NL7711934A - Arylamiden. - Google Patents

Arylamiden.

Info

Publication number
NL7711934A
NL7711934A NL7711934A NL7711934A NL7711934A NL 7711934 A NL7711934 A NL 7711934A NL 7711934 A NL7711934 A NL 7711934A NL 7711934 A NL7711934 A NL 7711934A NL 7711934 A NL7711934 A NL 7711934A
Authority
NL
Netherlands
Prior art keywords
arylamids
Prior art date
Application number
NL7711934A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NL7711934A publication Critical patent/NL7711934A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Furan Compounds (AREA)
NL7711934A 1976-11-12 1977-10-31 Arylamiden. NL7711934A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/741,467 US4098904A (en) 1976-11-12 1976-11-12 Analgesic n-(2-aminocycloaliphatic)benzamides

Publications (1)

Publication Number Publication Date
NL7711934A true NL7711934A (nl) 1978-05-17

Family

ID=24980833

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7711934A NL7711934A (nl) 1976-11-12 1977-10-31 Arylamiden.

Country Status (12)

Country Link
US (4) US4098904A (nl)
JP (1) JPS5363352A (nl)
AU (1) AU515054B2 (nl)
BE (1) BE860727A (nl)
CA (1) CA1072558A (nl)
CH (1) CH643817A5 (nl)
DE (1) DE2749984A1 (nl)
ES (1) ES463877A1 (nl)
FR (1) FR2370722A1 (nl)
GB (1) GB1588460A (nl)
NL (1) NL7711934A (nl)
ZA (1) ZA776240B (nl)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179501A (en) * 1976-11-12 1979-12-18 The Upjohn Company Analgesic N-(2-aminocycloaliphatic)azidobenzamides
US4217362A (en) * 1976-11-30 1980-08-12 The Upjohn Company Anilide derivatives as antidepressants
US4212878A (en) * 1978-01-26 1980-07-15 The Upjohn Company Phenylacetamide derivative analgesics
US4346101A (en) * 1980-12-08 1982-08-24 The Upjohn Company Benzamide derivative analgesics
US4460600A (en) * 1981-04-09 1984-07-17 The Upjohn Company Adjacently substituted ketal derivatives of cycloalkane-amide analgesics
US4360531A (en) * 1981-04-09 1982-11-23 The Upjohn Company Substituted cycloalkanes
US4466977A (en) * 1981-04-09 1984-08-21 The Upjohn Company N-[2-Amino(oxy- or thia- group-substituted-cycloaliphatic)]benzeneacetamides and -benzamide analgesics
US4359476A (en) * 1981-04-09 1982-11-16 The Upjohn Company Adjacently substituted cycloalkane-amide analgesics
US4540690A (en) * 1982-02-09 1985-09-10 The Upjohn Company 2-(Phenylmethylene)cycloalkylamines and -azetidines
US4508911A (en) * 1982-06-21 1985-04-02 The Upjohn Company Amine intermediates for analgesic compounds
US4652559A (en) * 1982-08-16 1987-03-24 The Upjohn Company 2-(Phenylmethylene)cycloalkyl-azetidines
AT376669B (de) * 1982-11-26 1984-12-27 Laevosan Gmbh & Co Kg Verfahren zur herstellung neuer thienylessigsaeureamid-derivate und pharmazeutisch vertraeglicher saeureadditionssalze davon
US4598088A (en) * 1983-05-18 1986-07-01 The Upjohn Company 2-pyrrolyl-cycloalkyl-amide analgesics
ZA842753B (en) * 1983-05-18 1984-11-28 Upjohn Co 2-dihydropyrrolyl-cycloalkyl-amide analgesics
US4560767A (en) * 1983-06-17 1985-12-24 The Upjohn Company N-(2-amino-cycloalkenyl)benzeneacetamide and -benzamide analgesics and tritiated kappa agonists therefrom
US4579863A (en) * 1983-12-06 1986-04-01 Warner-Lambert Company Substituted trans-1,2-diaminocyclohexyl amide compounds
US4598087A (en) * 1983-12-06 1986-07-01 Warner-Lambert Company Substituted trans-1,2-diaminocyclohexyl amide compounds
US4588591A (en) * 1984-05-25 1986-05-13 The Upjohn Company Analgesic 2-oxa-spirocyclic compounds
US4632935A (en) * 1984-05-30 1986-12-30 The Upjohn Company Omega-(hydroxy-, ether and ester)-alkyl-2-amino-cycloalkyl- and cycloalkenyl amides as analgesics
US4677122A (en) * 1984-11-13 1987-06-30 Warner-Lambert Company Substituted trans-1,2-diaminocyclohexyl amide compounds
US4737493A (en) * 1985-07-01 1988-04-12 Warner-Lambert Company 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro(4,5)decanes as analgesic agents
US4663343A (en) * 1985-07-19 1987-05-05 Warner-Lambert Company Substituted naphthalenyloxy-1,2-diaminocyclohexyl amide compounds
EP0222533A1 (en) * 1985-10-25 1987-05-20 The Upjohn Company Cis-N-[(2-aminocycloaliphatic)benzene acetamide and -benzamide anticonvulsants
US4663335A (en) * 1985-10-25 1987-05-05 The Upjohn Company Trans-(+)-2-(3,4-dichlorophenyl)-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]ac
US4801604A (en) * 1985-10-25 1989-01-31 The Upjohn Company Cis-N-(2-aminocycloaliphatic)benzamide anti-convulsants
FR2592879B1 (fr) * 1986-01-13 1988-04-29 Roussel Uclaf Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant
ZA876778B (en) * 1986-09-10 1989-05-30 Du Pont Benzo-fused cycloalkane and oxa-and thia-,cycloalkane trans-1,2-diamine derivatives
