NL7804136A - 4-gesubstitueerde piperazine-1-(n-aryl-n'-cyano)-carbo- ximidamiden. - Google Patents

4-gesubstitueerde piperazine-1-(n-aryl-n'-cyano)-carbo- ximidamiden.

Info

Publication number
NL7804136A
NL7804136A NL7804136A NL7804136A NL7804136A NL 7804136 A NL7804136 A NL 7804136A NL 7804136 A NL7804136 A NL 7804136A NL 7804136 A NL7804136 A NL 7804136A NL 7804136 A NL7804136 A NL 7804136A
Authority
NL
Netherlands
Prior art keywords
carboximidamides
cyano
aryl
substituted piperazine
piperazine
Prior art date
Application number
NL7804136A
Other languages
English (en)
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Publication of NL7804136A publication Critical patent/NL7804136A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
NL7804136A 1977-10-25 1978-04-18 4-gesubstitueerde piperazine-1-(n-aryl-n'-cyano)-carbo- ximidamiden. NL7804136A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI773167A FI56836C (fi) 1977-10-25 1977-10-25 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner

Publications (1)

Publication Number Publication Date
NL7804136A true NL7804136A (nl) 1979-04-27

Family

ID=8511168

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7804136A NL7804136A (nl) 1977-10-25 1978-04-18 4-gesubstitueerde piperazine-1-(n-aryl-n'-cyano)-carbo- ximidamiden.

Country Status (6)

Country Link
JP (1) JPS55341A (nl)
ES (1) ES474468A1 (nl)
FI (1) FI56836C (nl)
NL (1) NL7804136A (nl)
PT (1) PT68690A (nl)
ZA (1) ZA785321B (nl)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2231571A (en) * 1989-04-21 1990-11-21 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of quinazoline derivatives
WO2004002983A2 (en) * 2002-06-28 2004-01-08 Euro-Celtique, S.A. Therapeutic piperazine derivatives useful for treating pain
WO2008122787A1 (en) * 2007-04-05 2008-10-16 Evotec Ag Piperazine compounds for the inhibition of haematopoietic prostaglandin d synthase
US7696207B2 (en) 2002-07-26 2010-04-13 Purdue Pharma L.P. Therapeutic agents useful for treating pain

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6245667A (ja) * 1985-08-22 1987-02-27 Shin Etsu Chem Co Ltd 塗料組成物
US4889179A (en) * 1987-11-25 1989-12-26 J. R. Microwave, Inc. Two wire adaptive system for interconnecting a four wire thermostat and a four wire, heating/cooling system

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2231571A (en) * 1989-04-21 1990-11-21 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of quinazoline derivatives
GB2231571B (en) * 1989-04-21 1992-09-16 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of quinazoline derivatives
WO2004002983A2 (en) * 2002-06-28 2004-01-08 Euro-Celtique, S.A. Therapeutic piperazine derivatives useful for treating pain
WO2004002983A3 (en) * 2002-06-28 2004-03-18 Euro Celtique Sa Therapeutic piperazine derivatives useful for treating pain
US7279493B2 (en) 2002-06-28 2007-10-09 Euro-Celtique S.A. Therapeutic agents useful for treating pain
CN100457735C (zh) * 2002-06-28 2009-02-04 欧洲凯尔特公司 用于治疗疼痛的治疗剂
US7799786B2 (en) 2002-06-28 2010-09-21 Purdue Pharma L.P. Therapeutic agents useful for treating pain
US7696207B2 (en) 2002-07-26 2010-04-13 Purdue Pharma L.P. Therapeutic agents useful for treating pain
WO2008122787A1 (en) * 2007-04-05 2008-10-16 Evotec Ag Piperazine compounds for the inhibition of haematopoietic prostaglandin d synthase

Also Published As

Publication number Publication date
ZA785321B (en) 1979-10-31
PT68690A (en) 1978-11-01
JPS55341A (en) 1980-01-05
FI56836B (fi) 1979-12-31
FI773167A (fi) 1979-04-26
FI56836C (fi) 1980-04-10
ES474468A1 (es) 1979-10-16

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Legal Events

Date Code Title Description
A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
BT A document has been added to the application laid open to public inspection
BV The patent application has lapsed