NL7609874A - Werkwijze ter bereiding van nieuwe aminoglyco- siden. - Google Patents

Werkwijze ter bereiding van nieuwe aminoglyco- siden.

Info

Publication number
NL7609874A
NL7609874A NL7609874A NL7609874A NL7609874A NL 7609874 A NL7609874 A NL 7609874A NL 7609874 A NL7609874 A NL 7609874A NL 7609874 A NL7609874 A NL 7609874A NL 7609874 A NL7609874 A NL 7609874A
Authority
NL
Netherlands
Prior art keywords
preparing new
aminoglyco
sides
aminoglyco sides
preparing
Prior art date
Application number
NL7609874A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NL7609874A publication Critical patent/NL7609874A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL7609874A 1975-09-08 1976-09-06 Werkwijze ter bereiding van nieuwe aminoglyco- siden. NL7609874A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/611,349 US3996205A (en) 1975-09-08 1975-09-08 Aminoglycoside antibiotics and intermediates

Publications (1)

Publication Number Publication Date
NL7609874A true NL7609874A (nl) 1977-03-10

Family

ID=24448676

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7609874A NL7609874A (nl) 1975-09-08 1976-09-06 Werkwijze ter bereiding van nieuwe aminoglyco- siden.

Country Status (14)

Country Link
US (1) US3996205A (nl)
JP (1) JPS5233649A (nl)
AU (1) AU506262B2 (nl)
BE (1) BE845942A (nl)
CA (1) CA1067899A (nl)
CH (1) CH626896A5 (nl)
DE (1) DE2638794A1 (nl)
FR (2) FR2322608A1 (nl)
GB (1) GB1530643A (nl)
HU (1) HU177271B (nl)
NL (1) NL7609874A (nl)
PL (1) PL111474B1 (nl)
SU (1) SU700066A3 (nl)
ZA (1) ZA764726B (nl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182855A (en) * 1977-05-05 1980-01-08 The Upjohn Company Nitrosugar
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
EP2390255B1 (en) 2006-04-03 2016-07-13 Technion Research & Development Foundation Ltd. Novel aminoglycosides and uses thereof in the treatment of genetic disorders
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
EP3344640A4 (en) 2015-09-02 2019-05-01 Eloxx Pharmaceuticals Ltd. AMINO-LIKES DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF GENETIC DISEASES
CA2996763A1 (en) 2015-09-02 2017-03-09 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
US10786520B2 (en) 2015-09-02 2020-09-29 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
CA3055883A1 (en) 2017-03-15 2018-09-20 Eloxx Pharmaceuticals Ltd. Large scale preparation of pseudo-trisaccharide aminoglycosides and of intermediates thereof
WO2020105054A1 (en) 2018-11-22 2020-05-28 Technion Research & Development Foundation Limited Modified aminoglycoside compounds and uses thereof in disabling bacterial ribosome

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH84A (fr) * 1889-01-10 Fontainemelon Horlogerie Perfectionnement apporté dans la construction des mécanismes de remontoir des montres de tous calibres
JPS507595B1 (nl) * 1970-07-29 1975-03-27
US3792037A (en) * 1971-11-04 1974-02-12 Bristol Myers Co Process for preparing ambutyrosin
CA992535A (en) * 1972-03-08 1976-07-06 Bristol-Myers Squibb Company Antibiotic derivatives
US3897412A (en) * 1972-05-04 1975-07-29 Bristol Myers Co Paromomycin antibiotic derivatives
US3860574A (en) * 1972-12-06 1975-01-14 Bristol Myers Co Derivatives of neomycin b and neomycin c
US3886139A (en) * 1973-02-23 1975-05-27 Bristol Myers Co Derivatives of kanamycin
US3893997A (en) * 1974-07-01 1975-07-08 Smithkline Corp Pseudodisaccharide intermediates

Also Published As

Publication number Publication date
HU177271B (en) 1981-08-28
FR2322608B1 (nl) 1979-09-07
JPS5233649A (en) 1977-03-14
DE2638794A1 (de) 1977-03-10
GB1530643A (en) 1978-11-01
CA1067899A (en) 1979-12-11
SU700066A3 (ru) 1979-11-25
PL192253A1 (pl) 1979-02-26
CH626896A5 (nl) 1981-12-15
AU1662676A (en) 1978-02-09
FR2355852B1 (nl) 1980-04-04
AU506262B2 (en) 1979-12-20
PL111474B1 (en) 1980-08-30
BE845942A (fr) 1977-03-08
US3996205A (en) 1976-12-07
FR2355852A1 (fr) 1978-01-20
ZA764726B (en) 1977-07-27
FR2322608A1 (fr) 1977-04-01

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Legal Events

Date Code Title Description
BV The patent application has lapsed