US4876269A (en) * 1986-09-10 1989-10-24 E. I. Du Pont De Nemours And Company Benoz-fused cycloalkane trans-1,2-diamine derivatives
US5010085A (en) * 1986-09-10 1991-04-23 E. I. Du Pont De Nemours And Company Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-diamine derivatives
FR2608598B1 (fr) * 1986-12-23 1989-04-14 Roussel Uclaf Nouveaux derives de l'indane, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant
US5051428A (en) * 1988-12-06 1991-09-24 Warner-Lambert Company 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics
FR2674849B1 (fr) * 1991-04-02 1994-12-23 Logeais Labor Jacques Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique.
US5475019A (en) * 1993-02-08 1995-12-12 East Carolina University Method of treating anxiety-related disorders with 2-aminocycloaliphatic amide compounds
US6239154B1 (en) 1996-03-08 2001-05-29 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
USRE38133E1 (en) * 1996-03-08 2003-06-03 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6303611B1 (en) 1996-03-08 2001-10-16 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US5763445A (en) * 1996-03-08 1998-06-09 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
US6750216B2 (en) * 1996-03-08 2004-06-15 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6057323A (en) * 1996-03-08 2000-05-02 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
US5688955A (en) * 1996-03-08 1997-11-18 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US5646151A (en) * 1996-03-08 1997-07-08 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
FR2800371B1 (fr) * 1999-10-29 2003-04-25 Rhodia Chimie Sa Nouveaux composes de type diamine mono- ou poly- fluore, sulfonyle ou carbonyle, leur procede de preparation et leur application en catalyse asymetrique
JP2003502296A (ja) * 1999-06-15 2003-01-21 ロディア・シミ スルホニルアミド及びカルボキサミド並びに不斉触媒作用におけるそれらの使用
FR2795070A1 (fr) * 1999-06-15 2000-12-22 Rhodia Chimie Sa Nouveaux composes de type diamine mono- ou poly- fluore, sulfonyle ou carbonyle, leur procede de preparation et leur application en catalyse asymetrique
CA2315815A1 (en) 2000-07-19 2002-01-19 Peter R. Ford Topical pain relief composition and carrier
EP1427696A1 (en) * 2001-09-13 2004-06-16 F. Hoffmann-La Roche Ag Ccr-3 receptor antagonists v
US6852713B2 (en) * 2003-04-16 2005-02-08 Adolor Corporation Lactam derivatives and methods of their use
US6992193B2 (en) 2003-06-10 2006-01-31 Adolor Corporation Sulfonylamino phenylacetamide derivatives and methods of their use
US7034051B2 (en) * 2003-08-28 2006-04-25 Adolor Corporation Fused bicyclic carboxamide derivatives and methods of their use
US7160902B2 (en) * 2003-11-14 2007-01-09 Adolor Corporation Amide derivatives and methods of their use
TW200808695A (en) * 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
US8080541B2 (en) 2009-08-27 2011-12-20 Hoffman-La Roche Inc. Carbocyclic GlyT-1 receptor antagonists
CN102531918B (zh) * 2012-01-18 2013-10-02 安阳工学院 一种对映纯对称反式二烷基环己胺的合成方法
CN102731316B (zh) * 2012-05-21 2014-04-16 南通市华峰化工有限责任公司 一种1，2-n，n`二甲基环己二胺的生产方法
CN106631815B (zh) * 2016-10-13 2018-10-09 上海瀚鸿科技股份有限公司 一种合成反式环己二胺的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499033A (en) * 1967-01-06 1970-03-03 Upjohn Co Ethers of alpha-phenyl-2-aminocycloalkanemethanols
US3373195A (en) * 1967-03-07 1968-03-12 Squibb & Sons Inc 2-substituted aminomethylcyclooctyl amides of alkyl substituted acetic acid
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines
US3647804A (en) * 1970-02-27 1972-03-07 Upjohn Co Cycloalkanecarboxamides
US3847982A (en) * 1970-07-15 1974-11-12 Upjohn Co Oxygenated n-benzoyl-n,2,3,3-tetramethyl-exo-2-norbornanamines
US3825595A (en) * 1971-03-12 1974-07-23 Univ Toledo N-cyclopentyl-n-2-hydroxyalkyl-ring-substituted benzamides
US3975443A (en) * 1972-06-06 1976-08-17 Allen & Hanburys Limited 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine
SE404186B (sv) * 1975-06-09 1978-09-25 Astra Laekemedel Ab Forfarande for framstellning av cyklopropanolderivat

Also Published As

Publication number Publication date
CA1072558A (en) 1980-02-26
US4153717A (en) 1979-05-08
GB1588460A (en) 1981-04-23
CH643817A5 (de) 1984-06-29
JPS5363352A (en) 1978-06-06
US4152459A (en) 1979-05-01
AU515054B2 (en) 1981-03-12
AU2984077A (en) 1979-04-26
ES463877A1 (es) 1978-12-16
US4148914A (en) 1979-04-10
DE2749984A1 (de) 1978-05-18
FR2370722B1 (nl) 1981-12-04
ZA776240B (en) 1978-07-26
FR2370722A1 (fr) 1978-06-09
BE860727A (fr) 1978-05-10
DE2749984C2 (nl) 1988-04-14
US4098904A (en) 1978-07-04
JPS6148494B2 (nl) 1986-10-24

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed