FI56836B - 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner - Google Patents

4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner

Info

Publication number
FI56836B
FI56836B FI773167A FI773167A FI56836B FI 56836 B FI56836 B FI 56836B FI 773167 A FI773167 A FI 773167A FI 773167 A FI773167 A FI 773167A FI 56836 B FI56836 B FI 56836B
Authority
FI
Finland
Prior art keywords
kinazoliner
carboximidamider
trimetoxy
dimetoxy
substituerade
Prior art date
Application number
FI773167A
Other languages
English (en)
Other versions
FI773167A (fi
FI56836C (fi
Inventor
Heinrich Thaler
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Priority to FI773167A priority Critical patent/FI56836C/fi
Priority to NL7804136A priority patent/NL7804136A/xx
Priority to ZA00785321A priority patent/ZA785321B/xx
Priority to JP12996078A priority patent/JPS55341A/ja
Priority to PT68690A priority patent/PT68690A/pt
Priority to ES474468A priority patent/ES474468A1/es
Publication of FI773167A publication Critical patent/FI773167A/fi
Publication of FI56836B publication Critical patent/FI56836B/fi
Application granted granted Critical
Publication of FI56836C publication Critical patent/FI56836C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
FI773167A 1977-10-25 1977-10-25 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner FI56836C (fi)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FI773167A FI56836C (fi) 1977-10-25 1977-10-25 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner
NL7804136A NL7804136A (nl) 1977-10-25 1978-04-18 4-gesubstitueerde piperazine-1-(n-aryl-n'-cyano)-carbo- ximidamiden.
ZA00785321A ZA785321B (en) 1977-10-25 1978-09-19 4-substituted piperazine-1-(n-aryl-n'-cyano)-carboximidamides
JP12996078A JPS55341A (en) 1977-10-25 1978-10-20 44substituted piperazinee11*nnarylln**cyano** carboxyimide amide
PT68690A PT68690A (en) 1977-10-25 1978-10-23 Process for preparing 4-substituted piperazine-1-(n-aryl-n'-ciano)-carboximidamides
ES474468A ES474468A1 (es) 1977-10-25 1978-10-24 Procedimiento para la preparacion de piperacina -1-(n-aril- n'-cianocarboximidamidas 4-substituidas

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI773167A FI56836C (fi) 1977-10-25 1977-10-25 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner
FI773167 1977-10-25

Publications (3)

Publication Number Publication Date
FI773167A FI773167A (fi) 1979-04-26
FI56836B true FI56836B (fi) 1979-12-31
FI56836C FI56836C (fi) 1980-04-10

Family

ID=8511168

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773167A FI56836C (fi) 1977-10-25 1977-10-25 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner

Country Status (6)

Country Link
JP (1) JPS55341A (fi)
ES (1) ES474468A1 (fi)
FI (1) FI56836C (fi)
NL (1) NL7804136A (fi)
PT (1) PT68690A (fi)
ZA (1) ZA785321B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6245667A (ja) * 1985-08-22 1987-02-27 Shin Etsu Chem Co Ltd 塗料組成物
US4889179A (en) * 1987-11-25 1989-12-26 J. R. Microwave, Inc. Two wire adaptive system for interconnecting a four wire thermostat and a four wire, heating/cooling system
YU70890A (en) * 1989-04-21 1992-05-28 Egyt Gyogyszervegyeszeti Gyar Process for obtaining quinazoline derivatives
WO2004002983A2 (en) * 2002-06-28 2004-01-08 Euro-Celtique, S.A. Therapeutic piperazine derivatives useful for treating pain
US7262194B2 (en) 2002-07-26 2007-08-28 Euro-Celtique S.A. Therapeutic agents useful for treating pain
GB0706793D0 (en) * 2007-04-05 2007-05-16 Evotec Ag Compounds

Also Published As

Publication number Publication date
ZA785321B (en) 1979-10-31
PT68690A (en) 1978-11-01
JPS55341A (en) 1980-01-05
FI773167A (fi) 1979-04-26
NL7804136A (nl) 1979-04-27
FI56836C (fi) 1980-04-10
ES474468A1 (es) 1979-10-16

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: ORION-YHTYMAE OY FERMION