03-14 2010-03-23 Lumigen, Inc. Methods using novel chemiluminescent labels
US20070151234A1 (en) * 2005-12-30 2007-07-05 Lampkin Charles B Iii Electricity produced by sustained air pressure
US20210040556A1 (en) * 2019-08-07 2021-02-11 Bgi Shenzhen Co., Ltd. Acridinium ester-containing compounds and methods of using the same for chemiluminescence-based one-color sequencing

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2645594A (en) * 1948-10-19 1953-07-14 Abbott Lab Antiseptic acridane compounds
NL6515469A (fr) * 1965-01-22 1966-07-25
US3431264A (en) * 1965-11-05 1969-03-04 American Cyanamid Co 9-cyanoacridans and process for their production
US3615416A (en) * 1969-06-05 1971-10-26 Eastman Kodak Co 9 10-substituted acridines as sensitizers in electrophotographic systems
GB1461877A (en) * 1974-02-12 1977-01-19 Wellcome Found Assay method utilizing chemiluminescence
GB2112779B (en) * 1981-12-11 1986-10-15 Welsh Nat School Med Aryl acridinium esters as luminescent labelling materials
DE3379179D1 (en) * 1982-09-10 1989-03-16 Welsh Nat School Med Immunological procedure for quantifying substances
JP2509574B2 (ja) * 1985-08-15 1996-06-19 アモコ・コーポレーション 標識付けした核酸
JPS6261969A (ja) * 1985-09-06 1987-03-18 アモコ・コーポレーション アクリジニウムエステルの合成法
US4745181A (en) * 1986-10-06 1988-05-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
EP0273115B1 (fr) * 1986-10-22 1994-09-07 Abbott Laboratories Sels d'acridines et de phénantridines chimiluminescents

Also Published As

Publication number Publication date
ATE110366T1 (de) 1994-09-15
US5521103A (en) 1996-05-28
JPH01199949A (ja) 1989-08-11
DE3851216T2 (de) 1995-02-16
US6018047A (en) 2000-01-25
JPH0819106B2 (ja) 1996-02-28
EP0324202B1 (fr) 1994-08-24
ES2056907T3 (es) 1994-10-16
CA1334418C (fr) 1995-02-14
DE3851216D1 (de) 1994-09-29
EP0324202A1 (fr) 1989-07-19

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BV The patent application has lapsed